ObjectiveTo systematically evaluate the public health governance capacity of 40 cities in Jiangsu, Zhejiang, and Anhui Provinces, providing a scientific evaluation basis for building a "Healthy Yangtze River Delta". MethodsA comprehensive collection of policy documents, public information reports, and research literature related to public health governance capacity in Jiangsu, Zhejiang, and Anhui Provinces was conducted, totaling 6 920 policy documents, 1 720 information reports, and 1 200 literature pieces. Based on the evaluation standards for an appropriate public health system established by the research team, the basic status of public health governance capacity was assessed to identify the strengths and weaknesses of the 40 cities. ResultsIn 2022, the public health governance capacity score for the 40 cities in Jiangsu, Zhejiang, and Anhui Provinces was (562.5±38.0) points. In terms of specific areas, the emergency response field received the highest score of (791.4±49.7) points, while the chronic disease prevention and control field received the lowest score of (368.2±29.6) points. The Jiangsu-Zhejiang-Anhui region has largely achieved the strategic priority of health, gradually improved public health legal regulations, and established a basic organizational framework with a solid foundation for information and data infrastructure. However, challenges still need to be addressed, such as unstable government funding for public health, unclear departmental responsibilities, and barriers to information interoperability. ConclusionThe public health governance capacity of the 40 cities in Jiangsu, Zhejiang, and Anhui Province has been at a moderate level, but disparities have still existed across regions and fields. In the future, while continuing to deepen existing advantages, it is essential to accurately identify the causes of problems, establish a long-term and stable investment mechanism, enhance information connectivity mechanisms, further clarify departmental responsibilities, and promote the achievement of the "Healthy Yangtze River Delta" goal.

Objective:To compare the effects of 8 weeks of aerobic exercise(AE),resistance exercise(RE)and com-bined exercise(CE)on cardiac function,hemodynamics and vascular stiffness in young women with obesity,and to provide theoretical and practical basis for exercise prescription in this population.Method:Forty-seven women with obesity(body fat percentage≥30％)were screened and randomly divided in-to AE,RE and CE group.Exercise intervention consisted of 8 weeks,60 min per session,3 sessions per week.The AE group exercised on a running platform at 70％—75％of the heart rate reserve for 50 min.The RE group completed squats,bench presses and pull-ups sequentially at 75％of the 1 repetition maximum for 10 reps per set,with a 2 min break between sets and 2 min for the change of the movement interval.The CE group performed 25min of resistance training followed by 25min of aerobic training with the same content and intensity as the AE and RE exercise group.Changes in body composition,cardiac function,hemodynam-ics and vascular stiffness were detected before,during and after exercise using a dual-energy X-ray detector,color Doppler ultrasound and arterial stiffness detector.Result:Body fat percentage decreased significantly in all three groups after 8 weeks of exercise compared to pre-exercise(P<0.05).Lean mass significantly decreased in the AE group(P=0.02)at week 4,whereas in-creased significantly in the RE and CE groups at week 8 compared to baseline and exercise(P<0.05).Left ventricular end-diastolic volume(P<0.01),stroke volume(P<0.01),and short-axis foreshortening rate(AE:P<0.01,RE:P=0.01,CE:P=0.047)increased significantly in all three groups after exercise compared to pre-exer-cise.Peak blood flow velocity(AE:P=0.04,CE:P<0.01)and blood flow shear(AE:P=0.01,CE:P<0.01)were significantly higher in the AE and CE groups than in the pre-exercise period,and only the increase in Wall shear stress was statistically significant in the RE group(P=0.02).The left and right brachial-ankle pulse wave conduction velocity(baPWV)of the AE group decreased significantly after 8 weeks of exercise(P<0.05).BaPWV of the RE group did not change significantly(P>0.05).The right baPWV of the CE group de-creased gradually with the increase of the duration of exercise,and the decrease appeared to be statistically significant in the 8 weeks(P=0.03).Conclusion:Eight weeks of aerobic,resistance and combined exercise all improved body composition,cardiac function and hemodynamic indices in young women with obesity.Aerobic and combined exercise not only re-duced body fat but also baPWV.Both combined and resistance exercise increased muscle mass,and resistance exercise had no effect on baPWV in young women with obesity.

