1.COVID-19 vaccine acceptance among kidney transplant recipients in Singapore.
Ian Tatt LIEW ; Hanis Abdul KADIR ; Sobhana THANGARAJU ; Quan Yao HO ; Eleanor NG ; Fiona FOO ; Terence KEE
Singapore medical journal 2025;66(2):73-80
INTRODUCTION:
A successful vaccination programme forms the cornerstone of controlling coronavirus disease 2019 (COVID-19). The unprecedented speed of COVID-19 vaccine development and lack of long-term data have raised fears regarding its safety and efficacy. Vaccine hesitancy can undermine the uptake, and hence success of the vaccination programme. Given the high complication rates of COVID-19 infections in kidney transplant recipients, it is particularly important to identify and address vaccine hesitancy in this population.
METHODS:
We conducted a cross-sectional survey among kidney transplant recipients attending transplant clinic between 5 April and 5 May 2021. The survey assessed attitudes towards COVID-19, willingness/hesitancy towards COVID-19 vaccination, vaccination concerns and prompts to vaccination. This was scored on a Likert scale with scores ranging from 'strongly disagree' - 1 point to 'strongly agree' - 5 points.
RESULTS:
One hundred and one completed responses were captured. Of these, 86% respondents reported to agree or strongly agree to vaccination. This was despite significant concerns of allograft rejection (mean score 4.12, standard deviation [SD] 0.97) and decreased immunosuppressant efficacy (mean score 4.14, SD 0.96) with vaccination. Multivariable model showed a positive association with transplant vintage of ≥ 5 years (median 2.41), lower educational levels of secondary school or less (median 5.82) and healthcare provider advocacy (median 1.88) in predicting vaccine acceptance.
CONCLUSIONS
Vaccine acceptance rate was high among kidney transplant recipients. Vaccine hesitancy remains a concern in those with a transplant vintage of less than 5 years and those with tertiary educational level. Healthcare provider advocacy is important in improving vaccine acceptance rates.
Humans
;
Kidney Transplantation
;
Singapore/epidemiology*
;
Male
;
Cross-Sectional Studies
;
Female
;
COVID-19 Vaccines
;
COVID-19/epidemiology*
;
Middle Aged
;
Adult
;
Transplant Recipients/psychology*
;
Patient Acceptance of Health Care/statistics & numerical data*
;
Vaccination Hesitancy/psychology*
;
Surveys and Questionnaires
;
Vaccination/psychology*
;
Aged
;
SARS-CoV-2
2.Prevalence of complexity in primary care and its associated factors: A Singapore experience.
Jing Sheng QUEK ; Jeremy Kaiwei LEW ; Eng Sing LEE ; Helen Elizabeth SMITH ; Sabrina Kay Wye WONG
Annals of the Academy of Medicine, Singapore 2025;54(2):87-100
INTRODUCTION:
As the population ages, patient complexity is increasing, intensifying the demand for well-resourced, coordinated care. A deeper understanding of the factors contributing to this complexity is essential for optimising resource allocation. This study evaluates the prevalence of complex care needs in Singapore's primary care settings and identifies the factors associated with these needs.
METHOD:
Using a qualitative study design, we developed a patient complexity questionnaire to assess how Singapore family physicians recognise patient complexity. Sixty-nine experienced primary care physicians applied this tool to assess patient encounters, categorising each as "routine care" (RC), "medically challenging" (MC), or "complex care" (CC). We compared the care needs across these categories and used mixed-effects multinomial logistic regression to determine the independent predictors of complexity.
RESULTS:
Of the 4327 encounters evaluated, 15.0% were classified as CC, 18.5% as MC, and 66.4% as RC. In both CC and MC encounters, the most common medical challenges were polypharmacy (66.2% in CC, 44.9% in MC); poorly controlled chronic conditions (41.3% in CC, 24.5% in MC); and treatment interactions (34.4% in CC, 26.0% in MC). Non-medical issues frequently identified included low health literacy (32.6% in CC, 20.8% in MC); limited motivation for healthy lifestyle behaviours (27.2% in CC, 16.6% in MC); and the need for coordinated care with hospital specialists (24.7% in CC, 17.1% in MC). The top 3 independent predictors of complexity included mobility limitations requiring assistance (odds ratio [OR] for requiring wheelchair/trolley: 7.14 for CC vs RC, 95% confidence interval [CI] 4.74-10.74); longer consultation times with physicians (OR for taking >20 minutes for doctor's consultation: 3.96 for CC vs RC, 95% CI 2.86-5.48); and low socioeconomic status (OR for living in 1- or 2-room HDB flats: 2.98 for CC vs RC, 95% CI 1.74-5.13).
