1.Meta-analysis of Chaihu Shugan powder combined with western medicine in the treatment of post-stroke depression
Xian LIU ; Rou SHEN ; Hujun GUO
China Modern Doctor 2025;63(31):36-42
Objective To systematically evaluate the efficacy of Chaihu Shugan powder combined with western medicine in the treatment of post-stroke depression(PSD),so as to provide a reference for clinical practice.Methods Randomized controlled trials on Chaihu Shugan powder combined with western medicine in the treatment of PSD were retrieved from CNKI,VIP,Wanfang Data Knowledge Service Platform,SinoMed and PubMed.The quality of the included literatures was evaluated using the Cochrane handbook,and data analysis was performed with RevMan 5.3 software.Results A total of 26 literatures involving 2287 patients were included.Meta-analysis showed that there were significant statistical differences between combined group and control group in terms of total effective rates(RR=1.22,95%CI:1.17-1.26,Z=9.82,P<0.000 01),Hamilton depression scale score(SMD=-1.66,95%CI:-2.94--2.22,Z=9.17,P<0.000 01),National Institutes of Health stroke scale score(MD=-1.59,95%CI:-2.14--1.04,Z=5.64,P<0.000 01),5-hydroxytryptamine level(MD=14.95,95%CI:10.07-19.83,Z=6.01,P<0.000 01)and adverse reactions(RR=0.49,95%CI:0.36-0.66,Z=4.64,P<0.000 01).Conclusion Compared with the treatment with western medicine alone,the combination of Chaihu Shugan powder and western medicine in the treatment of PSD has good efficacy and safety.However,given the low quality of the included literature,higher-quality randomized controlled trials are needed for verification in the future.
2.Meta-analysis of Chaihu Shugan powder combined with western medicine in the treatment of post-stroke depression
Xian LIU ; Rou SHEN ; Hujun GUO
China Modern Doctor 2025;63(31):36-42
Objective To systematically evaluate the efficacy of Chaihu Shugan powder combined with western medicine in the treatment of post-stroke depression(PSD),so as to provide a reference for clinical practice.Methods Randomized controlled trials on Chaihu Shugan powder combined with western medicine in the treatment of PSD were retrieved from CNKI,VIP,Wanfang Data Knowledge Service Platform,SinoMed and PubMed.The quality of the included literatures was evaluated using the Cochrane handbook,and data analysis was performed with RevMan 5.3 software.Results A total of 26 literatures involving 2287 patients were included.Meta-analysis showed that there were significant statistical differences between combined group and control group in terms of total effective rates(RR=1.22,95%CI:1.17-1.26,Z=9.82,P<0.000 01),Hamilton depression scale score(SMD=-1.66,95%CI:-2.94--2.22,Z=9.17,P<0.000 01),National Institutes of Health stroke scale score(MD=-1.59,95%CI:-2.14--1.04,Z=5.64,P<0.000 01),5-hydroxytryptamine level(MD=14.95,95%CI:10.07-19.83,Z=6.01,P<0.000 01)and adverse reactions(RR=0.49,95%CI:0.36-0.66,Z=4.64,P<0.000 01).Conclusion Compared with the treatment with western medicine alone,the combination of Chaihu Shugan powder and western medicine in the treatment of PSD has good efficacy and safety.However,given the low quality of the included literature,higher-quality randomized controlled trials are needed for verification in the future.
3.Analysis of 10-year-death cases in hospitalized children in Yuying Children's Hospital of Wenzhou Medical College
Liu LIU ; Lei CHONG ; Li LIN ; Hujun WU ; Shuzhen GUO ; Changchong LI
Chinese Journal of Applied Clinical Pediatrics 2015;30(6):449-452
Objective To analyze the death cases of hospitalized children in Yuying Children's Hospital of Wenzhou Medical College from January 2004 to December 2013,and to detect the age distribution of deaths,the total cost and cost of different diseases,length of hospital stays,season distribution of deaths and mortality rates trends.Methods Five hundred and thirty-one death cases of 0-18 years old hospitalized children from 219 429 cases in Yuying Children's Hospital of Wenzhou Medical College during January 2004 to December 2013 were collected and analyzed.Results From January 2004 to December 2013,the total mortality rate of hospitalized children was 0.24% (531/219 429 cases).The mortality rate of 0-28 d was highest (0.77%).The average economic cost of dead cases was 3.4 times compared with other hospitalized cases,three diseases with highest treatment expenses were congenital malformation,deformations and chromosomal abnormalities ; as well as the respiratory system diseases and tumor.Median hospital stay of the dead cases was 5.8 days.The top five causes of death were certain conditions originating in the perinatal period,such as congenital malformation,deformations and chromosomal abnormalities ; injury,poisoning and certain other consequences of external causes;certain infectious and parasitic diseases;diseases of the respiratory system.From January 2004 to December 2013,the mortality rate declined from 0.34% to 0.12% (x2 =67.138,P < 0.001),and it was in a descending order.Conclusions Related departments of government should pay more attention to perinatal care,promote the congenital diseases screening,prevent respiratory infections,improve the level of emergency room,reduce poisoning and traffic accidents.And different measures should be taken according to the different characteristics of the death causes of different age groups.
