Objective:To explore the related factors of non-suicidal self-injury behaviors among sexual and gender minorities.Methods:The database of CNKI,CBM,PubMed,Web of Science,Embase,PsycINFO and CI-NAHLwere retrieved.Software RevMan 5.3 was applied to perform Meta-analysis.Results:A total of 10 articles were included,with a total of 18 520 subjects.Seven factors were included in the meta-analysis.Among them,at-tempted suicide,depression,general victimization and victimization because of sexual and gender minority were riskfactors for non-suicidal self-injury behaviors among sexual and gender minorities(OR=6.50,3.67,1.50,1.48).Care of non-parent adult,parental contact and safe campus environment were protective factors for non-sui-cidal self-injury behaviors among sexual and gender minorities(OR=0.91,0.87,0.75).Conclusion:Sexual and gender minorities who are attempted suicide,with depression,with general victimization and with victimization be-cause of sexual and gender minority identity are more likely to bring about non-suicidal self-injury,and care of non-parent adult,parental contact and safe campus environment can reduce non-suicidal self-injury behaviors among sex-ual and gender minorities.