1.Nutritional support therapy after GLIM criteria may neglect the benefit of reducing infection complications compared with NRS 2002-Re analysis based on a prospective cohort study
Xianna ZHANG ; Haofen XIE ; Zhuo LI ; Bin JIE ; Jingyong XU ; Cheng CHEN ; Weiming KANG ; Xin YE ; Zhuming JIANG
Chinese Journal of Clinical Nutrition 2023;31(2):106-112
The inconsistency of diagnostic criteria for malnutrition has confused clinicians since the 1980s. After the implementation of disease diagnosis related group payment (DRG) in China's public hospitals, the diagnosis of malnutrition and the correct documentation of nutrition-related diagnosis on the front sheet of medical records are related to the correct classification of the disease group and the medical insurance payment. Therefore, the reliable diagnostic criteria for malnutrition, especially disease-related malnutrition, is urgently needed in clinical practice. In September 2018, The global leadership Iinitiative on malnutrition (GLIM) diagnostic criteria consensus was launched. GLIM aimed to provide the explicit and unified diagnostic criteria for malnutrition in adult hospitalized patients. However, GLIM criteria was based on the voting by nutritional experts and was merely a consensus in nature. The clinical validity of GLIM criteria needs prospective verification, i.e., to demonstrate that patients with malnutrition as per GLIM criteria could have improved clinical outcomes with reasonable nutritional interventions. In November 2020, the article titled Nutritional support therapy after GLIM criteria may neglect the benefit of reducing infection complications compared with NRS 2002 was published on the journal Nutrition. It was the first study comparing nutritional risk screening 2002 (NRS 2002) and GLIM malnutrition diagnostic criteria among Chinese patients for the indication of nutritional support therapy. The clinical effectiveness of the two tools was retrospectively verified as well. Here we discussed the key points of this retrospective study, including the critical research methods, to inform the currently ongoing prospective validation of the GLIM malnutrition diagnostic criteria (the item of reduced muscle mass not included).
2.Effect of oral nutrition supplements cluster care in home care of postoperative patients with gastric cancer
Zejun CAI ; Lianying YU ; Qiong CUI ; Haofen XIE ; Dan WU ; Zhilong YAN ; Bin YANG ; Bo FENG
Chinese Journal of Modern Nursing 2023;29(1):51-56
Objective:To construct a cluster care of oral nutrition supplements (ONS) , and to explore its effect in home care of postoperative patients with gastric cancer.Methods:Literature search was conducted to review the status quo of ONS compliance at home in patients with gastric cancer after surgery, and analyze the existing problems. We summarized and formulated the cluster care plan according to the evidence, and established the home ONS management team and process. From November 2020 to October 2021, 107 patients with gastric cancer who needed to implement ONS at home in Gastrointestinal Surgery of Ningbo First Hospital were selected as research objects by convenience sampling. Postoperative patients with gastric cancer from November 2020 to April 2021 were set as the control group ( n=40) , and those from May to October 2021 were set as the observation group ( n=67) . The control group was treated with conventional ONS, and the observation group was treated with home ONS cluster care plan on the basis of the control group. The compliance of nutritional support, weight gain, body mass index increase and follow-up experience between the two groups were evaluated. Results:After six months of intervention, the scores of ONS compliance, weight gain, body mass index increase and follow-up experience in the observation group were significantly higher than those in the control group, and the differences were statistically significant ( P<0.05) . Conclusions:The cluster care plan improves the ONS compliance at home, nutritional status and satisfaction with the follow-up by medical and nursing staff in patients with gastric cancer after surgery, which is worthy of clinical promotion.
3.Nutritional status and quality of life of gastric cancer patients after operation in the context of enhanced recovery
Jingxia QIU ; Xiaofeng WANG ; Qiong CUI ; Haofen XIE ; Zejun CAI ; Zhilong YAN
Chinese Journal of Modern Nursing 2023;29(3):330-335
Objective:To explore the nutritional status and quality of life of gastric cancer patients one month after operation in the context of enhanced recovery, and analyze the correlation between them.Methods:From August 2020 to August 2021, 168 patients discharged from the Gastrointestinal Surgery of Ningbo First Hospital after radical resection of gastric cancer were selected as the study subject by convenience sampling. The Nutritional Risking Screening 2002 (NRS2002) and the Global Leadership Initiative on Malnutrition (GLIM) step 2 (excluding muscle mass measurement index) were used to assess the postoperative nutritional status of patients. The quality of life of patients with gastric cancer after operation was investigated with the European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) . Logistic regression analysis was used to explore the influencing factors of nutritional status of postoperative patients with gastric cancer. A total of 168 questionnaires were distributed, and 168 valid questionnaires were recovered, with a valid recovery rate of 100.0%.Results:A total of 104 patients (61.9%) had nutritional risk and 46 patients (27.4%) had malnutrition. There were statistical differences in age, education level, tumor stage, body mass index, physical function, role function, emotional function, cognitive function, general health, fatigue, nausea and vomiting, and loss of appetite among gastric cancer patients with different nutritional status after operation ( P<0.05) . Logistic regression analysis showed that body mass index, physical function, role function, emotional function and fatigue were the influencing factors of the nutritional status of patients one month after operation ( P<0.05) . Conclusions:In the context of enhanced recovery, the nutritional risk and malnutrition rate of gastric cancer patients one month after operation are high, and are closely related to the quality of life. When implementing enhanced recovery after surgery, medical and nursing staff should strengthen and optimize the nutrition management of gastric cancer patients before hospital, during perioperative period and after discharge, improve the nutritional status after operation and the quality of life of patients.
