1.Textual research on the evolution of the meridian-zangfu related theory in the Warring States, Qin and Han dynasties.
Xiaohong CHEN ; Dekun LIU ; Ruibin ZHANG ; Yahan ZENG ; Sha YANG ; Shuguang YU
Chinese Acupuncture & Moxibustion 2025;45(3):280-287
The paper reviews the evolution of the theory related to meridians and zangfu organs during the Warring States, Qin and Han dynasties, so as to reveal the rules and value of its development. By analyzing historical documents, especially Zubi Shiyimai Jiujing (Moxibustion Classics of Eleven Meridians of Legs and Arms), Yinyang Shiyimai Jiujing (Moxibustion Classic on Eleven Yin and Yang Meridians), Laoguanshan bamboo medical slips of Han Dynasty and lacquer figure of meridian points, the evolutionary stages, i.e. the germination, development, and maturity of meridian-zangfu theory, are explored. In the time of the Warring States, Qin and Han dynasties, the meridian-zangfu related theory was developed from the germination to the maturity. In the classics of the early time, Zubi Shiyimai Jiujing and Yinyang Shiyimai Jiujing demonstrated the preliminary relationship between meridians and zangfu organs, focusing on the physiological connection and pathogenesis of three yin meridians of foot and zangfu organs. In the literature of Laoguanshan bamboo medical slips of Han Dynasty and lacquer figure of meridian points, the physiological connection between the yin meridians of hand and foot, and five zang organs, as well as the related diseases were further clarified; additionally, the meridian-zangfu theory had been developed in the field of diagnosis and treatment. In the era of Chapter of Meridians in Lingshu (Miraculous Pivot), there were up to 31 descriptions relevant with the connection of meridian distribution and zangfu physiological functions. It marks the construction of the "circular" flow of meridians and the interior-exterior communication of zang and fu organs; and enriches the knowledge in diseases, diagnosis and treatment with meridians and zangfu organs involved. The review on the evolution of the meridian-zangfu theory is conductive to supplementing and improving the development history of this theory of early time, and further recognizing its development rules and value. The maturity of this theoretical system not only links the meridians with the five zang and six fu organs, but also provides an important theoretical basis for the diagnosis and treatment of traditional Chinese medicine.
Meridians
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Humans
;
History, Ancient
;
China
;
History, Medieval
;
History, 19th Century
;
History, 20th Century
;
History, 18th Century
;
History, 17th Century
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History, 16th Century
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Medicine, Chinese Traditional/history*
2.Academic characteristics of acupuncture and moxibustion of Qilu medical masters in Ming and Qing dynasties and its influence on later generations.
Chinese Acupuncture & Moxibustion 2025;45(8):1171-1179
The biography, medical writings and family lineages of Qilu medical masters in the Ming and Qing dynasties were collected and collated, so as to analyze their contributions to expounding acupuncture and moxibustion theories, practicing medical ethics and morals, and academic inheritance in later generations; as well as exploring the valuable guidance to clinical practice of modern acupuncture and moxibustion. ZHAI Liang, YUE Hanzhen, HUANG Yuanyu and LIU Kui were representatives of Qilu masters in the Ming and Qing dynasties. They showed their respects on classics with high inclusion, laid stress on elaboration and innovation in theories and practice of meridians, acupoints and acupuncture technique specially. Based on family heritage and apprenticeship, not only the academic school of acupuncture-moxibustion with regional characteristics had been cultivated, but also the important foundation been laid for the perfection of acupuncture-moxibustion diagnosis and treatment system in later generations. The integration of medical ethics and medical skills showed the spirit of "the benevolence of a doctor". These masters devoted themselves to the collation and research of medical books, collected the classics of medical masters, and wrote a number of easily-learned popular works for clinical application to benefit future generations.
