1.Research progress on the relationship between immune inflammatory indicators and the prognosis of bronchial asthma
Jian DONG ; Honglu ZHENG ; Qingyong CHEN
Journal of Public Health and Preventive Medicine 2026;37(3):138-142
Bronchial asthma is a common heterogeneous disease of airway inflammation, and children are the main susceptible population. Modern medical studies have suggested that bronchial asthma is related to inflammatory response and immune system, and a variety of inflammatory cells are involved in disease progression. In recent years, important progress has been made in the study of immune inflammatory indicators of prognosis, which is of great value for clinical evaluation of treatment effect and prognosis of patients. This paper reviews the application progress of typical immune inflammatory indicators such as cytokines, chemokines, immune cells and their surface molecules, and inflammatory mediators in the role mechanism and prognosis evaluation of bronchial asthma, in order to provide more scientific reference basis for the clinical diagnosis and treatment of bronchial asthma.
2.With 3D-MPRAGE and DWI sequence evaluation of intraplaque hemorrhage before carotid artery stenting
Bin YAO ; Honglu SHI ; Guangbin WANG ; Li YANG ; Xingyue ZHENG
Journal of Practical Radiology 2014;(11):1798-1801
Objective To assess intraplaque hemorrhage before carotid artery stenting (CAS)by use of 3D-MPRAGE and DWI sequence.Methods Thirty-two symptomatic patients who had carotid artery plaque suspected by color Doppler ultrasonography and prepared for CAS underwent 3.0T carotid high-resolution MR scans,including regular sequence,T1-weighted gradient echo three-di-mensional magnetization prepared (3D-MPRAGE ) sequence,diffusion-weighted imaging (DWI ) sequences.According to 3D-MPRAGE sequence hemorrhage and non-hemorrhage groups were divided,and measured the mean ADC values of the two groups, hemorrhage and non-hemorrhage part in the hemorrhage group.Meanwhile preoperative cerebral hemorrhage group underwent brain DWI scans.Independent samples t-test analysis was utilized by SPSS V20.0 statistical software.Results High-resolution MRI dis-played 40 plaques,fourteen hemorrhagic plaques showed by 3D-MPRAGE sequence.The mean ADC values of hemorrhage and no-hemorrhage group were(1 233.5±283.5)× 10 -6 mm2/s,(1 688.9 ± 449.6)× 10 -6 mm2/s respectively,the difference of both was significant (t=3.43,P <0.05).The mean ADC values of hemorrhage and non-hemorrhage parts in the hemorrhage group mean ADC values were (934.0 ± 387.9)× 10-6 mm2/s,(1 313.9 ± 295.0)× 10-6 mm2/s respectively;the difference of both was statistically significant (t=2.92,P < 0.05 ).The difference of mean ADC values between non-hemorrhage part in the hemorrhage group and hemorrhage group was statistically significant (t=2.80,P <0.05).Conclusion 3D-MPRAGE and DWI sequences can be evaluated intraplaque hemorrhage before CAS,and provided a reliable basis for timely clinical interventions to prevent stroke.
3.Application of two fall assessment scales on the elderly patients
Honglu DUAN ; Mei WANG ; Huamei ZHENG
Modern Clinical Nursing 2013;(11):26-28
Objective To reduce the feasibility of combining the two fall assessment scales in nursing patients..Methods Two nurses were assigned to conduct the assessments among 60 senile patients using Morse assessment scale and Hendrich Ⅱassessment scale to screen patients with high-risk fall.Result The number of high-risk patients using Morse assessment scale was larger than that using Hendrich II assessment scale(P<0?05) Conclusions The combined use of Morse fall assessment scale and HendrichⅡfall assessment scale may make up the shortcomings of each other,assess the risk factors and predict the high risk factors.
4.A social survey of patients with spinal cord injury 26 years after Tang Shan earthquake
Jianjun LI ; Hongjun ZHOU ; Genlin LIU ; Songhuai LIU ; Chaonan ZHAO ; Zhongxiang MI ; Zhiru CUI ; Ying ZHENG ; Chunxia HAO ; Zongsheng XIONG ; Honglu MA ; Tianjian ZHOU
Chinese Journal of Rehabilitation Theory and Practice 2005;11(2):110-112
ObjectiveTo investigate the living condition of patients with spinal cord injury (SCI) after Tangshan earthquake.MethodsA questionnaire was designed for the investigation with 41 items including resident environment, income, mood, etc. The faculty of surveillance was composed of trained professionals. 1261 SCI patients living in Tangshan at present, 420 of which live in the sanatoriums and others live in the common families. The patients of four sanatoriums were chosen randomly from fourteen sanatoriums to be investigated in detail, and patients in the common families in two communities, one from city, another from countryside, were also chosen. This investigation was performed in 2003.The results are compared with that of 1988' survey.ResultsGreat improvements in the living condition of SCI patients in Tangshan were shown by the comparison of these two surveys, they were mainly in: the progress in the housing environments (100% SCI patients now live in the specially designed reconstructed houses); better medical services provided (the ratio of wheelchair available from 38.1% to 100%); the majority of the patients in acceptance stage of their disability; the increase of income (21.1% takes up various occupation) with a vigorous spare time; decrease in the common complications with SCI patients; although uremia was still the first death cause of the SCI patients, the percentage was decreased apparently; cardiovascular accident had a higher percentage in the death cause(the second leading cause), implies that the death cause of the SCI survivors had approached the normal person.ConclusionThe improvements reflect the social progress in China. However, still there are some problems to be remained for further solution: the ratio of employment is low; the insurance of living and medical rehabilitation needs further improvement.


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