1.The correlation between quality of life (QOL) and medication adherence to antihypertensive medications among middle-aged Filipino adults.
Aiella Antonia B. Recto ; Alexandria H. Requierme ; Katrina Nicole D. Requizo ; Armando Miguel I. Reyes ; Dean Adrian G. Reyes ; John Andrew N. Reyes ; Marcellus Francis L. Ramirez
Journal of Medicine University of Santo Tomas 2026;10(1):1837-1847
INTRODUCTION
Hypertension is a serious public health issue that puts individuals at risk for various morbidity and mortality indicators. One of the most crucial factors in managing blood pressure and preventing complications is medication adherence which is linked to several determinants. This study explored the correlation between medication adherence among middle-aged hypertensive adults and the different domains of quality of life (QOL), which includes physical, psychological, social relationship and environment.
METHODSThis cross-sectional study involved 96 Filipino residents of Brgy. San Jose, Navotas City aged 35 to 65 years old diagnosed with hypertension and prescribed anti-hypertensive medications. Pearson’s correlation coefficient was used to calculate the correlation between different domains of QOL as well as the overall QOL score.
RESULTSResults revealed a statistically significant but weak positive correlation between overall QOL and medication adherence (r = 0.336, p<0.001). Among the QOL domains, environmental domain had the strongest correlation with adherence (r = 0.446, p = 0.00), followed by physical health (r = 0.443, p = 0.01) and psychological well-being (r = 0.382, p = 0.01). The social relationship domain showed negligible correlation (r = 0.163, p = 0.4).
CONCLUSIONThe study demonstrates that while medication adherence is modestly associated with better perceived QOL, especially in physical, psychological and environmental aspects, other factors likely influence both outcomes. These findings highlight the need for holistic, community-based interventions that address not only medication adherence but also environmental and psychosocial barriers to care in managing hypertension.
Human ; Adult: 25-44 Yrs Old ; Middle Aged: 45-64 Yrs Old ; Aged: 65-79 Yrs Old ; Quality Of Life ; Public Health ; Medication Adherence ; Antihypertensive Agents ; Blood Pressure ; Interpersonal Relations
2.Extent of health-promoting lifestyle among student nurses in private schools in Baguio City: A quantitative descriptive research study
Florence L. Pulido ; Gemson Yahweh S. Aquino ; Aira Marie Parungao ; Kyle Cristel B. Baloaloa ; Trinna Camille B. Abrigo ; Clarissa V. Cajayon ; Irish Justine J. Gonzales ; Rhea Kathleen A. Mejia ; Vincent Kyle E. De castro ; Rolando C. Esguerra ; Sofia Rafaela D. Velarde
Acta Medica Philippina 2025;59(Early Access 2025):1-13
INTRODUCTION
The Bachelor of Science in Nursing (BSN) program spans four years and includes general education and professional courses. Student nurses attend lecture hours, clinical duties, and related learning experiences that might be affecting their time in attending to a healthy lifestyle. Health-promoting lifestyle is a multi-dimensional pattern of activities and perceptions that begins with self-motivation and assists in promoting self-improvement and health. The domains of health-promoting lifestyle are essential factors to further improve their way of dealing with daily challenges. Multiple factors can also influence student nurses’ lifestyles, including their separation from family, busy schedules, and dietary choices. A study highlights various factors affecting student nurses' lifestyles, underscoring the need for tailored health promotion strategies and curriculum enhancements. Research into these domains can better equip future healthcare leaders. Gender, year level, and living arrangements influence student nurses' lifestyles, prompting researchers to investigate the extent of health-promoting lifestyles among them and differences based on these factors. By addressing these domains and conducting further research, nursing education and practice can better prepare future healthcare leaders to promote health and lifestyle effectively within their communities.
OBJECTIVESTo determine the extent of health-promoting lifestyle among student nurses and identify the significant differences according to gender, year level, and living arrangement.
METHODSA quantitative, descriptive research design was used with 360 respondents, employing Yamane’s formula and quota sampling. The study adopted the Health-Promoting Lifestyle II questionnaire with a validity of 0.962.