Moxibustion/history*
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Humans
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China
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Acupuncture/education*
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Acupuncture Therapy/history*
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History, 20th Century
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History, 19th Century
3.Study on the impacts of George Soulié de Morant and Paul Ferreyrolles' first paper "L' Acuponcture en Chine vingt siècles avant J.-C. et la réflexothérapie moderne" on the transmission of acupuncture-moxibustion to the West.
Yichao PANG ; Han WANG ; Meyer Elena DE ; Xueling LI ; Kai WU
Chinese Acupuncture & Moxibustion 2025;45(10):1484-1489
In 1929, George Soulié de Morant and Paul Ferreyrolles co-authored their first acupuncture-moxibustion paper titled "L' Acuponcture en Chine vingt siècles avant J.-C. et la réflexothérapie moderne", greatly advancing the development of acupuncture-moxibustion in Europe. Their paper systematically explains the holistic view and the concept of yin-yang balance in traditional Chinese medicine, describes the techniques of acupuncture and moxibustion, innovatively classifies acupuncture-moxibustion as "reflexotherapy", organizes the effects of certain acupuncture points illustrated on human acupoint atlas; and for the first time, it summarizes the correspondence between acupuncture points and Weihe trigger points. In the historical background of the neo-Hippocratic movement, they used the existing theories at that time to explain acupuncture, and adopted the analogical medicine to explore the mechanisms of acupuncture-moxibustion, which gradually initiated the modern era of acupuncture-moxibustion in France. Such research method is conducive to reducing the unfamiliarity of acupuncture-moxibustion among westerners, deepening their understanding of its theories and therapeutic effect, and also integrating it with other medical research. It breaks through the limitations of traditional theories and obtains the self-improvement and progress.
Humans
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Moxibustion/history*
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Acupuncture Therapy/history*
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China
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History, Ancient
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History, 20th Century
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Acupuncture/history*
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Reflexotherapy/history*
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Acupuncture Points
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History, 19th Century
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Medicine, Chinese Traditional/history*
4.The historical evolution of Chinese physiology textbooks.
Yan FENG ; Xiao ZHAI ; Xin WANG ; Feng YANG ; Liang ZHU ; Guo-Chao SUN ; Ning WANG ; Jun ZHANG ; Jing XIAO ; Wei-Wei LIU ; You-Fei GUAN
Acta Physiologica Sinica 2025;77(1):1-12
This article systematically reviews the characteristics and trends of the writing, editing, publication and promotion of physiology textbooks in China from the late 19th century to the present, focusing on the introduction, development and innovation of Chinese physiology textbooks. The development of physiology textbooks in China is divided into four main stages: the introduction and initial development of physiology textbooks from the late 19th century to 1925; the localization and diversification of textbooks from 1926 to 1949, after the establishment of the Chinese Physiological Society; the exploratory phase of textbook construction after the founding of the People's Republic of China from 1949 to 1976; the formation and innovation of the textbook development process from 1977 to the present, following the restoration of the college entrance examination. For each phase, the article not only records the historical development of physiology textbooks, but also analyzes the evolution of their content, writing styles and the interaction with the social and political contexts. The article summarizes the characteristics and experiences of all these four phases. Special attention is given to the comprehensive statistical analysis of physiology textbooks published since the restoration of the college entrance examination and Economic Reform and Opening-up in 1977, revealing the changes in the number, publication trends and academic features of textbooks during this period. Finally, the article presets the future development of physiology textbooks in China, proposing that textbook writing should integrate aspects such as ideological and political education, medical humanities, basic and clinical medicine, health education, scientific research and international exchange and collaboration. The article also advocates for the application of new technologies and methods, such as artificial intelligence, virtual teaching models and knowledge graphs, to support "personalized learning". This research provides a systematic reference for the study of the history of medical education and offers theoretical support for the future innovation of physiology textbook in China.
Humans
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China
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History, 19th Century
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History, 20th Century
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History, 21st Century
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Physiology/education*
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Textbooks as Topic/history*
5.Identification of characteristics, supply channels, and imperial court processing of Arecae Semen in the Qing court.