CONCLUSION
High care needs, encompassing both CC and MC encounters, were prevalent in primary care interactions. These findings highlight that relying solely on chronic disease count is insufficient to capture the full spectrum of patient complexity.
Singapore/epidemiology*
;
Humans
;
Primary Health Care/statistics & numerical data*
;
Male
;
Female
;
Middle Aged
;
Aged
;
Adult
;
Surveys and Questionnaires
;
Prevalence
;
Polypharmacy
;
Qualitative Research
;
Chronic Disease/therapy*
;
Logistic Models
3.Validation and cultural adaptation of the Japanese version of the Self-Care Inventory across different research settings: a cross-sectional study.
Atsushi TAKAYAMA ; Shiho KOIZUMI ; Yoshihito KATO ; Tatsuya ISOMURA ; Tatsuyuki HOSOYA ; Koji KAWAKAMI
Environmental Health and Preventive Medicine 2025;30():85-85
BACKGROUND:
Self-care is increasingly recognized as the foundation of person-centered healthcare and a key driver for simultaneously improving population health outcomes and reducing healthcare expenditures. While the Self-Care Inventory (SCI) has been validated in several languages, Japan lacks a standardized instrument for assessing self-care in the general adult population. Moreover, it remains unclear whether the SCI reflects culturally specific self-care behaviors and retains its psychological measurement properties in non-Western contexts. Addressing both aspects, this study aimed to evaluate the Japanese version of the SCI (JSCI) in terms of its psychometric properties and its association with concrete health behaviors.
METHODS:
We adapted the JSCI following COSMIN guidelines using forward/backward translation, expert review, and cognitive debriefing. Psychometric evaluation was based on two samples: a nationwide web-based survey (n = 504) and a community-based paper survey (n = 75). Structural validity was examined via CFA; internal consistency via Cronbach's alpha and McDonald's omega; and test-retest reliability via ICCs. Convergent and criterion validity were assessed through correlations with relevant psychological constructs. Measurement invariance and DIF across modes were tested, and associations with five external self-care behaviors were evaluated using AUC.
RESULTS:
The hypothesized three-factor structure of the JSCI was supported across both administration modes (CFI = 0.926-0.942; SRMR < 0.06), although some subscales had elevated RMSEA. Internal consistency was acceptable to high (α = 0.75-0.85; ω = 0.81-0.92). ICCs indicated moderate to good temporal stability. JSCI scores correlated with self-care efficacy and other related constructs, supporting convergent and criterion validity. Configural invariance was confirmed, and no significant DIF was detected across modes. JSCI scores modestly discriminated individuals engaging in concrete self-care behaviors such as physical activity, strength training, Helicobacter pylori testing, and having a regular primary or dental care provider (AUCs = 0.62-0.80).
CONCLUSIONS
The JSCI demonstrated satisfactory psychometric properties and structural validity across diverse research settings. Its observed associations with a range of meaningful self-care behaviors support the scale's ecological and practical relevance in the Japanese context. The JSCI may serve as a reliable tool for evaluating and promoting self-care in both research and population health initiatives.
Humans
;
Japan
;
Self Care/statistics & numerical data*
;
Psychometrics
;
Male
;
Female
;
Adult
;
Cross-Sectional Studies
;
Middle Aged
;
Reproducibility of Results
;
Surveys and Questionnaires
;
Young Adult
;
Aged
;
Health Behavior
;
Translations
;
East Asian People
4.Attitudes of visitors at adult intensive care unit toward organ donation and organ support.