RESULTSStudent nurses often engage in health promoting behaviors (mean=2.56). Male student nurses reported higher scores in health responsibility, physical activity, spiritual growth, and stress management compared to female students (p=0.40). Level IV students engaged in health-promoting activities more frequently than Level I students (p=0.74). Living arrangements did not significantly impact health-promoting lifestyles (p=0.99).
CONCLUSIONNo significant difference in health-promoting lifestyles among student nurses. Respondents demonstrated the least health-promoting lifestyle behaviors in the domains of health responsibility, nutrition, and physical activity. In contrast, spiritual growth, interpersonal relations, and stress management attained the highest mean scores.
Human ; Physical Activity ; Exercise ; Interpersonal Relations ; Students, Nursing ; Life Style
3.Extent of health-promoting lifestyle among student nurses in private schools in Baguio City: A quantitative descriptive research study.
Florence L. PULIDO ; Gemson Yahweh S. AQUINO ; Aira Marie PARUNGAO ; Kyle Cristel B. BALOALOA ; Trinna Camille B. ABRIGO ; Clarissa V. CAJAYON ; Irish Justine J. GONZALES ; Rhea Kathleen A. MEJIA ; Vincent Kyle E. DE CASTRO ; Rolando C. ESGUERRA ; Sofia Rafaela D. VELARDE
Acta Medica Philippina 2025;59(19):30-42
INTRODUCTION
The Bachelor of Science in Nursing (BSN) program spans four years and includes general education and professional courses. Student nurses attend lecture hours, clinical duties, and related learning experiences that might be affecting their time in attending to a healthy lifestyle. Health-promoting lifestyle is a multi-dimensional pattern of activities and perceptions that begins with self-motivation and assists in promoting self-improvement and health. The domains of health-promoting lifestyle are essential factors to further improve their way of dealing with daily challenges. Multiple factors can also influence student nurses’ lifestyles, including their separation from family, busy schedules, and dietary choices. A study highlights various factors affecting student nurses' lifestyles, underscoring the need for tailored health promotion strategies and curriculum enhancements. Research into these domains can better equip future healthcare leaders. Gender, year level, and living arrangements influence student nurses' lifestyles, prompting researchers to investigate the extent of health-promoting lifestyles among them and differences based on these factors. By addressing these domains and conducting further research, nursing education and practice can better prepare future healthcare leaders to promote health and lifestyle effectively within their communities.
OBJECTIVESTo determine the extent of health-promoting lifestyle among student nurses and identify the significant differences according to gender, year level, and living arrangement.
METHODSA quantitative, descriptive research design was used with 360 respondents, employing Yamane’s formula and quota sampling. The study adopted the Health-Promoting Lifestyle II questionnaire with a validity of 0.962.
RESULTSStudent nurses often engage in health promoting behaviors (mean=2.56). Male student nurses reported higher scores in health responsibility, physical activity, spiritual growth, and stress management compared to female students (p=0.40). Level IV students engaged in health-promoting activities more frequently than Level I students (p=0.74). Living arrangements did not significantly impact health-promoting lifestyles (p=0.99).
CONCLUSIONNo significant difference in health-promoting lifestyles among student nurses. Respondents demonstrated the least health-promoting lifestyle behaviors in the domains of health responsibility, nutrition, and physical activity. In contrast, spiritual growth, interpersonal relations, and stress management attained the highest mean scores.
Human ; Physical Activity ; Exercise ; Interpersonal Relations ; Students, Nursing ; Life Style
4.Association between levels of satisfaction with interpersonal relationships and insomnia symptoms among women working in aged-care services in Japan.
