Avoidant/Restrictive Food Intake Disorder(ARFID)made its diagnostic debut in DSM-5. It often occurs in adolescents and children, and can also develop in adults. It often manifests as clinically significant avoidance or restriction of intake of certain foods resulting in a great impact on the physical and mental health of patients. There is little clinical experience of this disease in China, while nutritional support, cognitive behavioral treatment and drug therapy have been used abroad to have showed some effect. In this article, the patient was diagnosed as ARFID and took olanzapine, sertraline, and tandospirone under the premise of parenteral nutrition, specific dietary regimes, and behavioral restriction to achieve certain clinical effects. The discussion based on this ARFID case may to provide clinical experience and insights for clinical practice.

Objective:This study aims to explore the event-related potentials (ERPs) response to alcohol visual cues and their correlations with subjective craving in patients with alcohol dependence (AD) and to search for brain source regions associated with alcohol craving.Methods:Twenty male inpatients with AD were recruited as alcohol-dependent group and 18 healthy men as the control group. ERPs evoked by visual Oddball paradigm containing alcohol cues were tested in both groups and standardized low-resolution brain electromagnetic tomography (sLORETA) was used for brain source localization of ERPs-P300.Visual Analogue Scale (VAS) and Penn Alcohol Craving Scale (PACS) were used for subjective craving assessment. Difference analysis of ERPs data in two groups was performed by mixed-design analysis of variance. The permutation test was used to analyze the difference between two groups of brain source localization. Spearman correlation analysis was conducted between ERPs data, drinking habits, and scale data.Results:Compared with the control group, the alcohol-dependent group showed significantly longer P300 peak latency ( F=9.32, P=0.004) and higher P300 amplitude ( F=20.59, P<0.01; F=14.74, P<0.01) of Fz/Cz when viewing alcohol cues images, and P300 brain source regions were significantly more active in the bilateral dorsolateral prefrontal cortex and right superior parietal lobule ( P<0.01). In the alcohol-dependent group, alcohol cues images evoked significantly longer P300 peak latency ( F=33.82, P<0.01) and higher P300 amplitude ( F=12.56, P=0.001; F=10.92, P=0.002) of Fz/Cz than fruit images, and P300 brain source regions were significantly more active in the left insular cortex and right parahippocampal gyrus ( P<0.01). The P300 amplitude evoked by alcohol cues was positively correlated with VAS and PACS scores ( r s=0.590, P=0.048; r s=0.780, P<0.01). Conclusion:ERPs evoked by visual alcohol cues may help to objectively evaluate craving-related psychology in patients with AD. The bilateral dorsolateral prefrontal cortex, right inferior parietal lobule, left insular cortex, and right parahippocampal gyrus may be related to alcohol craving.

Objective:To explore the application value of modified Shiquan Dabutang in the treatment of elderly patients with osteoporotic intertrochanteric fractures （OIFs） due to Qi and blood deficiency by observing its impacts on inflammatory and bone metabolism indexes. Method:Ninety-eight elderly patients admitted to our hospital for OIFs of Qi and blood deficiency syndrome from April 2018 to April 2020 were randomized into an observation group （n=49） and a control group （n=49）. Following the proximal femoral nail antirotation （PFNA） fixation， patients in the control group were treated with Guipiwan， while those in the observation group received the modified Shiquan Dabutang. The clinical efficacy， inflammatory and bone metabolism indexes， and complications were compared between the two groups after four weeks of treatment. Result:The levels of such serum indexes as fibroblast growth factor-2 （FGF-2）， osteoprotegerin （OPG）， transforming growth factor-β₁ （TGF-β₁）， β-endorphin （β-EP）， bone-specific alkaline phosphatase （BALP）， and osteocalcin （BGP） in the observation group after treatment were significantly elevated as compared with those in the control group （P<0.05）， whereas the serum tumor necrosis factor-α （TNF-α） and D-dimer （D-D） declined （P<0.05）. The TCM symptom score in the observation group after treatment was obviously lower than that in the control group， while the Harris Hip Score （HHS） was higher （P<0.05）. The overall response rate of the observation group was 93.88% （46/49）， higher than 75.51% （37/49） of the control group （χ²=6.376， P<0.05）. The total incidence of incision infection， deep vein thrombosis of lower limbs， and pulmonary infection in the control group was 24.49% （12/49）， significantly higher than 6.12% （3/49） in the observation group （χ²=6.607， P<0.05）. Conclusion:The modified Shiquan Dabutang is able to alleviate inflammation， regulate bone metabolism， promote bone repair， and reduce the incidence of complications in elderly patients with OIFs due to Qi and blood deficiency.

