1.A comparative study of dynamic versus static rehabilitation protocols after acute Achilles tendon rupture repair with channel assisted minimally invasive repair technique.
Zhonghe WANG ; Lingtong KONG ; Wenhao CAO ; Junjun TANG ; Hongzhe QI ; Meijing DOU ; Haoyu LIU ; Chen CHEN ; Hua CHEN
Chinese Journal of Reparative and Reconstructive Surgery 2024;38(12):1492-1498
OBJECTIVE:
To explore the difference in effectiveness between a dynamic rehabilitation protocol and a traditional static rehabilitation protocol after the treatment of acute Achilles tendon rupture with channel assisted minimally invasive repair (CAMIR) technique through a prospective comparative trial, aiming to provide a reference for clinically selecting a feasible treatment regimen.
METHODS:
Patients with acute Achilles tendon rupture admitted between June 2021 and June 2022 were included in the study, with 60 patients meeting the selection criteria. They were randomly divided into a dynamic rehabilitation group ( n=30) and a static rehabilitation group ( n=30) using a computer-generated random number method. There was no significant difference in baseline data such as gender, age, body mass index, smoking history, injured side, cause of injury, and disease duration between the two groups ( P>0.05). After Achilles tendon anastomosis by using CAMIR technique, the dynamic rehabilitation group implemented early partial weight-bearing training with the assistance of an Achilles heel boot and controlled ankle joint exercises for 6 weeks, while the static rehabilitation group maintained a non-weight-bearing status during this period. Complications in both groups were recorded. At 3 and 6 months after operation, the Achilles tendon total rupture score (ATRS) was used to evaluate the degree of functional limitation of the Achilles tendon in the affected limb, and the 12-Item Short Form Health Survey (SF-12 scale) was used to assess the patients' quality of life, including physical component summary (PCS) and mental component summary (MCS) scores.
RESULTS:
No sural nerve injury occurred during operation in both groups. All patients were followed up 12-18 months (mean, 14 months). The dynamic rehabilitation group had significantly higher ATRS scores at 3 and 6 months after operation compared to the static rehabilitation group ( P<0.05). At 3 months after operation, the dynamic rehabilitation group had significantly lower PCS, MCS, and SF-12 total scores compared to the static rehabilitation group ( P<0.05). At 6 months, all quality of life scores in the two groups were similar ( P>0.05). Two cases (6.6%) in the dynamic rehabilitation group and 5 cases (16.7%) in the static rehabilitation group developed complications, with no significant difference in incidence of complications ( P>0.05).
CONCLUSION
For acute Achilles tendon rupture, the dynamic rehabilitation protocol after Achilles tendon anastomosis by using CAMIR technique can improve early functional recovery and maintains comparable safety and effectiveness compared to static rehabilitation.
Humans
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Achilles Tendon/surgery*
;
Minimally Invasive Surgical Procedures/methods*
;
Rupture/surgery*
;
Female
;
Male
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Tendon Injuries/rehabilitation*
;
Prospective Studies
;
Treatment Outcome
;
Anastomosis, Surgical/methods*
;
Recovery of Function
;
Middle Aged
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Adult
;
Plastic Surgery Procedures/methods*
2.Is oral microbiome of children able to maintain resistance and functional stability in response to short-term interference of ingesta?
Fangqiao WEI ; Xiangyu SUN ; Yufeng GAO ; Haoyu DOU ; Yang LIU ; Lili SU ; Haofei LUO ; Ce ZHU ; Qian ZHANG ; Peiyuan TONG ; Wen REN ; Zhe XUN ; Ruochun GUO ; Yuanlin GUAN ; Shenghui LI ; Yijun QI ; Junjie QIN ; Feng CHEN ; Shuguo ZHENG
Protein & Cell 2021;12(6):502-510
3.Predictive factors of skip metastasis to lateral with leaping central lymph node in papil-lary thyroid carcinoma
HU DAIXING ; ZHOU JING ; SU XINLIANG ; WU KAINAN ; HE WEI ; CAO YIJIA ; REN HAOYU ; MAO YU ; DOU YI ; PENG JIE
Chinese Journal of Clinical Oncology 2017;44(22):1141-1145
Objective:To retrospectively analyze the regularity and risk factors of skip metastasis (central lymph node negative and lat-eral lymph node positive) in papillary thyroid carcinoma (PTC). Methods:A total of 521 PTC patients underwent total thyroidectomy and central plus lateral lymph node dissection at The First Affiliated Hospital of Chongqing Medical University from January 2013 to De-cember 2016. Clinicopathological characteristics of the patients were collected and analyzed. Results:Skip metastasis rate of PTC was 8.3%(43/521). Tumors in the upper lobe (OR=3.401, 95%CI:1.770-6.536;P=0.001) and in the lateral part (OR=3.424, 95%CI:1.182-9.920;P=0.023) of the thyroid, as well as age above 45 (OR=2.856, 95%CI:1.488-5.482;P=0.002), were independent risk factors for skip metastases for this disease. Clinically node-negative (cN0) PTC patients with tumors in the upper lobe had higher possibility of skip metastases than those with clinically involved lateral neck nodes(cN1b) (P=0.022). Conclusion:Skip metastasis of PTC is not un-common. Thus, preoperative clinical assessment and imaging examination for lateral lymph node is necessary, especially for PTC pa-tients who are above 45 years old and with tumors in the upper lobe and/or unilateral area of thyroid. The lateral lymph node dissec-tion should be performed when necessary.

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