1.Parental Consent Approaches for Newborn WholeGenome Sequencing–Based Screening
HyeonJeong PARK ; Junghyun LEE ; Wonhoo YOO ; Hannah KIM
Korean Journal of Medical Ethics 2026;29(1):15-29
This study aims to develop a standardized informed consent system for whole-genome sequencing (WGS)-based newborn screening (NBS) in Korea through a policy design approach grounded in the domestic legal and policy context. We conducted an integrated literature review of international norms, domestic legal frameworks, guidelines, and major overseas WGS-based NBS programs using a common analytical framework. To develop a consent model feasible in the Korean context, we also analyzed stakeholder evidence from parent interviews and a clinician survey focused on consentrelated issues. The findings indicate that the current Korean legal and institutional framework does not adequately address long-term storage, reanalysis, recontact, and the transfer of decision-making authority as the child matures. Based on these findings, we propose a Korean informed consent model consisting of a staged consent pathway spanning antenatal, postnatal, and adulthood-related decision points; tiered consent options for the return of results; and safeguards against disadvantage or discrimination related to participation, non-participation, or withdrawal. The study further suggests that implementation will require broader legal and procedural clarification across the relevant regulatory framework, along with the continued development of education and counseling strategies.
2.Status and appropriateness of fasting in the emergency department
Kangbum LEE ; Stephen Gyung Won LEE ; Chang Seob JANG ; Sa Ran LEE ; Hyeonjeong KIM ; Jeong Hwa HONG ; Sumin LEE ; Yeon Kyung KIM
Journal of the Korean Society of Emergency Medicine 2026;37(2):82-88
Objective:
Prolonged fasting has been reported to have a negative effect on patient outcomes. Although fasting is routinely practiced in the emergency department (ED), there is limited evidence on the current status and appropriateness of fasting in the ED. This study examined the status and appropriateness of fasting in the ED and identified the characteristics of patients who experienced unnecessary fasting.
Methods:
A retrospective observational study was performed at an urban ED in Seoul, Korea. The fasting status and characteristics of adult patients who visited the ED and were admitted or discharged between April 1 and April 30, 2022, were analyzed. A checklist for discontinuing fasting in the ED was used to screen for unnecessary fasting.
Results:
Among 2,292 patients who met the study inclusion criteria, all patients were instructed to begin fasting upon ED arrival. Fasting was discontinued by the physician’s order in 300 patients (13.1%). Patients remained fasting for 92.0%±23.2% of their total ED length of stay. Of the 1,577 patients eligible for fasting discontinuation according to the checklist, 249 patients (15.8%) were ordered to discontinue fasting, and 1,328 patients (84.2%) experienced unnecessary fasting.
Conclusion
ED patients spent significant time fasting during their ED length of stay. A high prevalence of unnecessary fasting was identified in the ED.
3.Validity of a self-reported questionnaire on periodontal disease for national epidemiological surveillance among Korean adults
Hyeonjeong GO ; Ji-Hye KIM ; Youn-Hee CHOI
Journal of Korean Academy of Oral Health 2025;49(1):31-39
Objectives:
Clinical examination is considered the gold standard for monitoring periodontal disease. However, it requires significant resources. Self-reported assessment serves as a useful method for screening periodontal diseases in different cohorts. We aimed to evaluate the validity of a selfreported questionnaire for the surveillance of periodontal disease among Korean adults.
Methods:
The participants were 120 patients aged ≥19 years old who were examined using the community periodontal index. The questionnaire comprised 10 questions, translated from an English-version, that was used to identify periodontitis. The predictiveness of the measures from the self-reported questions was assessed by multivariable logistic regression modeling using the area under the receiver operating characteristic curve (AUROC), sensitivity, and specificity.
Results:
For item 3, “Have you ever had treatment for gum disease, such as scaling and root planning”, the adjusted odds ratio was 4.65; 95% confidence interval, 1.22-17.67; and AUROC, 0.82. The sensitivity and specificity of this item were, 0.93 and 0.42, respectively. In Kendall’s Tau-b correlation analysis, items 1 (“Have gum disease”) and 10 Periodontal treatment and surgery under anesthesia”) had the strongest correlations with item 3, with correlation coefficients of 0.48 and 0.42, respectively. A model combining items 1, 3, and 10, adjusted for demographic variables, resulted in an AUROC of 0.86, sensitivity of 0.86, and specificity of 0.26.