4.Evidence-based nursing practice of early enteral nutrition support after gastric cancer surgery
Jie WANG ; Haichao LI ; Dan WU ; Haofen XIE ; Yao YAO ; Qinhong XU ; Liang YANG ; Zejun CAI ; Xiaoyan HUANG
Chinese Journal of Modern Nursing 2023;29(29):4012-4017
Objective:To summarize the best evidence for early enteral nutrition support in postoperative patients with gastric cancer and evaluate its effectiveness.Methods:From March to August 2021, 108 postoperative patients with gastric cancer admitted to the Gastrointestinal Surgery of the First Affiliated Hospital of Ningbo University were selected. We applied evidence-based nursing methods to summarize the best evidence for early enteral nutrition support in postoperative gastric cancer patients, and constructed and implemented the best evidence application strategy through baseline review, evaluation of evidence application clinical scenarios and barriers. We compared the various indicators of two groups of patients before the application of evidence (March to May 2021, n=55) and after the application of evidence (June to August 2021, n=53) . Results:No adverse events occurred during the application of evidence. After applying evidence, the correct nutritional assessment rate increased from 41.82% (23/55) at baseline review to 90.57% (48/53), the implementation rate of early postoperative enteral nutrition increased from 0 to 45.28% (24/53), the start time of postoperative enteral nutrition shortened from (3.75±2.33) days to (2.06±1.38) days, and the implementation rate of postoperative priority oral nutrition increased from 63.64% (35/55) to 86.79% (46/53), nutritional related complications decreased from 40.00% (22/55) to 20.75% (11/53), and the differences were all statistically significant ( P<0.05) . Conclusions:The application of the best evidence for early enteral nutrition support in postoperative gastric cancer patients can shorten the start time of postoperative enteral nutrition, reduce postoperative nutrition related complications, and promote early recovery of patients.
5.Evidence summary for early enteral nutrition support in patients after gastric cancer surgery
Yao YAO ; Jie WANG ; Haifeng ZHAO ; Haofen XIE ; Qinhong XU ; Zejun CAI ; Zhilong YAN ; Xiaoyan HUANG
Chinese Journal of Modern Nursing 2022;28(14):1869-1875
Objective:To retrieve relevant evidence for early enteral nutrition support in patients after gastric cancer surgery and summarize the best evidence, so as to provide evidence-based evidence for clinical implementation of postoperative enteral nutrition management for gastric cancer.Methods:Evidence-based questions were established according to PIPOST principles, UpToDate, Cochrane Library, Joanna Briggs Institute Library, BMJ Best Practice, Agency for Healthcare Research and Quality website, Medlive, European Society for Clinical Nutrition and Metabolism website, American Society for Parenteral and Enteral Nutrition website, Embase, Medline, PubMed, SinoMed, Wanfang Database, China National Knowledge Infrastructure were searched according to the "6S" evidence model. The retrieval period of every database was from January 1, 2016 to May 31, 2021. The Evidence Pre-Grading and Evidence Recommendation Grading System (2014) of Australian Joanna Briggs Institute Evidence-Based Health Care Center was used to extract evidence from the literature that met the quality standards, determine the evidence grading and recommendation level and form the best evidence.Results:A total of 317 literatures were retrieved, and 10 literatures were included, including 1 guideline, 4 expert consensus and 5 systematic reviews. The 10 evidences were summarized from 4 aspects, including indication evaluation, timing management, route and preparation management and risk management.Conclusions:Current evidence shows that early enteral nutrition is safe and feasible in patients after gastric cancer surgery. In the process of implementing enteral nutrition, medical staff should fully evaluate the indications and needs of patients and make clear and prudent choices for nutritional support channels and preparations of patients, so as to form the best evidence and clinical management programs for early enteral nutrition support for patients after gastric cancer surgery and accelerate postoperative recovery of patients.