Ryuichiro WATANABE ; Ai IKEDA ; Hadrien CHARVAT ; Setsuko SATO ; Yuka SUZUKI ; Koutatsu MARUYAMA ; Kiyohide TOMOOKA ; Hiroo WADA ; Yasunari KOYAMA ; Takeshi TANIGAWA
Environmental Health and Preventive Medicine 2025;30():47-47
BACKGROUND:
The demand for aged-care services in Japan has surged due to the country's aging population. Furthermore, nationwide survey on the current state of aged-care services revealed that the primary reason for the resignation of women working in these sectors was poor interpersonal relationships. Moreover, given that women working in aged-care services work in shifts around the clock to manage the health and safety of the people in their care, they are at high risk of health-related issues including insomnia symptoms. Thus, we aim to examine the association between levels of satisfaction with interpersonal relationships (LSIR) and insomnia symptoms for women working in aged-care services in Japan, as well as the effect of work-life imbalance on the association between LSIR and insomnia symptoms.
METHODS:
In this cross-sectional study, the participants were 472 women aged 18-60 years who worked in aged-care services in Japan in 2014-2016. Insomnia symptoms were measured using the Athens Insomnia Scale, and scores of 6 or greater indicated the presence of insomnia. LSIR were assessed through self-administered questionnaires and evaluated at three levels. The association between LSIR and insomnia symptoms was evaluated using a multinominal logistic regression model. Path analysis was used to examine the potential effects of LSIR on insomnia symptoms by incorporating covariates such as work-family conflict, marital status, and depressive symptoms.
RESULTS:
Compared to high LSIR, the multivariable-adjusted odds ratios (95% confidence interval) of insomnia symptoms were respectively 1.36 (0.81-2.30) and 2.42 (1.11-5.23) for medium and low LSIR. The path analysis showed that low LSIR were significantly associated with having high work-to-family (W-to-F) conflict and being single.
CONCLUSIONS
Low LSIR were significantly associated with insomnia symptoms among women working in aged-care services in Japan. High W-to-F conflict exacerbated this relationship. Therefore, enhancing interpersonal relationships may be necessary for preventing insomnia. However, due to the cross-sectional nature of our study, causality cannot be inferred. Further longitudinal research is needed to better understand these associations.
Humans
;
Japan/epidemiology*
;
Sleep Initiation and Maintenance Disorders/psychology*
;
Female
;
Middle Aged
;
Adult
;
Cross-Sectional Studies
;
Interpersonal Relations
;
Young Adult
;
Adolescent
;
Personal Satisfaction
;
Health Services for the Aged/statistics & numerical data*
5.Preventive role of community-level social capital in the need for long-term care and impairment in instrumental activities of daily living: a multilevel analysis.
Hitomi MATSUURA ; Yoko HATONO ; Isao SAITO
Environmental Health and Preventive Medicine 2023;28():15-15
BACKGROUND:
Individual-level social capital is an important determinant of older adults' long-term care needs; however, there is scant evidence regarding community-level social capital. Therefore, we investigated the association between community-level social capital and the prevalence of the need for long-term care among older adults.
METHODS:
Between January and February 2018, a cross-sectional survey was conducted among all older adults (n = 13,558) aged 65 to 74 years in a rural municipality in Japan (total population, n = 72,833). A self-reported questionnaire was used to identify community-level social capital, comprising civic participation, social cohesion, and reciprocity. A multilevel logistic regression analysis was performed to estimate the odds ratios of the need for long-term care and a decline in social activity competence as assessed by instrumental activities of daily living. For the analysis, the community levels were divided into 76 voting districts and adjusted for daily life, lifestyle, socioeconomic status, health conditions, and the three social capital subscale scores at the individual level.
RESULTS:
After adjusting for the covariates, we observed a tendency that a higher community level of reciprocity was associated with a lower prevalence of long-term care needs (OR: 0.86, 95% confidence interval: 0.75-1.00), whereas a high community level of social cohesion was associated with a significantly reduced decline in instrumental activities of daily living (OR per standard deviation increase: 0.87, 95% confidence interval: 0.79-0.96). No significant association was found with civic participation. Similarly, individual-level social capital was associated with the need for long-term care and decline in instrumental activities of daily living.
CONCLUSIONS
Our findings suggest that good community-level reciprocity or social cohesion as well as good individual social capital status may help prevent the need for long-term care among older adults.