Nga-Wing TSAI ; Yee-Man LEUNG ; Pauline Yeung NG ; Ting LIONG ; Sui-Fong LEE ; Chun-Wai NGAI ; Wai-Ching SIN ; Jenny KOO ; Wai-Ming CHAN
Chinese Medical Journal 2019;132(3):373-376
Adolescent
;
Adult
;
Cross-Sectional Studies
;
Female
;
Health Knowledge, Attitudes, Practice
;
Humans
;
Intensive Care Units
;
statistics & numerical data
;
Male
;
Middle Aged
;
Organ Transplantation
;
psychology
;
statistics & numerical data
;
Surveys and Questionnaires
;
Tissue and Organ Procurement
;
statistics & numerical data
;
Young Adult
5.Health Care-seeking Behaviors in Mosuo and Pumi People in Yunnan Ninglang.
Hai Yin ZHANG ; Hua ZHONG ; Yuan Yuan LIN ; Xian Wei ZENG ; Li XU ; Guo Hua FENG ; Yu Jun WEI ; Jian Zhong YANG
Acta Academiae Medicinae Sinicae 2019;41(3):331-337
Objective To investigate the health care-seeking behaviors of Mosuo and Pumi people.Methods The subjects were enrolled by using the multi-stage stratified random sampling method and surveyed by the self-designed questionnaire.Results To tally 1669 subjects including 1121 Mosuo people and 548 Pumi people completed the survey.When Mosuo and Pumi people suffer from ailments,they preferred to buy drugs in drugstores(47.3% for Mosuo and 46.9% for Pumi),followed by visiting a local township hospital(27.0% for Mosuo and 24.3% for Pumi).When they suffered from severe diseases,they preferred to visit the county/city/state hospital(93.4% for Mosuo and 91.1% for Pumi).The mental disease were mainly treated in the county/city/state hospitals(49.3% for Mosuo and 52.7% for Pumi);notably,39.3% of the Mosuo respondents and 31.5% of the Pumi respondents skipped this question.Conclusion Health education,including awareness-raising activities on mental health,should be enhanced in Mosuo and Pumi people to further improve their health care-seeking behaviors.
China
;
Humans
;
Patient Acceptance of Health Care
;
statistics & numerical data
;
Surveys and Questionnaires
6.An investigation on the need, the utilization, and the influencing factors of dental services for pre-school children in selected areas in Chongqing province.
Jing-Xue WANG ; Zheng-Yan YANG ; Xiao-Yan WU ; Ting CAI ; Li DENG ; Xiao-Yan LÜ ; Xian-Bin DING ; Zhi ZHOU
West China Journal of Stomatology 2019;37(2):187-192
OBJECTIVE:
The aim of this study is to survey the need, the utilization, and the influencing factors of dental services for children in selected areas in Chongqing province by investigating their oral health status. The survey will provide references for preventive oral health care in targeted Chongqing areas, which may improve the level of oral health among pre-school children.
METHODS:
Random cluster sampling was utilized according to standards of the Fourth National Oral Health Epidemiological sampling survey, and 1 300 children between the ages of three and four years old from 24 kindergartens in 12 subdistricts of three areas in Chongqing were interviewed for free dental checkups and to participate in the survey. The questionnaires were designed according to the Anderson model and were answered by the children's parents. The results were analyzed utilizing Chi-square test logistic regression.
RESULTS:
The prevalence rate of caries among the pre-school children in selected areas of Chongqing was 55.4%, the decay, missing, filled surface (dmfs) was 6 696, the mean dmfs was 5.2, and the caries filling constituent ratio was 2.3%. A total of 1 173 questionnaires were analyzed. The ratio for seeing a dentist for therapeutic reasons was 6.31% (74/1 173) and for prevalence was 22.93% (269/1 173).
CONCLUSIONS
The oral health service needs of pre-school children in selected areas of Chongqing are large and the oral health service utilization rate is low. Oral health care processes are arduous; thus, targeted oral prevention policies should be created.
