Objective:To construct a personalized service platform based on Internet of Things technique of medical equipment for rehabilitation information,so as to analyze the application effect of that in the management for rehabilitation information of patients.Methods:Based on the Internet of Things technique of medical equipment,a personalized service platform was constructed to conduct intelligent management for rehabilitation information of patients through sensor technique,wireless communication technique and big data analysis technique.A total of 112 patients who received treatment in the department of rehabilitation medicine of Dushan Hospital,Nanyang City Hospital of Traditional Chinese Medicine from February to December 2023 were selected,and they were divided into control group which adopted conventional platform to manage rehabilitation information,and observation group which adopted personalized service platform based on IoTs technique of medical equipment for rehabilitation information to manage rehabilitation information,with 56 cases in each group.A self-made questionnaire was used to investigate the satisfaction of patients of two groups for the service platform of rehabilitation information,and the acceptance scores of maintainers for platform,relevant operators,doctors and nurses for different service platform.The service efficiency and success of rehabilitation treatment of different service platforms were compared.Results:53 patients satisfied for the service platform of rehabilitation information(94.64%)in the observation group,which was higher than that in the control group,and the difference was statistically significant(x2=13.187,P＜0.05).The scores of convenience,flexibility and continuity of patients of observation group were respectively(94.74±3.36),(94.57±4.12)and(93.65±4.02)for the platform,which were higher than those of control group,and the differences were statistically significant(t=14.279,13.604,13.553,P＜0.05).The acceptance scores of maintainers for platform,relevant operators,doctors and nurses were respectively(91.69±2.11),(94.52±3.65),(93.87±4.58)and(94.74±3.36)for the personalized service platform for rehabilitation information of the observation group,which were higher than those in the control group,and the differences were statistically significant(t=15.280,13.236,12.373,14.279,P＜0.05).The waiting time,appointment time and treatment cycle of patients in observation group were respectively(4.65±2.01)min,(3.21±1.03)d and(13.02±1.02)months,which were shorter than those of control group,and the differences were statistically significant(t=9.768,11.401,12.300,P＜0.05).Conclusion:The personalized service platform based on the IoTs technique of medical equipment for rehabilitation information can take doctors to timely adjust rehabilitation programs by combining the dynamic changes of patients'information,and formulate targeted rehabilitation guidance,and provide effective rehabilitation treatment for patients,and reduce waiting time of patient,and shorten the rehabilitation cycle.

Objective To investigate the mechanism by which angiopoietin-like protein 8(ANGPTL8)regulates vascular smooth muscle cell(VSMCs)apoptosis.Methods An in vitro abdominal aortic aneurysm cell model was established by stimulating human VSMCs(HUSMCs)with angiotensin Ⅱ(AngⅡ).Stable ANGPTL8 knockdown and over-expression VSMC cell strains were generated using lentiviral transfection.TUNEL staining was used to de-tect apoptosis.Western blot analysis was performed to measure the protein expression of ANGPTL8,caspase9,caspase3,Bcl-2,Bax,p53,and PUMA,while RT-qPCR was used to assess mRNA expression of ANGPTL8,Bcl-2 and Bax.Results AngⅡ significantly induced ANGPTL8 expression in HVSMCs in a time-and dose-de-pendent manner(P＜0.05).ANGPTL8 knockdown significantly reduced the expression of apoptosis-related proteins caspase9,caspase3,and Bax,while increased the expression of the anti-apoptotic protein Bcl-2(P＜0.05).Con-versely,ANGPTL8 over-expression markedly induced HVSMCs apoptosis,which was significantly suppressed by treatment with the p53 pathway inhibitor pifithrin-α(PFT-α).Conclusions ANGPTL8 may promote VSMC apop-tosis by activation of p53 signaling pathway.

Objective:To construct a personalized service platform based on Internet of Things technique of medical equipment for rehabilitation information,so as to analyze the application effect of that in the management for rehabilitation information of patients.Methods:Based on the Internet of Things technique of medical equipment,a personalized service platform was constructed to conduct intelligent management for rehabilitation information of patients through sensor technique,wireless communication technique and big data analysis technique.A total of 112 patients who received treatment in the department of rehabilitation medicine of Dushan Hospital,Nanyang City Hospital of Traditional Chinese Medicine from February to December 2023 were selected,and they were divided into control group which adopted conventional platform to manage rehabilitation information,and observation group which adopted personalized service platform based on IoTs technique of medical equipment for rehabilitation information to manage rehabilitation information,with 56 cases in each group.A self-made questionnaire was used to investigate the satisfaction of patients of two groups for the service platform of rehabilitation information,and the acceptance scores of maintainers for platform,relevant operators,doctors and nurses for different service platform.The service efficiency and success of rehabilitation treatment of different service platforms were compared.Results:53 patients satisfied for the service platform of rehabilitation information(94.64%)in the observation group,which was higher than that in the control group,and the difference was statistically significant(x2=13.187,P＜0.05).The scores of convenience,flexibility and continuity of patients of observation group were respectively(94.74±3.36),(94.57±4.12)and(93.65±4.02)for the platform,which were higher than those of control group,and the differences were statistically significant(t=14.279,13.604,13.553,P＜0.05).The acceptance scores of maintainers for platform,relevant operators,doctors and nurses were respectively(91.69±2.11),(94.52±3.65),(93.87±4.58)and(94.74±3.36)for the personalized service platform for rehabilitation information of the observation group,which were higher than those in the control group,and the differences were statistically significant(t=15.280,13.236,12.373,14.279,P＜0.05).The waiting time,appointment time and treatment cycle of patients in observation group were respectively(4.65±2.01)min,(3.21±1.03)d and(13.02±1.02)months,which were shorter than those of control group,and the differences were statistically significant(t=9.768,11.401,12.300,P＜0.05).Conclusion:The personalized service platform based on the IoTs technique of medical equipment for rehabilitation information can take doctors to timely adjust rehabilitation programs by combining the dynamic changes of patients'information,and formulate targeted rehabilitation guidance,and provide effective rehabilitation treatment for patients,and reduce waiting time of patient,and shorten the rehabilitation cycle.