Humans
;
Aged
;
Interpersonal Relations
;
Activities of Daily Living
;
Social Participation
;
Social Capital
;
Multilevel Analysis
;
Cross-Sectional Studies
;
Long-Term Care
;
Japan/epidemiology*
;
Social Support
6.Neuro-Behavioral Dynamic Prediction of Interpersonal Cooperation and Aggression.
Wei WANG ; Chao FU ; Xiangzeng KONG ; Roman OSINSKY ; Johannes HEWIG ; Yiwen WANG
Neuroscience Bulletin 2022;38(3):275-289
How to quickly predict an individual's behavioral choices is an important issue in the field of human behavior research. Using noninvasive electroencephalography, we aimed to identify neural markers in the prior outcome-evaluation stage and the current option-assessment stage of the chicken game that predict an individual's behavioral choices in the subsequent decision-output stage. Hierarchical linear modeling-based brain-behavior association analyses revealed that midfrontal theta oscillation in the prior outcome-evaluation stage positively predicted subsequent aggressive choices; also, beta oscillation in the current option-assessment stage positively predicted subsequent cooperative choices. These findings provide electrophysiological evidence for the three-stage theory of decision-making and strengthen the feasibility of predicting an individual's behavioral choices using neural oscillations.
Aggression/physiology*
;
Brain
;
Electroencephalography
;
Interpersonal Relations
7.Mediating Effects of Interpersonal Problems in the Relationship between Social Network Service Use Tendency and Depression among University Students
Min Jeong PARK ; Mi Young CHUNG
Journal of Korean Academy of Community Health Nursing 2019;30(1):38-46
PURPOSE: The purpose of this study isto identify the mediating effects of interpersonal problems in the relationship between Social Network Service (SNS) use tendency and depression among university students. METHODS: Data were collected from April 28 to May 7, 2018 and the participants included 222 university students, who responded to the question regarding SNS use tendency, interpersonal problems and depression. The data were analyzed by descriptive statistics, t-test, ANOVA, Pearson's correlation coefficients, and multiple regression using the SPSS/WIN 23.0 program. RESULTS: A positive correlation is found between depression and SNS use tendency (r=.24, p<.001), and among interpersonal problems (r=.62, p<.001), SNS use tendency and interpersonal problems (r=.34, p<.001). Interpersonal problems have a full mediating effect on the relationship between SNS use tendency and depression (Sobel test: 5.24, p<.001). CONCLUSION: These results suggest that it is important to manage interpersonal problems to prevent depression caused by SNS use tendency.
Depression
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Humans
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Interpersonal Relations
;
Negotiating
8.Influence of clozapine on neurodevelopmental protein expression and behavioral patterns in animal model of psychiatric disorder induced by low-level of lead
Hwayoung LEE ; Minyoung LEE ; Hyung Ki KIM ; Young Ock KIM ; Jun Tack KWON ; Hak Jae KIM
The Korean Journal of Physiology and Pharmacology 2019;23(6):467-474
Exposure to lead during pregnancy is a risk factor for the development of psychiatric disorders in the offspring. In this study, we investigated whether exposure to low levels of lead acetate (0.2%) in drinking water during pregnancy and lactation causes behavioral impairment and affects the expression of proteins associated with neurodevelopment. Lead exposure altered several parameters in rat offspring compared with those unexposed in open-field, social interaction, and pre-pulse inhibition tests. These parameters were restored to normal levels after clozapine treatment. Western blot and immunohistochemical analyses of the hippocampus revealed that several neurodevelopmental proteins were downregulated in lead-exposed rats. The expression was normalized after clozapine treatment (5 mg/kg/day, postnatal day 35–56). These findings demonstrate that downregulation of several proteins in lead-exposed rats affected subsequent behavioral changes. Our results suggest that lead exposure in early life may induce psychiatric disorders and treatment with antipsychotics such as clozapine may reduce their incidence.