4.Disseminated Staphylococcus aureus infection in children:a clinical analysis of 14 cases
Hujun WU ; Shunhang WEN ; Li LIN ; Liu LIU ; Shuzhen GUO ; Changchong LI
Journal of Clinical Pediatrics 2014;(10):936-939
Objective To study the disseminated Staphylococcus aureus infection (DSAI) in children. Method Clinical features, treatment and prognosis data of 14 children with DSAI admitted to Yuying Children’s Hospital Afifliated to Wenzhou Medical University from January 2006 to December 2013 was retrospectively reviewed. Results 14 children with DSAI occurred in community, median age:15m (range 6d–13y);50%male (7 cases). All patients presented with fever. Addition to fever, the ifrst symptom was skin and soft tissue infections (SSTIs,6 cases) as well as limb and/or joint pain (5 cases). Among children with DSAI, white blood cell count and C-reactive protein values increased signiifcantly. Pyogenic infection site were skin and soft tissue in 12 cases (85.7%), pulmonary (12 cases), bone (4 cases), joint (3 cases), central nervous system (3 case), and pericardium (1 case). SSTIs concurrent with pulmonary infection was found in 10 cases (71.4%). Incision and drainage of skin and soft tissue abscesses were performed in 9 cases, joint debridement and vacuum sealing drainage (VSD) in 3 cases, osteomyelitis debridement and VSD in 3 cases, and closed chest drainage in 3 cases. All cases received vancomycin and/or linezolid treatment, 5 cases supplemented by rifampicin, and intravenous immune globulin therapy was administered in 11 cases. Clinical manifestations were cured or improved in 12 cases (85.7%). Conclusions Clinical diagnosis of DSAI in children needs to be vigilant. SSTIs, bone and joint infections were major precipitating factors. Intravenous immune globulin therapy was supplemented to the application of antibiotics, which might get better clinical outcomes in children.
5.Factors related to contralateral recurrence of primary spontaneous Pneumothorax
Peng YANG ; Qingzhi LI ; Xiao ZHOU ; Deqing GUO ; Xianyou MA ; Hujun ZHU
International Journal of Surgery 2012;39(9):597-599
Objective To investigate the factors associated with contralateral recurrence of primary spontaneous pneumothorax And prosvide referencee for how to prevent primary spontaneous Pneumothrorax with Contralateral recurrence.Methods From January 2006 to December 2011,the clinical follow-up data of 203 patients with primary spontaneous pneumothorax were reviewed.The median follow-up time was 43 months.Results Two hundred and three patients developed 241 recurrences,among which 27 patients had contralateral recurrences.The average time of contralateral recurrence was 20.19 months.Patients with contralateral recurrence of primary spontaneous pneumothorax had smaller age(P < 0.05),lower body weight (P < 0.05) and lower body mass index (P <0.01).All patients with contralateral recurrence of primary spontaneous pneumothorax received surgical treatment and were found bullae during surgery.Three patients had unilateral recurrences of pneumothorax during follow up,with single-stage bilateral video-assisted thoracoscopic surgery for bilateral primary spontaneous pneumothorax.Conclusions Contralateral recurrence of primary spontaneous pneumothorax is more common in patients with small age,low body weight and low body mass index.These patients could perform high-resolution computerized tomographic scan of the lung before surgery.Single-stage bilateral video-assisted thoracoscopic surgery may be considered for these patients with contralateral bullae on high-resolution computerized tomographic scan of the lung to prevent contralateral recurrence of primary spontaneous pneumuothorax.
6.Realization of assist system for the blind by artificial vision
Hujun ZHANG ; Jianwen GU ; Zhengkui GUO ; Weiqi HE ; Xiaokai LI
Chinese Medical Equipment Journal 2004;0(08):-
This paper introduces an assist system for the blind.It utilizes ultrasonic to measure the distance and speed.Then the distance signal is converted to position of slip block and the speed signal is converted to tone.The main function of this sytem is to assist the blind to determine distance and speed of objects.It is practical,Simple and inexpensive.
7.Circulation assist in the radical operation of retro-peritoneal malignancy with the inferior vena cava thrombotic involvement.
Jin WANG ; Feng XIAO ; Mingli ZHANG ; Naiqing SONG ; Liang TAO ; Hujun CUI ; Hongyi CHEN ; Yinglu GUO
Chinese Journal of Surgery 2002;40(2):127-129
OBJECTIVETo discuss the key role of various mode of circulation assist in the radical operation of retro-peritoneal malignancy with the inferior vena cava thrombotic involvement.
METHODS>From the June 1999 to the March 2001, 6 patients with retro-peritoneal malignancy with thrombosis involving the inferior vena cava, were completely resected with various mode of circulation assist.
RESULTSAll the patients operated have good outcomes and follow-up (1 - 20 months) except one death 1 month after operation.
CONCLUSIONAccording to the various types of tumor thrombi, individualized and technically feasible circulation assist mode should be utilized to achieve the satisfactory outcomes.
Aged ; Assisted Circulation ; Humans ; Male ; Middle Aged ; Retroperitoneal Neoplasms ; blood supply ; surgery ; Surgical Procedures, Operative ; Vena Cava, Inferior ; surgery

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