1.Analysis of clinical characteristics and prognostic factors of 51 patients with multiple sclerosis in Suzhou area
Benyu QIAO ; Xiaoke WU ; Wenli SONG ; Keru LI ; Houde LI ; Yu JIANG ; Jinru ZHANG ; Xiaodong XU ; Dongqin CHEN ; Yongjun CAO ; Yanlin ZHANG
Chinese Journal of Immunology 2025;41(3):680-685
Objective:To explore clinical characteristics of multiple sclerosis(MS)patients in Suzhou,and to analyze main factors affecting their prognosis.Methods:General data,clinical symptoms,cerebrospinal fluid and imaging examinations of 51 MS patients admitted to Department of Neurology of the Second Hospital of Soochow University from July 31,2009 to July 31,2021 were retrospectively analyzed,and main factors affecting their prognosis were discussed.Results:Average age of onset of 51 MS patients was(43.3±15.6)years old,female accounted for 56.9%,male/female=1/1.3.Adult onset MS(AOMS)accounted for 62.8%,male/female=1/1.7;late onset MS(LOMS)accounted for 37.2%,male/female=1/0.9.Relapsing remitting MS(RRMS)accounted for 76.5%,and chronic onset accounted for 60.8%.Average annual recurrence rate was 8.8%.The first symptoms were numbness and weakness of limbs.Dizziness and numbness were more common in patients without recurrence after diagnosis of MS,and limb weak-ness and numbness were more common in patients with recurrence.Among lesions of MRI,62.7%(32/51)of periventricular involve-ment,52.9%(27/51)of spinal cord involvement,51.0%(26/51)of infratentorial involvement.Proportion of subtentorial and spinal cord(cervical,thoracic)involved were significantly higher in patients with recurrent MS than without recurrence.Values of albumin,IgG,IgA and IgM in cerebrospinal fluid increased with increase of recurrence times.EDSS score of male was higher than female,and LOMS score was higher than AOMS.MS patients without relapse had a low EDSS score,and median EDSS score at current follow-up was 0(0,1.00)score.MS score with relapse was relatively high,and median EDSS score at current follow-up was 2.75(0.25,7.25)score.Conclusion:MS patients with chronic onset are more common,with a high proportion of LOMS,and proportion of males increases with increasing age of onset.High EDSS score at first onset,cervical,thoracic and subtentorial lesions,increased values of cerebrospinal fluid albumin,IgG,IgA,IgM,age at first onset(50+years old),male associate with poor MS prognosis.
2.Analysis of clinical characteristics and prognostic factors of 51 patients with multiple sclerosis in Suzhou area
Benyu QIAO ; Xiaoke WU ; Wenli SONG ; Keru LI ; Houde LI ; Yu JIANG ; Jinru ZHANG ; Xiaodong XU ; Dongqin CHEN ; Yongjun CAO ; Yanlin ZHANG
Chinese Journal of Immunology 2025;41(3):680-685
Objective:To explore clinical characteristics of multiple sclerosis(MS)patients in Suzhou,and to analyze main factors affecting their prognosis.Methods:General data,clinical symptoms,cerebrospinal fluid and imaging examinations of 51 MS patients admitted to Department of Neurology of the Second Hospital of Soochow University from July 31,2009 to July 31,2021 were retrospectively analyzed,and main factors affecting their prognosis were discussed.Results:Average age of onset of 51 MS patients was(43.3±15.6)years old,female accounted for 56.9%,male/female=1/1.3.Adult onset MS(AOMS)accounted for 62.8%,male/female=1/1.7;late onset MS(LOMS)accounted for 37.2%,male/female=1/0.9.Relapsing remitting MS(RRMS)accounted for 76.5%,and chronic onset accounted for 60.8%.Average annual recurrence rate was 8.8%.The first symptoms were numbness and weakness of limbs.Dizziness and numbness were more common in patients without recurrence after diagnosis of MS,and limb weak-ness and numbness were more common in patients with recurrence.Among lesions of MRI,62.7%(32/51)of periventricular involve-ment,52.9%(27/51)of spinal cord involvement,51.0%(26/51)of infratentorial involvement.Proportion of subtentorial and spinal cord(cervical,thoracic)involved were significantly higher in patients with recurrent MS than without recurrence.Values of albumin,IgG,IgA and IgM in cerebrospinal fluid increased with increase of recurrence times.EDSS score of male was higher than female,and LOMS score was higher than AOMS.MS patients without relapse had a low EDSS score,and median EDSS score at current follow-up was 0(0,1.00)score.MS score with relapse was relatively high,and median EDSS score at current follow-up was 2.75(0.25,7.25)score.Conclusion:MS patients with chronic onset are more common,with a high proportion of LOMS,and proportion of males increases with increasing age of onset.High EDSS score at first onset,cervical,thoracic and subtentorial lesions,increased values of cerebrospinal fluid albumin,IgG,IgA,IgM,age at first onset(50+years old),male associate with poor MS prognosis.
3.Research on the Evaluation System of Clinical Value of Digital Radiography.
Fan BI ; Bin LI ; Houde CAO ; Haisheng HU ; Wenyong TU
Chinese Journal of Medical Instrumentation 2019;43(2):146-149
OBJECTIVE:
To establish a set of evaluation system of digital radiography clinical value and provide foundation for the maturity assessment of digital radiography.
METHODS:
The evaluation system of clinical value of digital radiography was established by literature survey,expert consultation,and percentage weight method.
RESULTS:
The expert authority coefficients were 0.81 and 0.88,respectively.After two rounds of consultation,variation coefficients of each item ranged from 0 to 0.207,and the coefficient coordination were 0.599.The index system consisted of 5 first-level indexes and 12 second-level indexes.The weights of first-level indexes such as image quality,safety,usability,economic and social indicators share of the weight are 0.298,0.294,0.199,0.121 and 0.088 respectively.
CONCLUSIONS
A completed and scientific evaluation system was established,which provides a scientific assessment tool for clinical value of digital radiography.
Delphi Technique
;
Radiographic Image Enhancement
;
standards
4.MRI Imaging Device Channel Number Acceptance Appraisal Research
Chinese Journal of Medical Instrumentation 2016;40(3):217-220
This paper verifies MRI RF system conformity of the actual channel number and the manufacturer's nominal channel number, and inspects the actual channel number’s effect on the properties of magnetic resonance imaging (MRI). At the same time through detecting the increasing channel number’s relationship with MRI detection system image noise level and the image reconstruction speed, to verify the number of MRI RF system receiver is closely related with SNR, MRI scan time and so on.

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