Conclusions
An adapted Korean version (“Have gum disease”, “Treatment for gum disease, such as scaling and root planning”, and “periodontal treatment under anesthesia”) of the self-reported questionnaire demonstrated its capacity for epidemiological surveillance of periodontal disease in this study cohort.
4.Validity of a self-reported questionnaire on periodontal disease for national epidemiological surveillance among Korean adults
Hyeonjeong GO ; Ji-Hye KIM ; Youn-Hee CHOI
Journal of Korean Academy of Oral Health 2025;49(1):31-39
Objectives:
Clinical examination is considered the gold standard for monitoring periodontal disease. However, it requires significant resources. Self-reported assessment serves as a useful method for screening periodontal diseases in different cohorts. We aimed to evaluate the validity of a selfreported questionnaire for the surveillance of periodontal disease among Korean adults.
Methods:
The participants were 120 patients aged ≥19 years old who were examined using the community periodontal index. The questionnaire comprised 10 questions, translated from an English-version, that was used to identify periodontitis. The predictiveness of the measures from the self-reported questions was assessed by multivariable logistic regression modeling using the area under the receiver operating characteristic curve (AUROC), sensitivity, and specificity.
Results:
For item 3, “Have you ever had treatment for gum disease, such as scaling and root planning”, the adjusted odds ratio was 4.65; 95% confidence interval, 1.22-17.67; and AUROC, 0.82. The sensitivity and specificity of this item were, 0.93 and 0.42, respectively. In Kendall’s Tau-b correlation analysis, items 1 (“Have gum disease”) and 10 Periodontal treatment and surgery under anesthesia”) had the strongest correlations with item 3, with correlation coefficients of 0.48 and 0.42, respectively. A model combining items 1, 3, and 10, adjusted for demographic variables, resulted in an AUROC of 0.86, sensitivity of 0.86, and specificity of 0.26.
Conclusions
An adapted Korean version (“Have gum disease”, “Treatment for gum disease, such as scaling and root planning”, and “periodontal treatment under anesthesia”) of the self-reported questionnaire demonstrated its capacity for epidemiological surveillance of periodontal disease in this study cohort.
5.Validity of a self-reported questionnaire on periodontal disease for national epidemiological surveillance among Korean adults
Hyeonjeong GO ; Ji-Hye KIM ; Youn-Hee CHOI
Journal of Korean Academy of Oral Health 2025;49(1):31-39
Objectives:
Clinical examination is considered the gold standard for monitoring periodontal disease. However, it requires significant resources. Self-reported assessment serves as a useful method for screening periodontal diseases in different cohorts. We aimed to evaluate the validity of a selfreported questionnaire for the surveillance of periodontal disease among Korean adults.
Methods:
The participants were 120 patients aged ≥19 years old who were examined using the community periodontal index. The questionnaire comprised 10 questions, translated from an English-version, that was used to identify periodontitis. The predictiveness of the measures from the self-reported questions was assessed by multivariable logistic regression modeling using the area under the receiver operating characteristic curve (AUROC), sensitivity, and specificity.
Results:
For item 3, “Have you ever had treatment for gum disease, such as scaling and root planning”, the adjusted odds ratio was 4.65; 95% confidence interval, 1.22-17.67; and AUROC, 0.82. The sensitivity and specificity of this item were, 0.93 and 0.42, respectively. In Kendall’s Tau-b correlation analysis, items 1 (“Have gum disease”) and 10 Periodontal treatment and surgery under anesthesia”) had the strongest correlations with item 3, with correlation coefficients of 0.48 and 0.42, respectively. A model combining items 1, 3, and 10, adjusted for demographic variables, resulted in an AUROC of 0.86, sensitivity of 0.86, and specificity of 0.26.
Conclusions
An adapted Korean version (“Have gum disease”, “Treatment for gum disease, such as scaling and root planning”, and “periodontal treatment under anesthesia”) of the self-reported questionnaire demonstrated its capacity for epidemiological surveillance of periodontal disease in this study cohort.