Child
;
Child, Preschool
;
Dental Care
;
statistics & numerical data
;
Dental Caries
;
Dental Health Surveys
;
Humans
;
Oral Health
;
Prevalence
7.Health Behavior, Health Service Use, and Health Related Quality of Life of Adult Women in One-person and Multi-person Households
Korean Journal of Women Health Nursing 2019;25(3):299-314
PURPOSE: This study was to identify health behavior, health service use, and health related quality of life of adult women in one-person and multi-person households. METHODS: It was used data from the 7th Korea National Health and Nutrition Examination Survey (KNHANES VII-2017). Subjects were 2,522 women with age of 19 to 64 years in 2017. Complex sampling design and data analysis were performed using SPSS 20.1. RESULTS: Women in one-person households had higher rates of alcohol drinking (χ²=13.77, p=.003), smoking (χ²=16.07, p=.001), unmet medical care (χ²=8.77, p=.004) and non-practice of cancer screening (χ²=13.77, p=.003) compared to women in multi-person households. Health-related quality of life was also lower for women in one-person households (t=−2.46, p=.015). Factors affecting health-related quality of life in one-person households were household income, job status, and unmet dental care, having 32.4% explanatory power. One-person household women with low incomes, no jobs, and unmet dental care showed low health-related quality of life. In comparison, factors affecting health-related quality of life of women in multi-person household women were age, education level, unmet medical care, and unmet dental care, having 10.4% explaining power. Women in multi-person households with age of 60–64, low education level, unmet medical care, and unmet dental care showed low health-related quality of life. CONCLUSION: Health promotion strategies should be developed based on unique understanding of social, economic, and health of adult women in one-person and multi-person households.
Adult
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Alcohol Drinking
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Dental Care
;
Early Detection of Cancer
;
Education
;
Family Characteristics
;
Female
;
Health Behavior
;
Health Promotion
;
Health Services
;
Humans
;
Korea
;
Nutrition Surveys
;
Quality of Life
;
Smoke
;
Smoking
;
Statistics as Topic
8.Factors Influencing Health-related Quality of Life among Older Korean Women with Osteoporosis: Using Data from Korea National Health and Nutrition Examination Survey 2015 to 2016.
Eunyoung PARK ; Hyung Ran PARK
Korean Journal of Rehabilitation Nursing 2018;21(2):140-150
PURPOSE: The purpose of this study was to investigate osteoporosis prevalence and factors influencing health-related quality of life (HRQoL) among older Korean women with osteoporosis. METHODS: The study design was a retrospective study using secondary data analysis. Data for 1,355 women aged 65 and older from the Korea National Health and Nutrition Examination Survey (KNHANES) 2015 to 2016 were included. Linear regression analysis was conducted for influential factors on HRQoL, measured by the Euro Quality of Life-5D (EQ-5D). RESULTS: The prevalence of osteoporosis was 41.3% in older Korean women. The EQ-5D index score was lower in older women with osteoporosis (0.83) than those without osteoporosis (0.86). Lower HRQoL in older Korean women with osteoporosis was associated with lower household income, perceived health status as bad, comorbidity, activity restriction, and stress. CONCLUSION: The findings indicate that the prevalence of osteoporosis was high in older Korean women. In addition, healthcare professionals need to consider individual conditions such as economic status, perceived health status, other chronic diseases, activity restriction and level of stress for improvement of HRQoL in older Korean women with osteoporosis.
Chronic Disease
;
Comorbidity
;
Delivery of Health Care
;
Family Characteristics
;
Female
;
Humans
;
Korea*
;
Linear Models
;
Nutrition Surveys*
;
Osteoporosis*
;
Prevalence
;
Quality of Life*
;
Retrospective Studies
;
Statistics as Topic
9.Economic burden of hepatitis C patients and related influencing factors in Guangdong province.
