1.Suspected Neurotoxic Envenomation in a 5- year-old Child: A Syndromic Approach
Brunei International Medical Journal 2026;22():15-18
Snakebite envenomation remains a significant cause of morbidity and mortality in Southeast Asia. Accurate identification of the snake species or even confirming biting incident can be challenging, especially in children. This case report discussed the essential considerations for a suspected snakebite in a paediatric patient who presented to the emergency department with progressive neurological signs consistent with envenomation, necessitating empiric antivenom administration and mechanical ventilation. It highlights the diagnostic and therapeutic challenges encountered, emphasising the critical need for prompt identification of envenomation, judicious use of empirical antivenom therapy, and comprehensive supportive critical care. Urgent and effective interventions, including ventilatory support have been demonstrated to enhance outcomes in severe neurotoxic envenomation cases
2.Acquired Methaemoglobinaemia Following Inhalation of Alkyl Nitrites (“Super Rush”)
Brunei International Medical Journal 2026;22():31-34
Case Report Open Access 15 Methaemoglobinaemia is a rare but potentially life -threatening cause of hypoxemia that may be overlooked in emergency settings. We report a case of acquired methaemoglobinaemia in a 36 - year-old man following inhalation of an alkyl nitrite –containing recreational product (“Super Rush ”). The patient presented with cyanosis and hypoxemia on pulse oximetry despite minimal symptoms and preserved arterial oxygen tension. Diagnosis was confirmed by co -oximetry demonstrating elevated methaemoglobin levels. Prompt treatment with intravenous methylene blue led to rapid clinical and biochemical improvement. This case highlights the importance of suspecting and recognising recreational inhalants as a cause of methaemoglobinaemia and the utility of co -oximetry in patients with unexplained cyanosis and a saturation gap
3.Suspected Neurotoxic Envenomation in a 5- year-old Child: A Syndromic Approach
Brunei International Medical Journal 2026;22():15-18
Snakebite envenomation remains a significant cause of morbidity and mortality in Southeast Asia. Accurate identification of the snake species or even confirming biting incident can be challenging, especially in children. This case report discussed the essential considerations for a suspected snakebite in a paediatric patient who presented to the emergency department with progressive neurological signs consistent with envenomation, necessitating empiric antivenom administration and mechanical ventilation. It highlights the diagnostic and therapeutic challenges encountered, emphasising the critical need for prompt identification of envenomation, judicious use of empirical antivenom therapy, and comprehensive supportive critical care. Urgent and effective interventions, including ventilatory support have been demonstrated to enhance outcomes in severe neurotoxic envenomation cases
4.Acquired Methaemoglobinaemia Following Inhalation of Alkyl Nitrites (“Super Rush”)
Brunei International Medical Journal 2026;22():31-34
Case Report Open Access 15 Methaemoglobinaemia is a rare but potentially life -threatening cause of hypoxemia that may be overlooked in emergency settings. We report a case of acquired methaemoglobinaemia in a 36 - year-old man following inhalation of an alkyl nitrite –containing recreational product (“Super Rush ”). The patient presented with cyanosis and hypoxemia on pulse oximetry despite minimal symptoms and preserved arterial oxygen tension. Diagnosis was confirmed by co -oximetry demonstrating elevated methaemoglobin levels. Prompt treatment with intravenous methylene blue led to rapid clinical and biochemical improvement. This case highlights the importance of suspecting and recognising recreational inhalants as a cause of methaemoglobinaemia and the utility of co -oximetry in patients with unexplained cyanosis and a saturation gap
5.Evaluation of Dental Students’ Medical History Records on Hypertension and Diabetes Mellitus at The National University of Malaysia
Jun Ai Chong ; Fara Azwin Adam ; Ang Yee ; Laila Azwa Hassan ; Hetal Ashvin Kumar Mavani ; Rama Krsna Rajandram
Malaysian Journal of Medicine and Health Sciences 2023;19(No.4):201-206
Introduction: A thorough medical history ensures safe dental practice. A good medical history guides clinicians in