Animals
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Antipsychotic Agents
;
Behavior Rating Scale
;
Blotting, Western
;
Clozapine
;
Down-Regulation
;
Drinking Water
;
Female
;
Hippocampus
;
Incidence
;
Interpersonal Relations
;
Lactation
;
Lead Poisoning
;
Models, Animal
;
Neurodevelopmental Disorders
;
Pregnancy
;
Rats
;
Risk Factors
9.Early-Life Stress in D2 Heterozygous Mice Promotes Autistic-like Behaviors through the Downregulation of the BDNF-TrkB Pathway in the Dorsal Striatum
Experimental Neurobiology 2019;28(3):337-351
A number of specific genetic variants including gene mutations and single nucleotide variations have been identified in genomewide association studies of autism spectrum disorder (ASD). ASD phenotypes in individuals carrying specific genetic variations are manifest mostly in a heterozygous state. Furthermore, individuals with most genetic variants show incomplete penetrance and phenotypic variability, suggesting that non-genetic factors are also involved in developing ASD. However, the mechanisms of how genetic and environmental factors interactively promote ASD are not clearly understood. In the present study, we investigated whether early-life stress (ELS) in D2 dopamine receptor heterozygous knockout (D2(+/−)) mice induces ASD-like symptoms. To address that, we exposed D2 heterozygous pups to maternal separation stress for 3 h daily for 13 days beginning on postnatal day 2. D2(+/−) adult mice that had experienced ELS exhibited impaired sociability in the three-chamber test and home-cage social interaction test and increased grooming behavior, whereas wildtype littermates exposed to ELS did not show those phenotypes. ELS-exposed D2(+/−) mice had decreased levels of BDNF, TrkB, phospho-ERK1/2 and phospho-CREB in the dorsal striatum. Administration of the TrkB agonist 7,8-dihydroxyflavone (7,8-DHF) to ELS-exposed D2(+/−) mice rescued the sociability deficits and repetitive behavior. In contrast, behavioral rescue by 7,8-DHF in ELS-exposed D2(+/−) mice was blocked when TrkB expression in the dorsal striatum was locally inhibited by the injection of TrkB-siRNA. Together, our results suggest that the interaction between ELS and defective D2 gene function promotes autistic-like behaviors by downregulating the BDNF-TrkB pathway in the dorsal striatum.
Adult
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Animals
;
Autism Spectrum Disorder
;
Brain-Derived Neurotrophic Factor
;
Down-Regulation
;
Genetic Variation
;
Grooming
;
Humans
;
Interpersonal Relations
;
Mice
;
Penetrance
;
Phenotype
;
Receptor, trkB
;
Receptors, Dopamine
10.Determining the Relationship among Organizational Commitment, Occupational Stress, and Interpersonal Relations according to Adult Attachment Styles of Clinical Dental Hygienists
Journal of Dental Hygiene Science 2019;19(2):122-132
BACKGROUND: This study aimed to identify the types of adult attachment and determine the relationship between adult attachment and job factors in dental hygienists. Ultimately, it was necessary to identify the need for a secure attachment to improve the quality of clinical dental hygienist's services. METHODS: Data of 454 clinical dental hygienists working in dental hospitals or clinics were collected. The research tools consisted of items related to the general and work characteristics of dental hygienists (9 items), adult attachment styles (36 items), organizational commitments (12 items), occupational stress (15 items), and interpersonal relations (18 items). Cronbach's α of each tool was ≥0.7. RESULTS: Most of the participants had fearful attachment styles, followed by dismissing-avoidance, security, and preoccupation. Security was the highest level of organizational commitment according to the adult attachment style, although the differences of the levels were insignificant. For occupational stress, preoccupation was the highest, followed by fearful, security, and dismissing-avoidance, and the differences were significant (p<0.001). For interpersonal relations, security was the highest, followed by preoccupation, dismissing-avoidance, and fearful in order, and the differences were significant (p<0.001). CONCLUSION: Job stress and interpersonal relation ability according to the adult attachment style of clinical dental hygienists had significant results. Thus, the development of attachment improvement programs by personal style, development of differentiated clinical education and its application, and improvements in the adult attachment styles of clinical dental hygienists would be required rather than simply presenting the needs to collectively improvement the working environment.
Adult
;
Dental Hygienists
;
Education
;
Humans
;
Interpersonal Relations


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