Feng-Yuan LI ; Hua-Sheng PENG ; Xue-Ling GUAN ; Yan JIN ; Ting YAO ; Yuan YUAN ; Lu-Qi HUANG
China Journal of Chinese Materia Medica 2025;50(11):2924-2930
Qing court records show that Arecae Semen was extensively applied. The royal medical records of the Qing Dynasty document nine types of Arecae Semen, with the Palace Museum preserving seven kinds, totaling twelve cultural relics. Historical documents and physical artifacts corroborate each other, providing evidence for the study of the supply channels and court processing of Arecae Semen in the Qing court. According to relevant Qing court archival records, the sources of Arecae Semen used in the imperial court were diverse, including tributes from foreign countries such as Vietnam and Gurkha, annual tributes from local governments in Guangdong, gifts from close aides, and commodities purchased by the Imperial Household Department from civilian shops. The imperial physicians of the Qing court placed great emphasis on the specifications of Arecae Semen slices and were extremely meticulous about their processing. The variety of Arecae Semen slices used in the Qing palace exceeded those recorded in the botanical texts of the era. Compared with the commonly used processing methods for Arecae Semen in the Qing Dynasty, the imperial physicians adjusted the properties and efficacy of the herbs through different processing techniques, based on the patient's condition, constitution, and other factors, in order to meet the clinical treatment needs of the court. The slicing of Arecae Semen in the Qing court required strict control of thickness, with an average thickness of 0.44 mm, which is significantly thinner than the Arecae Semen slices found in today's markets. The texture was softer, making them easier to chew and absorb. Both the Qing court Arecae Semen slices and the Muxiang Binglang Pills focused on the use of authentic medicinal materials, ensuring the quality of the medicine and enhancing the efficacy of Arecae Semen through meticulous selection and preparation.
China
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Drugs, Chinese Herbal/history*
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Humans
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Medicine, Chinese Traditional/history*
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History, 19th Century
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History, Ancient
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History, 17th Century
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History, 18th Century
6.Tracing origin of "Qinggong Maidong" production area based on analysis of literature and historical materials and identification of characteristics of Qinggong medicinal materials and cultural relics.
Ao-Yu REN ; Ting YAO ; Feng-Yuan LI ; Hua-Sheng PENG
China Journal of Chinese Materia Medica 2025;50(11):2931-2937
Maidong products are categorized into "Hang Maidong" and "Chuan Maidong". Since the Ming and Qing Dynasties, "Hang Maidong" has been regarded as having superior quality, but currently, it remains in name only in the market. This article reviewed historical materia medica and local chronicles from the Ming and Qing Dynasties and analyzed the historical evolution of Maidong production areas. The history of Maidong production in Zhejiang can be traced back to the Song Dynasty, and cultivation had already developed by at least the Ming Dynasty. During the Ming and Qing Dynasties, it was consistently used as a tribute. Ming Dynasty chronicles record "Chuan Maidong", which had already been cultivated on a large scale by the Qing Dynasty. "Hang Maidong" and "Chuan Maidong" share the same origin, with the former identifiable by the "gourd waist" shape of its tuberous root. Based on this, it can be inferred that the "Maimendong" herb illustrated in the Origins of Materia Medica(Ben Cao Yuan Shi) and the Maidong stored in the Qing Palace Imperial Pharmacy were both "Hang Maidong". The protection and development of the authentic "Hang Maidong" medicinal herb are urgently needed.
China
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Drugs, Chinese Herbal/history*
;
History, 17th Century
;
History, Ancient
;
Medicine, Chinese Traditional/history*
;
History, Medieval
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History, 16th Century
;
History, 18th Century
;
History, 15th Century
;
Plants, Medicinal/chemistry*
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History, 19th Century
;
History, 20th Century
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Humans
;
Materia Medica/history*
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History, 21st Century
7.Origin authentication of Bajitian based on herbal documents and local chronicles.