risk stratification to avoid medical emergencies and improve preparedness to prevent patient morbidity and mortality. This clinical audit aims to analyse the medical history taken by the dental students in patients with hypertension
and/or diabetes mellitus (DM) and subsequently, recommend improvements in history-taking components in the
dental practice. Methods: Hundred and two patients’ folders from the Faculty of Dentistry were examined by two
independent auditors using a validated history-taking evaluation form. Six components of the medical history were
classified as good or bad practices. Sociodemographic factors and distribution of the American Society of Anesthesiologists (ASA status) were described. The level of completeness of medical history records with years of study was
assessed using the Chi-square test. Results: None of the students met 100% of the components required in medical
history taking. Year three undergraduates performed poorly in the completeness of diagnosis and control of the
medical condition whereby none of them had a good level of practice. The completeness of records did not differ
between years of study except for diagnosis (p=0.026), control (p<0.001) and updating medical history (p=0.009)
whereby the postgraduates had the best practice. Conclusion: This study highlighted marked deficiencies in taking a
thorough medical history. Adaptation of the European Medical Risk Related History (EMRRH) form is recommended
to be implemented in dental schools.
6.Value of Shock Index in Prognosticating The Short Term Outcome of Death for Patients Presenting With Severe Sepsis and Septic Shock in The Emergency Department
Shah Jahan Mohd Yussof ; Mohd Idzwan Zakaria ; Fatahul Laham Mohamed ; Mohamad Adam Bujang ; Sharmila Lakshmanan ; Abu Hassan Asaari
The Medical Journal of Malaysia 2012;67(4):406-411
Introduction: The importance of early recognition and
treatment of sepsis and its effects on short-term survival
outcome have long been recognized. Having reliable
indicators and markers that would help prognosticate the
survival of these patients is invaluable and would
subsequently assist in the course of effective dynamic
triaging and goal directed management.
Study Objectives: To determine the prognosticative value of
Shock Index (SI), taken upon arrival to the emergency
department and after 2 hours of resuscitation on the shortterm outcome of severe sepsis and septic shock patients.
Methodology: This is a retrospective observational study
involving 50 patients admitted to the University of Malaya
Medical Centre between June 2009 and June 2010 who have
been diagnosed with either severe sepsis or septic shock.
Patients were identified retrospectively from the details
recorded in the registration book of the resuscitation room. 50 patients were selected for this pilot study. The population comprised 19 males (38%) and 31 females (62%). The median (min, max) age was 54.5 (17.0, 84.0) years. The
number of severe sepsis and septic shock cases were 31
(62%), and 19 (38%) respectively. There were 17 (34%) cases
of pneumonias, 13 (26%) cases of urological sepsis, 8 (16%)
cases of gastro intestinal tract related infections and 12
(24%) cases of other infections. There were a total of 23
(46%) survivors and 27 (54%) deaths. The value of the shock
index is defined as systolic blood pressure divided by heart rate was calculated. Shock Index on presentation to ED (SI 1) and after 2 hours of resuscitation in the ED (SI 2). The median, minimum and maximum variables were tested using Mann-Whitney U and Chi square analysis. The significant parameters were re-evaluated for sensitivity, specificity and cut-off points. ROC curves and AUC values were generated among these variables to assess prognostic utility for outcome.
Results: Amongst all 7 variables tested, 2 were tested to be significant (p: < 0.05). From the sensitivity, specificity and ROC analysis, the best predictor for death was (SI 2) with a sensitivity of 80.8%, specificity of 79.2%, AUC value of 0.8894 [CI95 0.8052, 0.9736] at a cut-off point of ≥1.0.
Conclusion: (SI 2) may potentially be utilized as a reliable predictor for death in patients presenting with septic shock and severe sepsis in an emergency department. This parameters should be further analyzed in a larger scale prospective study to determine its validity.


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