1.Progress of research into the zebrafish(Danio rerio)depression model
Biyu GUO ; Huiluan YANG ; Yifan CHEN ; Xiaomi YANG ; Zheng YAO ; Yu MAO
Acta Laboratorium Animalis Scientia Sinica 2025;33(2):275-287
The zebrafish is characterized by its rapid reproductive cycle,transparent embryonic body in the early developmental stages,high genetic and physiological homology with humans,and low breeding costs.These advantages make it a valuable tool that complements mammalian models of depression.The zebrafish has emerged as a promising model organism for studying mental illnesses owing to its unique biological characteristics and the diverse method available for establishing depression models using this species.This article aims to provide a comprehensive review of zebrafish depression model establishment method,evaluation criteria,advantages,and limitations.
2.Progress of research into the zebrafish(Danio rerio)depression model
Biyu GUO ; Huiluan YANG ; Yifan CHEN ; Xiaomi YANG ; Zheng YAO ; Yu MAO
Acta Laboratorium Animalis Scientia Sinica 2025;33(2):275-287
The zebrafish is characterized by its rapid reproductive cycle,transparent embryonic body in the early developmental stages,high genetic and physiological homology with humans,and low breeding costs.These advantages make it a valuable tool that complements mammalian models of depression.The zebrafish has emerged as a promising model organism for studying mental illnesses owing to its unique biological characteristics and the diverse method available for establishing depression models using this species.This article aims to provide a comprehensive review of zebrafish depression model establishment method,evaluation criteria,advantages,and limitations.
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