1.Oligohydramnios affects pulmonary functional/structural abnormalities in school-aged children with bronchopulmonary dysplasia
Jeong Eun SHIN ; Soon Min LEE ; Mi-Jung LEE ; Jungho HAN ; Joohee LIM ; Haerin JANG ; Ho Seon EUN ; Min Soo PARK ; Soo Yeon KIM ; Myung Hyun SOHN ; Ji Ye JUNG ; Kyung Won KIM
Clinical and Experimental Pediatrics 2024;67(5):257-266
Background:
The relationship between early life factors and childhood pulmonary function and structure in preterm infants remains unclear.Purpose: This study investigated the impact of bronchopulmonary dysplasia (BPD) and perinatal factors on childhood pulmonary function and structure.
Methods:
This longitudinal cohort study included preterm participants aged ≥5 years born between 2005 and 2015. The children were grouped by BPD severity according to National Institutes of Health criteria. Pulmonary function tests (PFTs) were performed using spirometry. Chest computed tomography (CT) scans were obtained and scored for hyperaeration or parenchymal lesions. PFT results and chest CT scores were analyzed with perinatal factors.
Results:
A total 150 children (66 females) aged 7.7 years (6.4–9.9 years) were categorized into non/mild BPD (n=68), moderate BPD (n=39), and severe BPD (n=43) groups. The median z score for forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), FEV1/FVC ratio, and forced midexpiratory flow (FEF25%–75%) were significantly lower in the severe versus non/mild BPD group (-1.24 vs. -0.18, -0.22 vs. 0.41, -1.80 vs. -1.12, and -1.88 vs. -1.00, respectively; all P<0.05). The median z scores of FEV1, FEV1/ FVC, and FEF25%–75% among asymptomatic patients were also significantly lower in the severe versus non/mild BPD group (-0.82 vs. 0.09, -1.68 vs. -0.87, -1.59 vs. -0.61, respectively; all P<0.05). The severe BPD group had a higher median (range) CT score than the non/mild BPD group (6 [0–12] vs. 1 [0–10], P<0.001). Prenatal oligohydramnios was strongly associated with both low pulmonary function (FEV1/FVC
2.Oligohydramnios affects pulmonary functional/structural abnormalities in school-aged children with bronchopulmonary dysplasia
Jeong Eun SHIN ; Soon Min LEE ; Mi-Jung LEE ; Jungho HAN ; Joohee LIM ; Haerin JANG ; Ho Seon EUN ; Min Soo PARK ; Soo Yeon KIM ; Myung Hyun SOHN ; Ji Ye JUNG ; Kyung Won KIM
Clinical and Experimental Pediatrics 2024;67(5):257-266
Background:
The relationship between early life factors and childhood pulmonary function and structure in preterm infants remains unclear.Purpose: This study investigated the impact of bronchopulmonary dysplasia (BPD) and perinatal factors on childhood pulmonary function and structure.
Methods:
This longitudinal cohort study included preterm participants aged ≥5 years born between 2005 and 2015. The children were grouped by BPD severity according to National Institutes of Health criteria. Pulmonary function tests (PFTs) were performed using spirometry. Chest computed tomography (CT) scans were obtained and scored for hyperaeration or parenchymal lesions. PFT results and chest CT scores were analyzed with perinatal factors.
Results:
A total 150 children (66 females) aged 7.7 years (6.4–9.9 years) were categorized into non/mild BPD (n=68), moderate BPD (n=39), and severe BPD (n=43) groups. The median z score for forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), FEV1/FVC ratio, and forced midexpiratory flow (FEF25%–75%) were significantly lower in the severe versus non/mild BPD group (-1.24 vs. -0.18, -0.22 vs. 0.41, -1.80 vs. -1.12, and -1.88 vs. -1.00, respectively; all P<0.05). The median z scores of FEV1, FEV1/ FVC, and FEF25%–75% among asymptomatic patients were also significantly lower in the severe versus non/mild BPD group (-0.82 vs. 0.09, -1.68 vs. -0.87, -1.59 vs. -0.61, respectively; all P<0.05). The severe BPD group had a higher median (range) CT score than the non/mild BPD group (6 [0–12] vs. 1 [0–10], P<0.001). Prenatal oligohydramnios was strongly associated with both low pulmonary function (FEV1/FVC
3.Oligohydramnios affects pulmonary functional/structural abnormalities in school-aged children with bronchopulmonary dysplasia
Jeong Eun SHIN ; Soon Min LEE ; Mi-Jung LEE ; Jungho HAN ; Joohee LIM ; Haerin JANG ; Ho Seon EUN ; Min Soo PARK ; Soo Yeon KIM ; Myung Hyun SOHN ; Ji Ye JUNG ; Kyung Won KIM
Clinical and Experimental Pediatrics 2024;67(5):257-266
Background:
The relationship between early life factors and childhood pulmonary function and structure in preterm infants remains unclear.Purpose: This study investigated the impact of bronchopulmonary dysplasia (BPD) and perinatal factors on childhood pulmonary function and structure.