Jia-Feng CHEN ; Min-Zhen YIN ; Hua-Sheng PENG
China Journal of Chinese Materia Medica 2025;50(11):2945-2953
Bajitian is a commonly used Chinese medicinal material with a long history of medicinal use, and there is controversy over the authentication of its origins. This article combined historical herbal works with local chronicle records to authenticate the origins of Bajitian used in different regions, analyzed the local chronicle records, and illustrated the evolution of the origins of Bajitian in different regions. The results indicate that Illustrated Classic of Materia Medica first included Guizhou Bajitian and Chuzhou Bajitian. By integrating images and texts and local medicinal practices of Bajitian in the Guizhou and Chouzhou regions in ancient and modern times, it was inferred that the original plant of Guizhou Bajitian was likely to be Damnacanthus officinarum or D. giganteus, while the origin of Chuzhou Bajitian remained unclear. The medicinal history of Sichuan Bajitian was first recorded in the Supplementary Records of Famous Physicians during the Northern and Southern Dynasties. Based on the inference from herbal documents and local chronicle records, it was inferred that the original plant of Sichuan Bajitian may be Schisandra propinqua subsp. sinensis and so on. Guangdong Bajitian is an emerging variety in modern times, and it could date back to the Xingning County Annals in the 20th year during the Kangxi period of the Qing Dynasty(1681). The original plant of Guangdong Bajitian is Morinda officinalis, and Guangdong province became the true producing area of Bajitian in the late Qing Dynasty. This article clarified the origins of Bajitian in different regions by sorting out historical herbal documents and local chronicle records, providing a basis for the authentication of Bajitian in the field of herbology.
China
;
Drugs, Chinese Herbal/history*
;
History, Ancient
;
Medicine, Chinese Traditional/history*
;
Plants, Medicinal/chemistry*
;
History, Medieval
;
History, 20th Century
;
History, 19th Century
;
History, 18th Century
;
History, 17th Century
;
History, 16th Century
8.Cultivation history and cultivars of medicinal Paeonia lactiflora in China.
Zhen-Yu ZHANG ; Shan-Shan CHU ; Hua-Sheng PENG
China Journal of Chinese Materia Medica 2024;49(22):6241-6248
Paeoniae Radix Alba, a commonly used traditional Chinese medicine derived from the dried roots of Paeonia lactiflora, is mainly produced in Anhui, Zhejiang, Sichuan, Shandong, and Hunan provinces. Since this plant has been cultivated for a long period, various cultivars have been formed in different producing areas. Based on systematic herbal textual research and a review of local chronicles, this study investigated the germplasm resources of medicinal P. lactiflora in the five main producing areas of Paeoniae Radix Alba. Furthermore, it outlined the cultivation history and current status of the germplasm resources of medicinal P. lactiflora in these regions. The results indicated that among the 12 medicinal cultivars of P. lactiflora, 8 cultivars were monopetalous red flowers, which are consistent with the medicinal germplasm highly regarded throughout history in ancient medical books. Additionally, there are cultivars with monopetalous white flowers, polypetalous white flowers, and polypetalous pink flowers in the main producing areas, indicating the rich germplasm resources of medicinal P. lactiflora in China. This paper provides a survey basis for the germplasm conservation and rational resource utilization of high-quality medicinal P. lactiflora.
Paeonia/genetics*
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China
;
Plants, Medicinal/genetics*
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History, 20th Century
;
History, Ancient
;
History, 21st Century
;
History, 19th Century
;
Drugs, Chinese Herbal
;
Flowers/growth & development*
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History, 17th Century
;
History, 18th Century
9.Fern botanist Ren-Chang Ching and his taxonomic system.
Protein & Cell 2021;12(12):903-905
10.Preeminent Medical Missionary in the 20th Century: Oliver R. Avison
Yonsei Medical Journal 2018;59(1):1-3
No abstract available.
History, 19th Century
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History, 20th Century
;
Medical Missions, Official/history
;
Missionaries
;
Religious Missions/history

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