Humans ; Herpesvirus 3, Human ; Myelitis, Transverse/complications* ; Guillain-Barre Syndrome/complications* ; Herpes Zoster/complications* ; Varicella Zoster Virus Infection/complications*

OBJECTIVETo evaluate the clinical efficacy of intradermal injection of methylene blue for treatment of moderate to severe acute thoracic herpes zoster and prevention of postherpetica neuralgia in elderly patients.

METHODSSixty-four elderly patients with herpes zoster were randomized to receive a 10-day course of intradermal injection of methylene blue and lidocaine plus oral valaciclovir (group A, 32 cases) and intradermal injection of lidocaine plus oral valaciclovir (group B).Herpes evaluation index, pain rating index, incidence of postherpetic neuralgia, and comprehensive therapeutic effect were compared between the two groups at 11, 30 and 60 days after the treatment.

RESULTSThe baseline characteristics were comparable between the two groups (all P>0.05). Compared with that in group B, the time for no new blister formation, blister incrustation and decrustation, and pain relief was significantly shortened in group A (P<0.05) with also obviously lower pain intensity after the treatment. The incidence of postherpetic neuralgia was significantly lower in group A than in group B at 30 days (P<0.05), but not at 60 and 90 days after the treatment. The total clinical response rate was 93.8% in group A, much higher than that in group B (62.5%, P<0.05).

CONCLUSIONIntradermal injection of methylene blue can effectively shorten the disease course, reduce the pain intensity and prevent the development of postherpetic neuralgia in elderly patients with herpes zoster.

Acyclovir ; administration & dosage ; analogs & derivatives ; therapeutic use ; Aged ; Herpes Zoster ; complications ; Humans ; Incidence ; Injections, Intradermal ; Lidocaine ; administration & dosage ; therapeutic use ; Methylene Blue ; administration & dosage ; therapeutic use ; Neuralgia, Postherpetic ; therapy ; Pain Measurement ; Valine ; administration & dosage ; analogs & derivatives ; therapeutic use

Acyclovir ; therapeutic use ; Anti-Inflammatory Agents ; therapeutic use ; Antiviral Agents ; therapeutic use ; Brain Stem ; pathology ; virology ; Encephalitis ; complications ; diagnosis ; drug therapy ; virology ; Herpes Zoster ; complications ; diagnosis ; drug therapy ; virology ; Herpes Zoster Oticus ; diagnosis ; drug therapy ; etiology ; virology ; Humans ; Male ; Methylprednisolone ; therapeutic use ; Middle Aged

Acupuncture Therapy ; Aged ; Dysuria ; etiology ; physiopathology ; therapy ; Herpes Zoster ; complications ; virology ; Herpesvirus 3, Human ; physiology ; Humans ; Male ; Perineum ; virology

Acupuncture Therapy ; Herpes Zoster ; complications ; Humans ; Male ; Middle Aged ; Motor Neuron Disease ; etiology ; therapy ; Neuralgia, Postherpetic ; etiology ; therapy

The clinical data of 3 cases of Ramsay-Hunt syndrome concurrent with ipsilateral vocal cord paralysis were retrospectively analyzed, and the relevant literatures were also reviewed. Ramsay-Hunt syndrome is a kind of disease characterized by heavy ear pain, herpes zoster oticus and inner ear neurologic symptoms, which can also affect the vocal cords and give rise to vocal cords paralysis. Ramsay-Hunt syndrome can cause multiple in flammation of cranial nerves. The viral infection can also involve the 3rd and 10th cranial nerves. It mainly damage the facial nerve, followed by the involvement of vestibulocochlear nerve. The vagus nerve damage is rare, so the relevant clinical reports are less. It is important to take the objective data as well as subjective symptoms of the patients into consideration to make a definite diagnosis, so that we can treat it as soon as possible to achieve better curative effect.
Adult ; Aged ; Female ; Herpes Zoster Oticus ; complications ; Humans ; Male ; Middle Aged ; Vocal Cord Paralysis ; complications