Methods:
This longitudinal cohort study included preterm participants aged ≥5 years born between 2005 and 2015. The children were grouped by BPD severity according to National Institutes of Health criteria. Pulmonary function tests (PFTs) were performed using spirometry. Chest computed tomography (CT) scans were obtained and scored for hyperaeration or parenchymal lesions. PFT results and chest CT scores were analyzed with perinatal factors.
Results:
A total 150 children (66 females) aged 7.7 years (6.4–9.9 years) were categorized into non/mild BPD (n=68), moderate BPD (n=39), and severe BPD (n=43) groups. The median z score for forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), FEV1/FVC ratio, and forced midexpiratory flow (FEF25%–75%) were significantly lower in the severe versus non/mild BPD group (-1.24 vs. -0.18, -0.22 vs. 0.41, -1.80 vs. -1.12, and -1.88 vs. -1.00, respectively; all P<0.05). The median z scores of FEV1, FEV1/ FVC, and FEF25%–75% among asymptomatic patients were also significantly lower in the severe versus non/mild BPD group (-0.82 vs. 0.09, -1.68 vs. -0.87, -1.59 vs. -0.61, respectively; all P<0.05). The severe BPD group had a higher median (range) CT score than the non/mild BPD group (6 [0–12] vs. 1 [0–10], P<0.001). Prenatal oligohydramnios was strongly associated with both low pulmonary function (FEV1/FVC
4.Oligohydramnios affects pulmonary functional/structural abnormalities in school-aged children with bronchopulmonary dysplasia
Jeong Eun SHIN ; Soon Min LEE ; Mi-Jung LEE ; Jungho HAN ; Joohee LIM ; Haerin JANG ; Ho Seon EUN ; Min Soo PARK ; Soo Yeon KIM ; Myung Hyun SOHN ; Ji Ye JUNG ; Kyung Won KIM
Clinical and Experimental Pediatrics 2024;67(5):257-266
Background:
The relationship between early life factors and childhood pulmonary function and structure in preterm infants remains unclear.Purpose: This study investigated the impact of bronchopulmonary dysplasia (BPD) and perinatal factors on childhood pulmonary function and structure.
Methods:
This longitudinal cohort study included preterm participants aged ≥5 years born between 2005 and 2015. The children were grouped by BPD severity according to National Institutes of Health criteria. Pulmonary function tests (PFTs) were performed using spirometry. Chest computed tomography (CT) scans were obtained and scored for hyperaeration or parenchymal lesions. PFT results and chest CT scores were analyzed with perinatal factors.
Results:
A total 150 children (66 females) aged 7.7 years (6.4–9.9 years) were categorized into non/mild BPD (n=68), moderate BPD (n=39), and severe BPD (n=43) groups. The median z score for forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), FEV1/FVC ratio, and forced midexpiratory flow (FEF25%–75%) were significantly lower in the severe versus non/mild BPD group (-1.24 vs. -0.18, -0.22 vs. 0.41, -1.80 vs. -1.12, and -1.88 vs. -1.00, respectively; all P<0.05). The median z scores of FEV1, FEV1/ FVC, and FEF25%–75% among asymptomatic patients were also significantly lower in the severe versus non/mild BPD group (-0.82 vs. 0.09, -1.68 vs. -0.87, -1.59 vs. -0.61, respectively; all P<0.05). The severe BPD group had a higher median (range) CT score than the non/mild BPD group (6 [0–12] vs. 1 [0–10], P<0.001). Prenatal oligohydramnios was strongly associated with both low pulmonary function (FEV1/FVC
5.Establishing Integrated Treatment Centers to Improve Mental Health Services: International Examples and Strategies for South Korea
Han-Sung LEE ; Hyunju LEE ; Yu Jin LEE ; Soon-Beom HONG ; Se Hyun KIM ; Hye Yoon PARK ; Soo-Hee CHOI ; Jee Eun PARK ; Sang Jin RHEE ; Juwon LEE ; Sukkyung LEE ; Jee Hoon SOHN ; Yong Min AHN
Journal of Korean Neuropsychiatric Association 2024;63(4):207-217
The global burden of mental illness has increased significantly since the COVID-19 pandemic. In South Korea, despite this rising burden, the utilization of mental health services remains critically low compared to other countries. This study evaluated successful integrated treatment centers from various countries, including the United States, the United Kingdom, and Australia, to identify the best practices that can be applied to South Korean society. These international examples informed the development of Mind the SHIM (SNUH Health in Mind) center, an integrated treatment model designed to address the gaps in non-pharmacological mental health services in South Korea. Mind the SHIM center focuses on developing and validating programs tailored to local needs, emphasizing professional education, systematic program delivery, and community collaboration. The biopsychosocial approach of the center is expected to enhance the overall quality of life of the patients and increase the utilization of mental health services, reducing the broader economic and social burden of mental illness in South Korea.