Objective:To compare the effects of 8 weeks of aerobic exercise(AE),resistance exercise(RE)and com-bined exercise(CE)on cardiac function,hemodynamics and vascular stiffness in young women with obesity,and to provide theoretical and practical basis for exercise prescription in this population.Method:Forty-seven women with obesity(body fat percentage≥30％)were screened and randomly divided in-to AE,RE and CE group.Exercise intervention consisted of 8 weeks,60 min per session,3 sessions per week.The AE group exercised on a running platform at 70％—75％of the heart rate reserve for 50 min.The RE group completed squats,bench presses and pull-ups sequentially at 75％of the 1 repetition maximum for 10 reps per set,with a 2 min break between sets and 2 min for the change of the movement interval.The CE group performed 25min of resistance training followed by 25min of aerobic training with the same content and intensity as the AE and RE exercise group.Changes in body composition,cardiac function,hemodynam-ics and vascular stiffness were detected before,during and after exercise using a dual-energy X-ray detector,color Doppler ultrasound and arterial stiffness detector.Result:Body fat percentage decreased significantly in all three groups after 8 weeks of exercise compared to pre-exercise(P<0.05).Lean mass significantly decreased in the AE group(P=0.02)at week 4,whereas in-creased significantly in the RE and CE groups at week 8 compared to baseline and exercise(P<0.05).Left ventricular end-diastolic volume(P<0.01),stroke volume(P<0.01),and short-axis foreshortening rate(AE:P<0.01,RE:P=0.01,CE:P=0.047)increased significantly in all three groups after exercise compared to pre-exer-cise.Peak blood flow velocity(AE:P=0.04,CE:P<0.01)and blood flow shear(AE:P=0.01,CE:P<0.01)were significantly higher in the AE and CE groups than in the pre-exercise period,and only the increase in Wall shear stress was statistically significant in the RE group(P=0.02).The left and right brachial-ankle pulse wave conduction velocity(baPWV)of the AE group decreased significantly after 8 weeks of exercise(P<0.05).BaPWV of the RE group did not change significantly(P>0.05).The right baPWV of the CE group de-creased gradually with the increase of the duration of exercise,and the decrease appeared to be statistically significant in the 8 weeks(P=0.03).Conclusion:Eight weeks of aerobic,resistance and combined exercise all improved body composition,cardiac function and hemodynamic indices in young women with obesity.Aerobic and combined exercise not only re-duced body fat but also baPWV.Both combined and resistance exercise increased muscle mass,and resistance exercise had no effect on baPWV in young women with obesity.

Objective:To investigate the application value of aortic dissection detection risk score (ADD-RS) combined with D-dimer (DD) in the early diagnosis of acute aortic dissection (AAD).Methods:The clinical data of 70 patients with suspected aortic dissection detection admitted to The Second Hospital of Jiaxing from August 2019 to April 2020 were collected. All patients were scored using the ADD-RS, and grouped according to the scoring results. The sensitivity and specificity of ADD-RS plus DD in the early diagnosis of AAD were calculated. The areas under the receiver operating characteristic (ROC) curves that were plotted for drADD-RS plus DD versus DD alone to screen AAD were compared to evaluate efficacy. Results:CT angiography results showed that among 70 patients with suspected AAD, 29 patients had AAD and 41 patients had no AAD. A total of 21 patients were scored 0, 41 patients were scored > 1, and 8 patients were scored > 0. ADD-RS > 0 had an overall sensitivity of 79.31% and a specificity of 36.59% for AAD diagnosis. DD test results had an overall sensitivity of 86.20% and a specificity of 36.50% for AAD diagnosis. The area under the ROC curve of ADD-RS = 0 plus DD-negative result and the area under the ROC curve of DD-negative result alone in ruling out AAD were 0.885 with 95% CI (0.786-0.949) and 0.787 with 95% CI (0.673-0.876), respectively. The difference between the two groups was statistically significant ( P = 0.024). Conclusion:Compared with DD-negative result alone, the ADD-RS = 0 plus DD-negative result strategy offers greater specificity to rule out AAD. The combined strategy has a greater efficacy in ruling out AAD. However, a multi-center study involving a large sample is required for in-depth evaluation.