Q M WU ; Y LI ; X B FU ; F YANG ; J LI ; H Z HUANG ; J YAN ; P LIN
Chinese Journal of Epidemiology 2018;39(7):931-936
Objective: To investigate the economic burden of hepatitis C patients and related factors in Guangdong province. Methods: In this study, cluster sampling method was used to select cases, including acute hepatitis C, chronic hepatitis C and liver cirrhosis cases from eligible outpatients and inpatients in 1 or 2 large general hospitals in all the 21 cities in Guangdong province. Questionnaire survey was conducted for all the hepatitis C patients to analyze their economic burden, while multivariate linear regression model was used to identify the related influencing factors. Results: A total of 356 hepatitis C patients were enrolled in the study, with 176 outpatients (49.4%) and 180 inpatients (50.6%) respectively. The average age of the study subjects was (44.79±11.73) year-olds. The annual direct economic costs of patients with acute hepatitis C, chronic hepatitis C and liver cirrhosis were 10 703.22 (IQR: 7 396.75-16 891.91), 14 886.63 (IQR: 7 274.00-30 228.25) and 28 874.00 (IQR: 13 093.69-56 350.00) Yuan (RMB) respectively. The annual indirect costs appeared as 2 426.99 (IQR: 1 912.18-7 354.52), 3 235.99 (IQR: 1 323.81-6 619.07) and 5 442.35 (IQR: 3 235.99-10 296.33) Yuan (RMB) respectively. The annual intangible costs were 5 000.00 (IQR:2 000.00-10 000.00), 10 000.00 (IQR: 4 000.00-30 000.00) and 10 000.00 (IQR: 3 000.00-100 000.00) Yuan (RMB) respectively. The annual total costs were 22 306.17 (IQR: 14 581.24-50 569.17), 38 050.33 (IQR: 17 449.57-68 319.62) and 80 152.18 (IQR: 40 856.09-228 460.79) Yuan (RMB) respectively. Results from the multiple linear regression analysis showed that factors as: annual hospitalization days, annual number of outpatient visits, annual number of hospitalization, type of disease and the levels of the hospitals were related to the economic burden of patients with hepatitis C. Conclusion: Patients with HCV-related diseases presented serious economic problem which calls for close attention in Guangdong province.
Adult
;
China/epidemiology*
;
Cities
;
Cost of Illness
;
Female
;
Health Care Costs/statistics & numerical data*
;
Hepatitis B/epidemiology*
;
Hepatitis C/economics*
;
Hospitalization
;
Humans
;
Liver Cirrhosis/epidemiology*
;
Male
;
Surveys and Questionnaires
10.Epidemiological characteristics of hepatitis A and hepatitis E in different periods of vaccination in China, 2004-2015.
X J SUN ; F Z WANG ; H ZHENG ; N MIAO ; H Q WANG ; Z D YIN ; G M ZHANG
Chinese Journal of Epidemiology 2018;39(10):1351-1355
Objective: Through analyzing the epidemiological characteristics of hepatitis A and E and the situation of vaccination, to promote the recommendation profile on Hepatitis E vaccination program, in China. Methods: Three phases of time span were divided as 2004-2007, 2008-2011 and 2012-2015, with age groups divided as <20, 20-29, 30-39 and ≥40. Incidence rates in both different phases and age groups were compared. Numbers of Hepatitis A and E vaccines released and used, were described. Results: Between 2004 and 2015, a declining trend in the reported incidence of hepatitis A (t=-12.15, P<0.001), but an increasing trend in hepatitis E (t=6.63, P<0.001) were noticed. The mean number of hepatitis A cases declined from 6 515 to 1 986 between 2004 and 2007 while the number of hepatitis E cases increased from 1 491 to 2 277 between 2012 and 2015. The peaks of hepatitis E appeared persistent annually, in March. The incidence of hepatitis A declined in three regions, with the western region (3.46/100 000) much higher than the eastern (1.13/100 000) or central regions (1.14/100 000) (χ(2)=32 630, P<0.01). The incidence of hepatitis E increased both in the central (1.74/100 000) and western regions (1.58/100 000), but more in the eastern region (2.66/100 000) (χ(2)=6 009, P<0.01). Incidence of hepatitis A declined in all age groups and declined by 84.36% among the 0-19 group. However, the incidence of hepatitis E showed an increasing trend among the ≥20 group. Incidence rates appeared higher in the older age groups. The coverage of hepatitis A vaccine increased from 62.05% to 93.54%, but with a negative association seen between the coverage of Hepatitis A vaccine and the incidence (F=10.69, χ(2)<0.05). Conclusion: The incidence of Hepatitis A declined sharply in China while hepatitis E was still increasing from 2004 to 2015, calling for the expansion on the coverage of Hepatitis E vaccine in the whole population.
Adolescent
;
Adult
;
Aged
;
China/epidemiology*
;
Health Care Surveys
;
Hepatitis A/epidemiology*
;
Hepatitis A Vaccines/administration & dosage*
;
Hepatitis E/epidemiology*
;
Humans
;
Immunization/statistics & numerical data*
;
Immunization Programs
;
Incidence
;
Middle Aged
;
Population Surveillance
;
Vaccination/statistics & numerical data*
;
Young Adult

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