6.Validity of a self-reported questionnaire on periodontal disease for national epidemiological surveillance among Korean adults
Hyeonjeong GO ; Ji-Hye KIM ; Youn-Hee CHOI
Journal of Korean Academy of Oral Health 2025;49(1):31-39
Objectives:
Clinical examination is considered the gold standard for monitoring periodontal disease. However, it requires significant resources. Self-reported assessment serves as a useful method for screening periodontal diseases in different cohorts. We aimed to evaluate the validity of a selfreported questionnaire for the surveillance of periodontal disease among Korean adults.
Methods:
The participants were 120 patients aged ≥19 years old who were examined using the community periodontal index. The questionnaire comprised 10 questions, translated from an English-version, that was used to identify periodontitis. The predictiveness of the measures from the self-reported questions was assessed by multivariable logistic regression modeling using the area under the receiver operating characteristic curve (AUROC), sensitivity, and specificity.
Results:
For item 3, “Have you ever had treatment for gum disease, such as scaling and root planning”, the adjusted odds ratio was 4.65; 95% confidence interval, 1.22-17.67; and AUROC, 0.82. The sensitivity and specificity of this item were, 0.93 and 0.42, respectively. In Kendall’s Tau-b correlation analysis, items 1 (“Have gum disease”) and 10 Periodontal treatment and surgery under anesthesia”) had the strongest correlations with item 3, with correlation coefficients of 0.48 and 0.42, respectively. A model combining items 1, 3, and 10, adjusted for demographic variables, resulted in an AUROC of 0.86, sensitivity of 0.86, and specificity of 0.26.
Conclusions
An adapted Korean version (“Have gum disease”, “Treatment for gum disease, such as scaling and root planning”, and “periodontal treatment under anesthesia”) of the self-reported questionnaire demonstrated its capacity for epidemiological surveillance of periodontal disease in this study cohort.
7.A Systematic Review for the Development of a Consent System for Newborn Screening Based on Whole-Genome Sequencing (WGS)
HyeonJeong PARK ; Hyunjae CHA ; Wonhoo YOO ; Hannah KIM ; Junhewk KIM ; So-Yoon KIM
Korean Journal of Medical Ethics 2025;28(3):207-228
Informed consent for whole-genome sequencing (WGS)-based newborn screening presents distinctive ethical and legal challenges, particularly in balancing parental consent given on behalf of the child with the progressive realization of children’s rights. This study examines the issues discussed in the literature and proposes consent frameworks that are responsive to evolving clinical and societal contexts. A systematic literature review was conducted in accordance with PRISMA 2020 guidelines, analyzing 19 empirical, normative, and legal studies. The synthesis identified persistent tensions between safeguarding parental autonomy and ensuring the child’s future selfdetermination, alongside challenges in determining the scope, timing, and format of genomic information disclosure. International models increasingly adopt dynamic consent processes, such as staged consent or re-consent upon reaching legal capacity. These approaches illustrate the feasibility of aligning clinical utility, public health objectives, and rights-based ethics within largescale genomic programs. Based on its findings, this study recommends the implementation of staged consent mechanisms, transparent disclosure protocols, and procedural safeguards tailored to domestic legal and political frameworks. Such evolving consent practices are expected to support the development of ethically robust and socially sustainable governance for WGS-based newborn screening.
8.Analysis of the relationship between foodservice staffing and foodservice quality in elderly care facilities in Korea: a cross-sectional study
Hyeonjeong KIM ; Jinhee KWON ; Jungsuk LEE
Korean Journal of Community Nutrition 2025;30(4):296-308
Objectives:
This study was performed to investigate the relationship between foodservice staffing and foodservice quality in elderly care facilities.
Methods:
Data was obtained from the Korean Long-term Care Institute Database and used to analyze 2,084 elderly care facilities operating on-site foodservice. The presence of dietitians and staffing levels for cooking personnel were analyzed by categorizing size according to staffing criteria. Foodservice quality was assessed using food sanitation management and meal service provision as indicators. Descriptive statistical analysis, chi-square test, Fisher’s exact test, and Cochran-Mantel-Haenszel test were conducted to analyze relationships between staffing level and foodservice quality.