Avoidant/Restrictive Food Intake Disorder(ARFID)made its diagnostic debut in DSM-5. It often occurs in adolescents and children, and can also develop in adults. It often manifests as clinically significant avoidance or restriction of intake of certain foods resulting in a great impact on the physical and mental health of patients. There is little clinical experience of this disease in China, while nutritional support, cognitive behavioral treatment and drug therapy have been used abroad to have showed some effect. In this article, the patient was diagnosed as ARFID and took olanzapine, sertraline, and tandospirone under the premise of parenteral nutrition, specific dietary regimes, and behavioral restriction to achieve certain clinical effects. The discussion based on this ARFID case may to provide clinical experience and insights for clinical practice.

Objective:This study aims to explore the event-related potentials (ERPs) response to alcohol visual cues and their correlations with subjective craving in patients with alcohol dependence (AD) and to search for brain source regions associated with alcohol craving.Methods:Twenty male inpatients with AD were recruited as alcohol-dependent group and 18 healthy men as the control group. ERPs evoked by visual Oddball paradigm containing alcohol cues were tested in both groups and standardized low-resolution brain electromagnetic tomography (sLORETA) was used for brain source localization of ERPs-P300.Visual Analogue Scale (VAS) and Penn Alcohol Craving Scale (PACS) were used for subjective craving assessment. Difference analysis of ERPs data in two groups was performed by mixed-design analysis of variance. The permutation test was used to analyze the difference between two groups of brain source localization. Spearman correlation analysis was conducted between ERPs data, drinking habits, and scale data.Results:Compared with the control group, the alcohol-dependent group showed significantly longer P300 peak latency ( F=9.32, P=0.004) and higher P300 amplitude ( F=20.59, P<0.01; F=14.74, P<0.01) of Fz/Cz when viewing alcohol cues images, and P300 brain source regions were significantly more active in the bilateral dorsolateral prefrontal cortex and right superior parietal lobule ( P<0.01). In the alcohol-dependent group, alcohol cues images evoked significantly longer P300 peak latency ( F=33.82, P<0.01) and higher P300 amplitude ( F=12.56, P=0.001; F=10.92, P=0.002) of Fz/Cz than fruit images, and P300 brain source regions were significantly more active in the left insular cortex and right parahippocampal gyrus ( P<0.01). The P300 amplitude evoked by alcohol cues was positively correlated with VAS and PACS scores ( r s=0.590, P=0.048; r s=0.780, P<0.01). Conclusion:ERPs evoked by visual alcohol cues may help to objectively evaluate craving-related psychology in patients with AD. The bilateral dorsolateral prefrontal cortex, right inferior parietal lobule, left insular cortex, and right parahippocampal gyrus may be related to alcohol craving.

OBJECTIVE: To compare the clinical therapeutic effect of long-snake moxibustion and ginger-partitioned moxibustion at point on nonspecific low back pain (NLBP) with symptom of cold and dampness. METHODS: A total of 120 patients were randomized into a long-snake moxibustion group, an ashi point group and a waiting for treatment group, 40 cases in each one. Ginger-partitioned moxibustion was applied from Dazhui (GV 14) to Yaoshu (GV 2) of governor vessel in the long-snake moxibustion group, and was applied at point of affected area in the ashi point group, 40 min each time, once every other day and totally 8 times were required. No intervention was adopted in the waiting for treatment group, and after the trial, long-snake moxibustion was applied. Before and after treatment, the visual analogue scale (VAS) scores of rest and activity, the Oswestry disability index (ODI) score and the score of cold and dampness symptom were observed in the 3 groups. RESULTS: Compared before treatment, the VAS scores of rest and activity, the ODI scores and the scores of cold and dampness symptom after treatment were decreased in the long-snake moxibustion group and the ashi point group (<0.05). After treatment, the variations of the above indexes in the long-snake moxibustion group and the ashi point group were larger than those in the waiting for treatment group (<0.05), and the variations of the above indexes in the long-snake moxibustion group were larger than those in the ashi point group (<0.05). CONCLUSION Long-snake moxibustion can effectively improve the pain, dysfunction and the symptom of cold and dampness in patients with nonspecific low back pain, and the improvement is superior to the ginger-partitioned moxibustion at point.
Acupuncture Points ; Humans ; Low Back Pain ; therapy ; Medicine, Chinese Traditional ; Moxibustion