6.Establishing Integrated Treatment Centers to Improve Mental Health Services: International Examples and Strategies for South Korea
Han-Sung LEE ; Hyunju LEE ; Yu Jin LEE ; Soon-Beom HONG ; Se Hyun KIM ; Hye Yoon PARK ; Soo-Hee CHOI ; Jee Eun PARK ; Sang Jin RHEE ; Juwon LEE ; Sukkyung LEE ; Jee Hoon SOHN ; Yong Min AHN
Journal of Korean Neuropsychiatric Association 2024;63(4):207-217
The global burden of mental illness has increased significantly since the COVID-19 pandemic. In South Korea, despite this rising burden, the utilization of mental health services remains critically low compared to other countries. This study evaluated successful integrated treatment centers from various countries, including the United States, the United Kingdom, and Australia, to identify the best practices that can be applied to South Korean society. These international examples informed the development of Mind the SHIM (SNUH Health in Mind) center, an integrated treatment model designed to address the gaps in non-pharmacological mental health services in South Korea. Mind the SHIM center focuses on developing and validating programs tailored to local needs, emphasizing professional education, systematic program delivery, and community collaboration. The biopsychosocial approach of the center is expected to enhance the overall quality of life of the patients and increase the utilization of mental health services, reducing the broader economic and social burden of mental illness in South Korea.
7.Enhancing Communication on Medication Side Effects: Insights from a Survey Study
Ji Hye CHOI ; Hye Seong HAN ; Mi Kyong SHIM ; Hyun Soon SOHN
Korean Journal of Clinical Pharmacy 2024;34(2):126-133
Background:
Medication’s benefits and harms require careful management. Laws mandate pharmacists to provide essential med-ication details since inadequate counseling may pose risks. This study explores public expectations for pharmacist-provided side effect information to enhance safety.
Methods:
A self-developed questionnaire was created for participant to self-report, refined through pilot surveys with experts and laypersons. Nineteen items were categorized into four sections, using closed-ended ques-tions. Adults over 20, having obtained prescription medications within the past year, were surveyed via convenience sampling.Data analysis employed descriptive statistics and T-tests using IBM SPSS Statistics 21 and Microsoft Excel.
Results:
The study involved 189 participants, with a slightly higher proportion of females (59.3%) than males (40.7%), predominantly in their 20s (45.0%) and college graduates (57.1%). Health professionals represented 76.2% of respondents. Over half visited pharmacies at least 5 times yearly for prescriptions. Indirect experience with side effects was more common (30.2%) than direct experience (17.5%). Most (82.0%) showed interest in media-reported side effect events. Satisfaction with pharmacist-provided side effect explanations was low (59.7%), but importance was high (98.9%). Preferences favored combined verbal and written explanations (65.1%), with a majority desiring explanations for common but less serious side effects (82.5%). Healthcare professionals found explanations significantly more sufficient than non-professionals did. Older individuals, those living with elderly, and frequent pharmacy visitors attributed greater importance to pharmacist-provided explanations.
Conclusion
Koreans view pharmacist-pro-vided medication side effect explanations as vital but find current services lacking. Enhancements in content and delivery meth-ods are needed in pharmacy counseling to meet public expectations.
8.A Survey of Public Preferences on Repeat Dispensing
Young Mi LEE ; Daejin KIM ; Eunjoo LEE ; Hyun Soon SOHN
Korean Journal of Clinical Pharmacy 2024;34(1):30-38
Background:
This study examined the public’s perceptions of repeat dispensing as one of the measures to reduce the harmful effects of long-term prescriptions in Korea.