AIDS is a serious threat to human health and has become a global public health problem. Highly active antiretroviral therapy (HAART) can effectively reduce AIDS mortality rate, but has limitations in improving the patient's symptoms and improve quality of life. The literatures about the therapeutic effect of acupuncture and moxibustion on HIV/AIDS were reviewed. The symptoms of HIV/AIDS and the procedures of treatments were analyzed. The acupuncture intervention on HIV/AIDS was investigated. It showed that the acupuncture intervention may markedly improve the condition of HIV/AIDS. From a clinical point of view, we discussed the acupuncture treatment of AIDS-related symptoms, effectiveness and safety evaluation. It may contribute to build a comprehensive treatment system in which acupuncture is dominated for HIV/AIDS.
Acquired Immunodeficiency Syndrome ; complications ; Acupuncture Therapy ; methods ; Cough ; complications ; therapy ; Diarrhea ; complications ; therapy ; Herpes Zoster ; complications ; therapy ; Humans

OBJECTIVEAnalysis of professor Li Fa-zhi in the treatment of AIDS drug laws of herpes zoster and postherpetic neuralgia, provide reference for the use of Chinese medicine treatment of AIDS, herpes zoster and postherpetic neuralgia.

METHODBy using the method of analyzing the complex network of Weishi county, Henan in 2007 October to 2011 July during an interview with professor Li Fa-zhi treatment of AIDS of herpes zoster and postherpetic neuralgia patients, patients are input structured clinical information collection system, into the analysis of the data, carries on the research analysis theory of traditional Chinese medicine compatibility system algorithm and complex network analysis the use of complex networks.

RESULTThe use of multi-dimensional query analysis of AIDS drugs, the core of herpes zoster and postherpetic neuralgia treated in this study are Scutellariae Radix, Glucyrrhizae Radix, Carthame Flos, Plantaginis Semen, Trichosamthis Fructus, Angelicae Sinensis Radix, Gentianae Radix; core prescription for Longdan Xiegan decoction and Trichosanthes red liquorice decoction.

CONCLUSIONProfessor Li Fa-zhi treatment of AIDS, herpes zoster and postherpetic neuralgia by clearing heat and removing dampness and activating blood circulation to.

Acquired Immunodeficiency Syndrome ; complications ; Data Mining ; Herpes Zoster ; complications ; drug therapy ; Humans ; Medical Informatics ; methods ; Medical Records ; Medicine, Chinese Traditional ; methods

Aged ; Aged, 80 and over ; Bloodletting ; Female ; Herpes Zoster ; complications ; Humans ; Middle Aged ; Neuralgia, Postherpetic ; etiology ; therapy

A 55-year-old woman presented with diplopia following painful skin eruptions on the right upper extremity. On presentation, she was found to have 35 prism diopters of esotropia and an abduction limitation in the left eye. Two weeks later, she developed blepharoptosis and anisocoria with a smaller pupil in the right eye, which increased in the darkness. Cerebrospinal fluid analysis showed pleocytosis and a positive result for immunoglobulin G antibody to varicella zoster virus. She was diagnosed to have zoster meningitis with Horner's syndrome and contralateral abducens nerve palsy. After intravenous antiviral and steroid treatments, the vesicular eruptions and abducens nerve palsy improved. Horner's syndrome and diplopia resolved after six months. Here we present the first report of Horner's syndrome and contralateral abducens nerve palsy associated with zoster meningitis.
Abducens Nerve Diseases/diagnosis/*etiology ; Antibodies, Viral/*analysis ; Diagnosis, Differential ; Electromyography ; Female ; Follow-Up Studies ; Herpes Zoster/*complications/diagnosis/virology ; Herpesvirus 3, Human/*immunology ; Horner Syndrome/diagnosis/*etiology ; Humans ; Magnetic Resonance Imaging ; Meningitis/*complications/diagnosis/virology ; Middle Aged ; Tomography, X-Ray Computed