Results:
Presence of a dietitian correlated with food sanitation management and meal service provision in groups with 30 or more recipients (P = 0.027, P = 0.049). Elderly care facilities with dietitians had better foodservice quality. After adjusting for size, the presence of dietitians was also found to correlate with food sanitation management (P = 0.024). Staffing levels for cooking personnel were found to correlate with meal service provision only in groups with 38 to 62 recipients. Institutions with larger staffs provided better meal service quality compared to those with basic staffing.
Conclusion
Inclusion of a dietitian and cooking staff size each contribute to enhanced foodservice quality in elderly care facilities, with dietitian inclusion showing a particularly significant association with food sanitation management. These findings suggest the need to revise current staffing and related regulatory standards to optimize deployment of foodservice personnel in elderly care settings. Future studies should focus on developing effective policies for securing qualified foodservice staff and establishing robust quality management systems to enhance overall foodservice quality in long-term care facilities.
9.Effect of prophylactic abdominal drainage on postoperative pain in laparoscopic hemicolectomy for colon cancer: a single-center observational study in Korea
Sung Seo HWANG ; Heung-Kwon OH ; Hye-Rim SHIN ; Tae-Gyun LEE ; Mi Jeong CHOI ; Min Hyeong JO ; Hong-min AHN ; Hyeonjeong PARK ; Hyun Hee SIM ; Eunjeong JI ; Anuj Naresh SINGHI ; Duck-Woo KIM ; Sung-Bum KANG
Journal of Minimally Invasive Surgery 2024;27(2):76-84
Purpose:
This study aimed to evaluate the effect of prophylactic abdominal drainage (AD) in laparoscopic hemicolectomy, focusing on assessing postoperative pain outcomes.
Methods:
Patients were categorized into two groups: those with and without AD (AD group vs.no-AD group). A numerical rating scale (NRS) was used to assess postoperative pain on each postoperative day (POD). Further, the inverse probability of treatment weighting (IPTW) method was used to reduce intergroup bias.
Results:
In total, 204 patients who underwent laparoscopic hemicolectomies by a single surgeon between June 2013 and September 2022 at a single institution were retrospectively reviewed. After adjusting for IPTW, NRS scores on POD 2 were significantly lower in the no-AD group (3.2 ± 0.8 vs. 3.4 ± 0.8, p = 0.043). Further examination of postoperative outcomes showed no statistically significant differences in complications between the AD (17.3%) and no-AD (12.4%) groups (p = 0.170). The postoperative length of hospital stay was 7.3 ± 2.8 days in the AD group and 6.9 ± 3.0 days in the no-AD group, with no significant difference (p = 0.298). Time to first flatus was 3.0 ± 0.9 days in the AD group and 2.7 ± 0.9 days in the no-AD group, with no significant difference (p = 0.078). Regarding readmission within 1 month, there were four cases each in the AD (2.3%) and no-AD (1.7%) groups, with no significant difference (p = 0.733).
Conclusion
Laparoscopic hemicolectomy without AD resulted in no significant differences in postoperative clinical outcomes, except for postoperative pain. This finding suggests that prophylactic AD may exacerbate postoperative pain.
10.Mathematical Modeling of COVID-19 Transmission and Intervention in South Korea: A Review of Literature
Hyojung LEE ; Sol KIM ; Minyoung JEONG ; Eunseo CHOI ; Hyeonjeong AHN ; Jeehyun LEE
Yonsei Medical Journal 2023;64(1):1-10
South Korea implemented interventions to curb the spread of the novel coronavirus disease 2019 (COVID-19) pandemic with discovery of the first case in early 2020. Mathematical modeling designed to reflect the dynamics of disease transmission has been shown to be an important tool for responding to COVID-19. This study aimed to review publications on the structure, method, and role of mathematical models focusing on COVID-19 transmission dynamics in Korea. In total, 42 papers published between August 7, 2020 and August 21, 2022 were studied and reviewed. This study highlights the construction and utilization of mathematical models to help craft strategies for predicting the course of an epidemic and evaluating the effectiveness of control strategies. Despite the limitations caused by a lack of available epidemiological and surveillance data, modeling studies could contribute to providing scientific evidence for policymaking by simulating various scenarios.

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