Objective:To analyze the research progress and hotspots in the field of healthcare data security in China, so as to provide a theoretical basis for the safe application of healthcare big data.Methods:A systematic search of the literature in the field of healthcare data security was conducted by using bibliometric methods. The search was performed on the China Knowledge Network, the WIPO Chinese Science and Technology Journal Full-text Database, and the Wanfang Data Knowledge Service Platform from the establishment of the databases to Decembe 2023. Descriptive analysis and high-frequency keywords clustering analysis were conducted.Results:A total of 714 eligible articles were included. Research in the field of healthcare data security emerged since 2002, with the scope of the field expanding since then. There was a surge in publications after 2018. Through the clustering analysis of high-frequency keywords, it was found that current research on healthcare data security mainly focused on six major research hotspots: cross-domain data security sharing, data security and privacy protection, information security technology research, patients′ personal information management and privacy protection, mobile healthcare, and remote healthcare.Conclusions:The research focus in the field of healthcare data security is currently concentrated on six major aspects, including cross-domain data security sharing. It is recommended to strengthen interdisciplinary cooperation, optimize technical frameworks, further innovate data security governance methods, strengthen data security applications, and vigorously cultivate composite talents, so as to promote the research and development of China′s healthcare data security field.

Objective:To analyze the research progress and hotspots in the field of healthcare data security in China, so as to provide a theoretical basis for the safe application of healthcare big data.Methods:A systematic search of the literature in the field of healthcare data security was conducted by using bibliometric methods. The search was performed on the China Knowledge Network, the WIPO Chinese Science and Technology Journal Full-text Database, and the Wanfang Data Knowledge Service Platform from the establishment of the databases to Decembe 2023. Descriptive analysis and high-frequency keywords clustering analysis were conducted.Results:A total of 714 eligible articles were included. Research in the field of healthcare data security emerged since 2002, with the scope of the field expanding since then. There was a surge in publications after 2018. Through the clustering analysis of high-frequency keywords, it was found that current research on healthcare data security mainly focused on six major research hotspots: cross-domain data security sharing, data security and privacy protection, information security technology research, patients′ personal information management and privacy protection, mobile healthcare, and remote healthcare.Conclusions:The research focus in the field of healthcare data security is currently concentrated on six major aspects, including cross-domain data security sharing. It is recommended to strengthen interdisciplinary cooperation, optimize technical frameworks, further innovate data security governance methods, strengthen data security applications, and vigorously cultivate composite talents, so as to promote the research and development of China′s healthcare data security field.

Objective:To systematically evaluate the clinical effect of anodized implants and sandblasted, large-grit, acid-etched (SLA) implants in the recent 10 years, so as to provide a reference for the selection and evaluation of implants.Methods:The data from Pubmed, Cochrane Library, Embase, CNKI, and Wanfang Data database from January 2010 to April 2020 were searched, to find clinical studies on anodized and SLA implants. According to the inclusion and exclusion criteria, literature was strictly screened, and data was extracted. Included studies were evaluated by using the methodological index for non-randomized studies (MINORS) and were analyzed by Stata14.0. The outcome of interest was cumulative survival rate (CSR) and marginal bone loss (MBL). Heterogeneity and publication bias among included literature was evaluated comprehensively.Results:A total of 22 articles, including 6 276 anodized implants, were collected for the analysis of anodized implants. Meta-analysis of proportions showed that anodized implants CSR were 98% (95% CI: 97%-98%, P<0.05) in total, at 5 years were 98% (95% CI: 98%-99%, P<0.05), and at 10 years were 97% (95% CI: 96%-98%, P<0.05). MBL change was 1.02 mm (95% CI: 0.69-1.34, P<0.05) in total. A total of 17 articles, including 4 567 SLA implants, were collected for the analysis of SLA implants. Meta-analysis of proportions showed that SLA implants CSR were 99% (95% CI: 98%-100%, P<0.05) in total, 99% at 5 years (95% CI: 98%-100%, P<0.05), and 99% at 10 years (95% CI: 97%-100%, P<0.05). MBL change was 0.69 mm (95% CI: 0.44-0.95, P<0.05) in total. The results of the above two studies were tested for bias ( P>0.05), indicating no significant publication bias. Conclusions:Meta-analysis suggested that SLA implants have higher CSR and lower MBL than anodized implants.

Objective:To analysis effectiveness of the "14 plus 7 day quarantine" and "nucleic acid plus total antibody testing" strategy (combined screening strategy) for screenin the imported patients with COVID-19 in Xiamen.Methods:The study populations were overseas travelers arriving in Xiamen from March 17 to December 31, 2020, and overseas travelers who had quarantine outside Xiamen for less than 21 days from July 18 to December 31, 2020. Data were collected and analyzed on the timing of detection, pathways, and test results of the imported patients with COVID-19 after implementing combined screening strategy.Results:A total of 304 imported patients with COVID-19 were found from 174 628 overseas travelers and 943 overseas travelers from other cities. A total of 163 cases (53.6%) were diagnosed by multitime, multisite intensive nucleic acid testing after positive finding in total antibody testing. Among them, 27 (8.9%) were first positive for nucleic acid in 14 plus 7 day quarantine and 136 were first positive for nucleic acid in 14-day quarantine. Only 8 of these individuals were tested positive for nucleic acid after positive total antibody testing. The other 128 individuals were tested positive for nucleic acid after being negative for average 2.3 times (maximum of 6 times). Aditional 155 cases might be detected by using the combined "14 plus 7 day quarantine" and " nucleic acid plus total antibody testing" strategy compared with "14-day quarantine and nucleic acid testing" strategy, accounting for 51.0% of the total inbound infections. So the combined screening strategy doubled the detection rate for imported patients with COVID-19. No second-generation case caused by overseas travelers had been reported in Xiamen as of February 26, 2021.Conclusions:Xiamen's combined screening strategy can effectively screen the imported patients with COVID-19 who were first positive for nucleic acid after 14 day quarantine. Compared with "14 day quarantine and nucleic acid testing", the combined screening strategy improved detection rate and further reduced the risk of the secondary transmission caused by the imported patients with COVID-19.