Objective To explore the application of PDCA cycle management mode in public health emergencies in gen-eral hospitals.Methods The PDCA cycle management model was carried out.35 medical workers from Shawan People's Hos-pital of Panyu District,Guangzhou from January 2021 to December 2022 were included as research objects and divided according to different time points as cut-off points.The PDCA cycle management model was not implemented from January to December 2021.The PDCA cycle mode management will be implemented from January to December 2022.The treatment time,job burnout and emergency response ability of medical staff before and after PDCA cycle management were compared.Results After the im-plementation of PDCA cycle mode management,the pre-hospital examination,hospital admission,symptom examination and dis-ease diagnosis of medical staff were less than those before the implementation of PDCA cycle mode management,and the differ-ence was significant(P＜0.05).After the implementation of PDCA cycle mode management,the scores of emotional consump-tion and deindividuation tendency of medical staff were lower than those before the implementation of PDCA cycle mode manage-ment,while the scores of low sense of accomplishment after the implementation of PDCA cycle mode management were higher than those before the implementation of PDCA cycle mode management,with significant differences(P＜0.05).After the imple-mentation of PDCA cycle mode management,the emergency ability scores of medical staff were higher than those before the imple-mentation of PDCA cycle mode management,and the difference was significant(P＜0.05).Conclusion PDCA cycle manage-ment mode has a good application effect in public health emergencies in general hospitals,which is conducive to more efficient and successful treatment of public health emergencies.