Purpose: Short bowel syndrome (SBS) is a critical condition in pediatric patients. It often results in dependence on parenteral nutrition (PN) and significant morbidity. This study aimed to review pediatric SBS patients from a single center and analyze clinical outcomes based on etiology and anatomical type. Methods: A total of 55 patients diagnosed with SBS at our institution from January 2004 to December 2018 were retrospectively analyzed. Clinical demographics and outcomes including growth and PN dependence were evaluated according to etiology and anatomical type. Results: The predominant cause of SBS was necrotizing enterocolitis (NEC). At the last follow-up, the mean weight-forage (z-score) was –2.00 ± 2.07 and 52.7% of patients were weaned off PN. Catheter-related bloodstream infection and PN-associated liver disease occurred in 36.4% and 20.0% of cases, respectively. Patients with motility disorders exhibited lower weight-for-age and longer durations of PN than those with NEC or intestinal atresia. Additionally, outcomes varied significantly by anatomical type, with type I patients showing higher PN dependence and lower rates of successful weaning off PN than type III patients. Conclusion The study suggests that clinical outcomes in pediatric SBS patients can vary depending on underlying etiology and anatomical type, indicating that tailored interventions might enhance patient outcomes. Further research is needed to identify independent prognostic factors for SBS and improve the quality of life of SBS children.

Purpose: The purpose of this study was to develop website-based learning contents to activate voluntary monitoring and reporting of adverse drug reactions (ADRs) for clinical nurses and to verify their effectiveness.Method: Using a quasi-experimental control group pretest-posttest design with random allocation, a total of 60 nurses with more than 1 year of clinical experience were recruited from a university hospital in Seoul, Korea. A website was developed that provides learning contents including real cases and the latest drug-related knowledge, as well as video lectures. Knowledge on ADR monitoring, self-efficacy, ADR practice behavior, and medication performance ability were measured at 2 weeks after intervention. A small notebook for monitoring ADRs of nurses was given to the control group. Data were analyzed using descriptive statistics, the chi-squared test, and the independent t test using SPSS Statistics Software Version 21.0. Results: The scores of ADR monitoring knowledge, self-efficacy, and ADR monitoring practice in the experimental group significantly increased after the intervention compared with the control group (p < .05). However, there was no significant difference between the two groups in medication performance ability related to ADR monitoring. Conclusion To spread a safety culture in which voluntary ADR monitoring and reporting is activated, it is necessary for clinical nurses to share and communicate ADR-related information and real cases through an open website.