1.Evaluation of a newly developed oral and maxillofacial surgical robotic platform(KD-SR-01)in head and neck surgery:a preclinical trial in porcine models
Ma ZHONGKAI ; Guo ZHIYONG ; Ding ZHANGFAN ; Cao CHANG ; He JIALU ; Tang HEYI ; Hua YUFEI ; Hong JIAWEI ; Shen QIANG ; Grace Paka LUBAMBA ; Wang XIAOYI ; Yang ZHENG ; Zhu GUIQUAN ; Li CHUNJIE
International Journal of Oral Science 2024;16(4):759-766
Traditional open head and neck surgery often leaves permanent scars,significantly affecting appearance.The emergence of surgical robots has introduced a new era for minimally invasive surgery.However,the complex anatomy of the head and neck region,particularly the oral and maxillofacial areas,combined with the high costs associated with established systems such as the da Vinci,has limited the widespread adoption of surgical robots in this field.Recently,surgical robotic platform in China has developed rapidly,exemplified by the promise shown by the KangDuo Surgical Robot(KD-SR).Although the KD-SR has achieved some results comparable to the da Vinci surgical robot in urology and colorectal surgery,its performance in complex head and neck regions remains untested.This study evaluated the feasibility,effectiveness,and safety of the newly developed KD-SR-01,comparing it with standard endoscopic systems in head and neck procedures on porcine models.We performed parotidectomy,submandibular gland resection,and neck dissection,collected baseline characteristics,perioperative data,and specifically assessed cognitive workload using the NASA-TLX.None of the robotic procedures were converted to endoscopic or open surgery.The results showed no significant difference in operation time between the two groups(P=0.126),better intraoperative bleeding control(P=0.001),and a significant reduction in cognitive workload(P<0.001)in the robotic group.In conclusion,the KD-SR-01 is feasible,effective,and safe for head and neck surgery.Further investigation through well-designed clinical trials with long-term follow-up is necessary to establish the full potential of this emerging robotic platform.
2.Evaluation of a newly developed oral and maxillofacial surgical robotic platform(KD-SR-01)in head and neck surgery:a preclinical trial in porcine models
Ma ZHONGKAI ; Guo ZHIYONG ; Ding ZHANGFAN ; Cao CHANG ; He JIALU ; Tang HEYI ; Hua YUFEI ; Hong JIAWEI ; Shen QIANG ; Grace Paka LUBAMBA ; Wang XIAOYI ; Yang ZHENG ; Zhu GUIQUAN ; Li CHUNJIE
International Journal of Oral Science 2024;16(4):759-766
Traditional open head and neck surgery often leaves permanent scars,significantly affecting appearance.The emergence of surgical robots has introduced a new era for minimally invasive surgery.However,the complex anatomy of the head and neck region,particularly the oral and maxillofacial areas,combined with the high costs associated with established systems such as the da Vinci,has limited the widespread adoption of surgical robots in this field.Recently,surgical robotic platform in China has developed rapidly,exemplified by the promise shown by the KangDuo Surgical Robot(KD-SR).Although the KD-SR has achieved some results comparable to the da Vinci surgical robot in urology and colorectal surgery,its performance in complex head and neck regions remains untested.This study evaluated the feasibility,effectiveness,and safety of the newly developed KD-SR-01,comparing it with standard endoscopic systems in head and neck procedures on porcine models.We performed parotidectomy,submandibular gland resection,and neck dissection,collected baseline characteristics,perioperative data,and specifically assessed cognitive workload using the NASA-TLX.None of the robotic procedures were converted to endoscopic or open surgery.The results showed no significant difference in operation time between the two groups(P=0.126),better intraoperative bleeding control(P=0.001),and a significant reduction in cognitive workload(P<0.001)in the robotic group.In conclusion,the KD-SR-01 is feasible,effective,and safe for head and neck surgery.Further investigation through well-designed clinical trials with long-term follow-up is necessary to establish the full potential of this emerging robotic platform.
3.Effect and prognosis of tumor-type artificial knee prosthesis replacement for treatment of malignant bone tumors around the knee
Heyi SHEN ; Lizhi LI ; Zhuangzhuang WU ; Zhi LYU
Cancer Research and Clinic 2020;32(10):718-723
Objective:To investigate the effects, complications and survival of patients tumor-type artificial knee prosthesis replacement for treatment of malignant bone tumors around the knee.Methods:The data of 47 patients undergoing tumor-type knee prosthesis replacement in Shanxi Medical University from January 2010 to April 2018 was retrospectively analyzed. There were 21 males and 26 females, with a median age of 21 years (7-70 years). There were 39 cases of osteosarcomas, 3 cases of chondrosarcomas, 2 cases of malignant fibrous histiocytomas, 2 cases of giant cell bone tumors, and 1 case of fibrosarcoma. The involved locations were the distal femur in 35 cases and proximal tibia in 12 cases. Patients with osteosarcoma and malignant fibrous histiocytomas received chemotherapy for 2 courses before operation and 4-6 courses after operation. The data included the survival time, prosthesis survival time, complications, limb function, tumor recurrence and lung metastasis of patients.Results:Patients were followed up for a median time of 25 months (5-102 months). The 1-year, 3-year and 5-year overall survival rates were 95.74%, 71.29% and 58.06%, respectively. The 1-year, 3-year and 5-year disease-free survival rates were 86.42%, 55.49% and 50.86%, respectively. Local tumor recurrence occurred in 10 patients (21.28%) within 3 years after operation. Of the 10 patients, 8 cases had a recurrence of the soft tissue tumor and then they received the resection surgery; the other 2 patients underwent amputation of the diseased limb. The pulmonary metastasis occurred in 15 patients (31.91%). The 5-year survival rate of prosthesis was 82.33%, and the 5-year survival rate of prosthesis in patients with tumor in the distal femur was higher than that in patients with tumor in the proximal tibia [86.96% vs. 75.00%, P = 0.338]. The periprosthetic infection occurred in 3 patients (6.38%), and 1 case (2.13%) received revision after prosthesis loosening, 1 case (2.13%) received revision after prosthesis breakage. At the patient's last follow-up, the Musculoskeletal Tumor Society (MSTS) score was 21 points (15 points, 24 points), and the excellent rate was 61.70% (29/47). The incidence of extensor lag in patients with tumor in the proximal tibia was higher than that in patients with tumor in the distal femur, and the difference was statistically significant [33.33% (4/12) vs. 2.86% (1/35), P = 0.016]. Conclusions:Tumor-type artificial knee prosthesis replacement can effectively treat malignant bone tumors around the knee and maintain satisfactory limb function and patients' survival rate. However, the postoperative complications may lead to limb salvage failure. It is necessary to reduce the occurrence of complications through standardized chemoradiotherapy, extensive and strict tumor resection and proper rehabilitation exercises.

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