Children with disabilities are at an increased risk of experiencing child maltreatment (CM). We aimed to estimate the prevalence of different forms of CM among children with autism spectrum disorder (ASD) in Bangladesh. We interviewed 45 randomly selected mothers of ASD children who attended a tertiary care hospital in Dhaka, Bangladesh, to treat their children. Data regarding CM was collected using a standard screening tool recommended by the International Society for the Prevention of Child Abuse and Neglect (ISPCAN). We asked mothers to report about their child-rearing practices to identify CM, including physical, psychological, and sexual abuse, and neglect, along with their non-violent disciplinary practices. The children's age range was 3 to 9 years, and approximately 82 percent were boys. All children were found to have experiences of physical and psychological abuse throughout their childhood. Seventy-three percent of children experienced neglect during the past year while 82 percent during their entire childhood. The reported prevalence of sexual abuse was 4.4 percent in the past year and 8.9 percent during their childhood. However, all parents followed non-violent disciplinary practices, and the prevalence of maltreatment did not differ between boys and girls. Higher instances of CM in Bangladesh, especially among ASD children, raise concern for its adverse social consequences and calls for appropriate mitigation practices as proclaimed by the United Nations Child Rights Charter.

AIMTo determine the frequency of genetic deletions within the azoospermia factors in Egyptian infertile males.

METHODSThe Yq microdeletions in 33 infertile males with undetectable chromosomal anomalies were examined by mutiplex polymerase chain reaction (PCR). Deletions were confirmed using single PCR amplifications.

RESULTSFour out of the total 33 (12 %) men had Yq(11) microdeletions, thus supporting the average reported figures in other populations. Three of those 4 cases had single short tandem sequence deletions with discrete histological findings of their testes. Single sY272 deletion within AZFc was associated with Sertoli cell only syndrome, whereas a patient with isolated sY84 deletion within AZFa had immature testicular structure. The remaining case had a large deletion in AZFa-c and short stature.

CONCLUSIONThe present study supports the hypothesis that the Yq(11) encompasses genetic determinants of stature besides genes controlling spermatogenesis.

Adult ; Chromosomes, Human, Y ; genetics ; Egypt ; Follicle Stimulating Hormone ; blood ; Gene Deletion ; Humans ; Infertility, Male ; genetics ; pathology ; Luteinizing Hormone ; blood ; Male ; Polymerase Chain Reaction ; Sertoli Cells ; pathology ; Syndrome ; Testis ; pathology ; Testosterone ; blood