6.Correlation analysis of discharge readiness and nutritional status in patients with gastric cancer in the context of enhanced recovery after surgery
Jingxia QIU ; Lili MA ; Renhui HONG ; Haofen XIE ; Zejun CAI ; Zhilong YAN
Chinese Journal of Modern Nursing 2022;28(15):2051-2056
Objective:To investigate the relationship between discharge readiness and nutritional status of patients undergoing gastric cancer surgery in the context of enhanced recovery after surgery (ERAS) , so as to provide individualized guidance for patients after discharge.Methods:Using the convenient sampling method, a total of 120 patients who underwent radical gastrectomy for gastric cancer from June 2020 to June 2021 in Ningbo First Hospital were selected as research objects, and they all received ERAS nursing care. One day before discharge, Nutritional Risk Screening Table and Discharge Readiness Scale were used for questionnaire analysis.Results:The total score of discharge readiness of 120 patients with gastric cancer after surgery was (81.42±6.87) . Among the three dimensions, personal status was (19.65±2.19) , adaptability was (29.67±3.10) and anticipatory support was (32.10±2.61) . 57.5% (69/120) of gastric cancer patients discharged from hospital had nutritional risk. The scores of hospital discharge readiness and the scores of each dimension in the nutritional risk group were lower than those in the non-nutritional risk group, and the differences were statistically significant ( P<0.05) . Multivariate analysis showed that nutritional status was an influencing factor for the total score of hospital discharge readiness in patients with gastric cancer surgery (standardized regression coefficient was 0.321, P<0.05) . Conclusions:Under the background of ERAS, the discharge readiness of patients after gastric cancer surgery is at a moderate level, postoperative patients are generally at nutritional risk and the discharge readiness of patients with nutritional risk is lower than that of patients without nutritional risk. Perioperative nutrition management by nursing staff can improve the discharge readiness of patients undergoing gastric cancer surgery, and continuous nutrition management should be carried out for discharged patients with nutritional risk, in order to promote home rehabilitation of patients with gastric cancer surgery.
7.Effects of sarcopenia on physical performance and nutritional status in elderly patients with gastrointestinal tumors
Jingxia QIU ; Yanjuan LIN ; Xuefeng WANG ; Haofen XIE ; Zejun CAI ; Zhilong YAN ; Bin YANG
Chinese Journal of Clinical Nutrition 2022;30(3):134-140
Objective:To investigate the effect of sarcopenia on physical performance and nutritional status in elderly patients with gastrointestinal tumors.Methods:a total of 120 eligible in-patients were enrolled from gastrointestinal surgery department of a Grade A tertiary hospital in Ningbo city from September 2021 to January 2022. General clinical data were collected, nutritional risk was screened using Nutritional Risk Screening 2002 (NRS 2002), physical performance was assessed by Short Physical Performance Battery (SPPB), skeletal muscle index at the third lumbar vertebra level (L3 SMI) was calculated using abdominal CT scan, and grip strength/muscle strength, gait speed by 6 Meter Timed Walk Test and calf circumference were measured. Subjects were divided into sarcopenia and non-sarcopenia group according to the diagnostic criteria of the Asian Working Group for Sarcopenia (AWGS). Impacting factors of sarcopenia and the correlation between muscle mass and physical performance in elderly patients with gastrointestinal tumors were analyzed.Results:The overall prevalence rate of sarcopenia in elderly patients with gastrointestinal tumors was 28.3% (34/120) and it was 28.9% (22/76) and 27.3% (12/44) in males and females respectively. There were statistically significant differences in age, tumor stage, nutritional risk, body mass index, calf circumference, L3 SMI, grip strength/muscle strength, gait speed and SPPB score between patients with and without sarcopenia (P<0.05). Muscle strength/grip strength, L3 SMI and gait speed were closely correlated with the occurrence of sarcopenia in elderly patients with gastrointestinal tumors (P<0.05). The L3 SMI was positively correlated with physical performance as assessed with SPPB in both groups.Conclusions:Sarcopenia is a common complication in elderly patients with gastrointestinal tumors with multiple influencing factors. Timely nutritional intervention and exercise intervention should be incorporated into the treatment of elderly gastrointestinal tumor patients with sarcopenia in order to improve nutrition status.
