1.Response to the letter to the editor: Predicting residual neurologic deficits using the Spinal Infection Treatment Evaluation score after surgery for thoracic and lumbar spinal epidural abscess: a retrospective study in Taiwan
Jian-Jiun CHEN ; Hsi-Hsien LIN ; Po-Hsin CHOU ; Shih-Tien WANG ; Chien-Lin LIU ; Yu-Cheng YAO
Asian Spine Journal 2026;20(2):405-406
2.Predicting residual neurologic deficits using the Spinal Infection Treatment Evaluation score after surgery for thoracic and lumbar spinal epidural abscess: a retrospective study in Taiwan
Jian-Jiun CHEN ; Hsi-Hsien LIN ; Po-Hsin CHOU ; Shih-Tien WANG ; Chien-Lin LIU ; Yu-Cheng YAO
Asian Spine Journal 2026;20(2):255-263
Methods:
A total of 45 patients diagnosed with de novo thoracic or lumbar SEA who underwent posterior-only surgical decompression between 2005 and 2014, with a minimum postoperative follow-up of 2 years, were included. Patients were stratified based on the presence or absence of postoperative residual ND, and neurological function was assessed immediately after surgery and at the final followup using the Frankel grading system. SITE scores, along with clinical and radiological data associated with residual ND, were collected. Logistic regression and receiver operating characteristic (ROC) curve analyses were performed to identify significant predictors.
Results:
Patients with residual ND had significantly lower SITE scores than those without residual ND (4.3±1.3 vs. 7±1.8, p<0.0001). Multivariate analysis identified the SITE score as an independent predictor (odds ratio, 2.70; p=0.012). ROC analysis showed that a SITE score ≤6 predicted residual ND with 73.3% sensitivity and 100% specificity, with an area under the curve of 0.877 (p<0.001). Other significant predictors included cauda equina syndrome and a shorter symptom-to-surgery interval, both of which were associated with a higher risk of residual ND.
Conclusions
The SITE score is a reliable and independent predictor of residual ND after surgery for SEA. SITE scores <6 indicate a significantly higher risk of postoperative ND.
3.Expandable Intravertebral Titanium Implants for Thoracolumbar Burst Fractures Without Neurological Deficits
Chi-Yung YEUNG ; Ming-Chau CHANG ; Po-Hsin CHOU ; Shih-Tien WANG ; Hsi-Hsien LIN ; Yu-Cheng YAO ; Chien-Lin LIU
Journal of Minimally Invasive Spine Surgery and Technique 2024;9(2):160-169
Objective:
A thoracolumbar burst fracture (TLBF) is defined as the failure of the anterior and middle columns of the vertebra due to high-energy trauma, such as motor vehicle collisions and falls from heights. Debate has continued for decades regarding the standard treatment, especially for TLBFs without neurological deficits (TLBF-WONDs). The aim of this study was to understand the role of expandable intravertebral titanium implants (EITIs) in treating TLBF-WONDs.
Methods:
We included patients aged 18–65 years who presented at our hospital Emergency Department with severe back pain (visual analogue scale [VAS] score ≥ 8), were neurologically intact, were diagnosed with TLBF-WOND by either computed tomography or magnetic resonance imaging, underwent percutaneous bilateral transpedicular EITI implantation, and were followed-up for ≥12 months. Radiological and clinical outcomes were analyzed.
Results:
Thirty patients satisfied the study inclusion criteria, including 9 men and 21 women, with an average age of 48.2 years. Thirteen A3 and 17 A4 burst fractures were included. The mean duration of hospitalization was 3.3 days. The mean follow-up period was 4.4 years. All patients exhibited significant improvements in radiographical (anterior, middle, and posterior vertebral heights); vertebral kyphotic angle (p<0.001); and functional outcomes (VAS and Oswestry Disability Index scores, p<0.001). One case of cement leakage into the paraspinal muscle was observed; however, no major complications occurred.
Conclusion
Percutaneous bilateral transpedicular EITI placement with cement augmentation under local anesthesia may be an effective strategy for the treatment of high-energy traumatic TLBFs with neurological integrity.
4.Bifocal pain in nummular headache: A clinical analysis and literature review
Yi-Ting Chen ; Chiu-Hsien Lin ; Tzu-Hui Li ; Lian-Hui Lee ; Wei-Hsi Chen
Neurology Asia 2013;18(1):59-63
Background: Nummular headache is a new category of primary headache disorder characterized by
consistent location, size, and shape of painful areas. The pathogenesis is uncertain. Bifocal painful
areas are rare manifestations but may expand the clinical diversity of nummular headache. Methods:
The clinical characteristics of 5 bifocal nummular headache patients were reported and those of 11
patients in previous studies were reviewed. Bifocal nummular headache was classifi ed into two types.
Type I was defi ned as a simultaneous activation of two painful areas while type II was defi ned as
two painful areas occurring in different times. Results: All 16 patients were female, with mean age
of onset and initial presentation of 54.7 years and 58.2 years, respectively. There were seven type
I and nine type II patients. The parietal area, especially the tuber parietale, was the leading site of
involvement in both types of patients. The shape and size of painful areas were also similar between
these two groups. There was an equal frequency of ipsilateral and contralateral painful areas. The pain
intensity was similar in both types of patients but was milder in new painful areas than in previous
painful areas in type II patients.
Conclusions: Bifocal nummular headache suggests a central role of nummular headache but does not
debunk the peripheral theory of nummular headache. The accumulated fi ndings in bifocal NH patients
do not support a generalization of pain occurrence or a reproduction of local process of epicranial
neuralgia at multiple sites in nummular headache.

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