Methods:
From January 11 to 25, 2021, an online survey was conducted for adults using convenience sampling. A self-developed questionnaire was used.
Results:
There were 310 respondents, of which 228(73.5%) preferred repeat dispensing. When considering the additional fee payment, 188 (60.6%) preferred repeat dispensing, and54 (67.5%) out of a total of 80 chronic disease patients preferred it. It was confirmed that there was a difference in the willingnessto repeat dispensing considering the additional cost depending on whether the patient had a chronic disease and the distance from home to the nearest pharmacy. As a result of subgroup analysis for patients with chronic diseases, frequency of outpatient visit, number of prescription days, method of packaging pharmaceuticals, and distance from home to the nearest pharmacy were iden-tified as variables that could well predict the willingness to repeat dispensing considering paying additional fees. The preferencefor repeat dispensing may vary depending on conditions such as additional cost range, frequency and period of prescription use, disease and patient characteristics, so a careful approach is necessary.
Conclusion
It is necessary for the government to consider the introduction of repeat dispensing with interest in the public demand.
9.Enhancing Communication on Medication Side Effects: Insights from a Survey Study
Ji Hye CHOI ; Hye Seong HAN ; Mi Kyong SHIM ; Hyun Soon SOHN
Korean Journal of Clinical Pharmacy 2024;34(2):126-133
Background:
Medication’s benefits and harms require careful management. Laws mandate pharmacists to provide essential med-ication details since inadequate counseling may pose risks. This study explores public expectations for pharmacist-provided side effect information to enhance safety.
Methods:
A self-developed questionnaire was created for participant to self-report, refined through pilot surveys with experts and laypersons. Nineteen items were categorized into four sections, using closed-ended ques-tions. Adults over 20, having obtained prescription medications within the past year, were surveyed via convenience sampling.Data analysis employed descriptive statistics and T-tests using IBM SPSS Statistics 21 and Microsoft Excel.
Results:
The study involved 189 participants, with a slightly higher proportion of females (59.3%) than males (40.7%), predominantly in their 20s (45.0%) and college graduates (57.1%). Health professionals represented 76.2% of respondents. Over half visited pharmacies at least 5 times yearly for prescriptions. Indirect experience with side effects was more common (30.2%) than direct experience (17.5%). Most (82.0%) showed interest in media-reported side effect events. Satisfaction with pharmacist-provided side effect explanations was low (59.7%), but importance was high (98.9%). Preferences favored combined verbal and written explanations (65.1%), with a majority desiring explanations for common but less serious side effects (82.5%). Healthcare professionals found explanations significantly more sufficient than non-professionals did. Older individuals, those living with elderly, and frequent pharmacy visitors attributed greater importance to pharmacist-provided explanations.
Conclusion
Koreans view pharmacist-pro-vided medication side effect explanations as vital but find current services lacking. Enhancements in content and delivery meth-ods are needed in pharmacy counseling to meet public expectations.
10.A Survey of Public Preferences on Repeat Dispensing
Young Mi LEE ; Daejin KIM ; Eunjoo LEE ; Hyun Soon SOHN
Korean Journal of Clinical Pharmacy 2024;34(1):30-38
Background:
This study examined the public’s perceptions of repeat dispensing as one of the measures to reduce the harmful effects of long-term prescriptions in Korea.
Methods:
From January 11 to 25, 2021, an online survey was conducted for adults using convenience sampling. A self-developed questionnaire was used.
Results:
There were 310 respondents, of which 228(73.5%) preferred repeat dispensing. When considering the additional fee payment, 188 (60.6%) preferred repeat dispensing, and54 (67.5%) out of a total of 80 chronic disease patients preferred it. It was confirmed that there was a difference in the willingnessto repeat dispensing considering the additional cost depending on whether the patient had a chronic disease and the distance from home to the nearest pharmacy. As a result of subgroup analysis for patients with chronic diseases, frequency of outpatient visit, number of prescription days, method of packaging pharmaceuticals, and distance from home to the nearest pharmacy were iden-tified as variables that could well predict the willingness to repeat dispensing considering paying additional fees. The preferencefor repeat dispensing may vary depending on conditions such as additional cost range, frequency and period of prescription use, disease and patient characteristics, so a careful approach is necessary.
Conclusion
It is necessary for the government to consider the introduction of repeat dispensing with interest in the public demand.

Result Analysis
Print
Save
E-mail