8.Reason and inner experience of the patient's cancellation of day surgery: a qualitative study
Haofen XIE ; Zejun CAI ; Hui FEI ; Hong ZHU ; Qiaonyu CHEN ; Jie WANG ; Xianna ZHANG
Chinese Journal of Modern Nursing 2021;27(13):1706-1710
Objective:To deeply understand the reason and inner experience of day surgery patients canceling surgery through qualitative research, so as to strengthen the management of day surgery patients.Methods:This research adopted phenomenological research method. From June to December 2019, purpose sampling was used to select 12 patients who had canceled the day surgery at Ningbo First Hospital in Zhejiang Province for a semi-structured interview. The Colaizzi 7-step analysis method was used for data analysis.Results:Through repeated refining, analysis and extraction of interview data, the reasons and inner experience of day surgery patients who canceled surgery were finally summarized into 5 themes. Those themes included fear of day surgery, distrust of day doctors, affected by basic diseases and physiological factors, lack of confidence in community medical care, insufficient preparation before surgery.Conclusions:The reasons for day surgery patients to cancel surgery include fear of surgery, distrust of doctors, basic diseases and physiological factors, lack of confidence in community medical care, and insufficient preparation before surgery. It is recommended that day surgery medical and nursing staff strengthen day ward management, improve their professional level and ability to communicate with patients, and at the same time promote the construction of hospital-community integration to ensure the medical safety of patients after discharge from the hospital, and further reduce the cancellation rate of day surgery.
9.Application of evidence-based clinical practice of enhanced recovery after surgery multiple discrepancies theory model in nursing of patients undergoing hepatectomy
Jie WANG ; Liyan PEI ; Yanan LU ; Haofen XIE ; Zejun CAI ; Hui FEI ; Hong ZHU ; Qiaonyu CHEN ; Liang YANG
Chinese Journal of Modern Nursing 2021;27(14):1883-1888
Objective:To explore the application effect of evidence-based clinical practice of enhanced recovery after surgery multiple discrepancies theory (ERAS-MDT) in perioperative nursing of patients with hepatectomy.Methods:From January to December 2018, 62 patients with hepatectomy who received perioperative care of ERAS-MDT in the Department of Hepatobiliary and Pancreatic Surgery of Ningbo First Hospital of Zhejiang Province were selected as the control group. We reviewed the implementation effect, searched the clinical practice guidelines, systematic reviews and evidence summary related to ERAS-MDT, carried out field investigation and expert consultation, summarized the obstacle factors, formulated countermeasures, and built a standardized operation mode of ERAS-MDT. From January to December 2019, a total of 66 patients with hepatectomy who received standardized ERAS-MDT perioperative nursing were selected as the observation group. The first exhaust time, defecation time, first ambulation time, first oral feeding time, hospitalization time, nutritional status and pain score were compared between the two groups.Results:The first exhaust time, defecation time, first ambulation time, first oral feeding time, hospitalization time of the observation group were earlier than those of the control group, and the differences were statistically significant ( P<0.05) . The albumin level of the observation group was higher than that of the control group, and the difference was statistically significant ( P<0.05) . The pain scores of the observation group on the operation day was lower than those of the control group, and the difference between the two groups was statistically significant ( P<0.05) . Conclusions:A standardized management model of ERSA-MDT based on evidence-based clinical practice exhibits positive effect on the perioperative recovery of hepatectomy patients, which can further improve the clinical outcome of patients.
10.The application of structure-process-outcome three-dimensional quality evaluation model in daytime operation management of patients undergoing digital subtraction angiography
Jingmi WU ; Liyan ZHANG ; Ping ZHANG ; Haofen XIE
Chinese Journal of Modern Nursing 2021;27(21):2858-2862
Objective:To explore the effects of Donabedian's structure-process-outcome three-dimensional quality evaluation model in the quality management of daytime surgery for patients undergoing digital subtraction angiography (WBDSA) .Methods:The patients who underwent daytime DSA at Ningbo First Hospital in Zhejiang Province from October 2019 to October 2020 were selected as the research subjects, with 61 patients admitted from October 2019 to April 2020 included into a control group, and 65 patients admitted from May to October 2020 included into an observation group. Patients in the control group received routine daytime operation management, while patients in the observation group underwent daytime operation management based on a structure-process-outcome three-dimensional quality evaluation model. The incidence of complications, ≥ 2 times reexamination rate and patient satisfaction were compared between the two groups.Results:There was no significant difference in the incidence of complications at the puncture site and non-puncture site between the two groups ( P>0.05) . The rate of ≥ 2 reexamination in the observation group was 21.54% (14/65) , which was higher than 8.20% (5/61) in the control group, and the difference was statistically significant ( P<0.05) . The patient satisfaction in the observation group was (99.04±2.10) , which was higher than (96.93±2.95) in the control group, and the difference was statistically significant ( P<0.05) . Conclusions:The daytime operation management model based on Donabedian three-dimensional quality evaluation model can improve the compliance of reexamination and satisfaction of patients undergoing DSA.

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