Intra-cranial hemorrage is a serious condition in infants can result in significant morbidity and mortality in developing countries. 680 infants with intracranial haemorrhage have symptoms for 30-60 days (86.2%). Sex ratio between boys and girls was 3/1. The laboratory findings as followed: prolongation of PT, APTT (94,7%), diminution of factors II,VII,IX in 80% of cases. Clinical manifestations are acute anemia (99.1%), distubance of consiousness (100%);100% have some kind of seizures; 91% in bulging of the anterior fontanel. Subarachnoid hemorrhage was major condition in 90.1% of patients, but allways combined with other lesions. The mortality was 14.7% and survived children had severe psycho-neurological sequelae. Intra-cranial hemorrhagic disease in infants has the characteristics of vitamin K deficiency. The haemorrhagic lesions are diverse and complex. Disease caused high mortality as well as high sequella rates.
Intracranial Hemorrhages , Infant, Epidemiologic Studies, Laboratories, Vietnam