1.Research progress on the pharmacological mechanism of Rehmannia glutinosa in diabetic kidney disease
Di NIU ; Ruifang CHEN ; Xinmeng HUANG ; Changchang LI ; Hansong ZHOU ; Xinxin PANG
China Pharmacy 2025;36(23):2995-3000
Diabetic kidney disease (DKD) is one of the most common and harmful microvascular complications of diabetes, and there is currently a lack of effective treatment methods to delay its progression. Traditional Chinese medicine has a long history of treating DKD and offers unique advantages. As a traditional Chinese medicine, Rehmannia glutinosa has shown potential in the treatment of DKD in clinical and modern pharmacological research. After integrating relevant research on the pharmacological mechanism of R. glutinosa in treating DKD, it has been found that the main active components of R. glutinosa, such as catalpol, rehmannioside D, aucubin, verbascoside, salidroside, echinacoside and R. glutinosa polysaccharides, along with its extracts and compounds (such as Liuwei dihuang pills, Shenqi dihuang decoction, and Shenqi pills), can exert multiple effects by intervening in various signaling pathways, including advanced glycation end product (AGE)/receptor for AGE, nuclear factor kappa-B (NF- κB), and transforming growth factor-β1 (TGF-β1)/Smads. These effects include ameliorating metabolic disorders and oxidative stress in DKD, inhibiting the processes of renal inflammation and fibrosis, regulating cell death modalities including apoptosis and ferroptosis, as well as autophagy, and reshaping the gut microbiota. Consequently, it can improve physical and chemical indices and renal tissue pathological damage, thus delaying the progression of DKD.
2.Curative effect of autologous periosteal iliac bone graft and allogeneic bone powder combined with PRP on HeppleⅤ talus osteochondral injury
Suqi WU ; Hansong WU ; Dongmei YU ; Qiong CHEN ; Rongrong CHI
China Modern Doctor 2024;62(5):40-43
Objective To analyze and compare the treatment of HeppleⅤ talus osteochondral injury(OLT)with autologous periosteal iliac bone graft and allogeneic bone powder combined with platelet rich gel(PRP).Methods Totally 62 HeppleⅤOLT patients admitted to our hospital from October 2018 to October 2022 were selected as the research subjects.They were divided into a transplantation group(31 patients received autologous periosteal iliac bone transplantation treatment)and a combination group(31 patients received allogeneic bone powder combined with PRP treatment)based on their treatment methods.Conduct a 12 month postoperative outpatient follow-up study on patients,evaluate and compare the treatment effectiveness,ankle joint range of motion(ROM),American Society of Orthopedic Foot and Ankle Surgeons(AOFAS)ankle posterior foot score,pain score,satisfaction,and incidence of complications between the two groups of patients at 12 months after surgery.Results The total effective rate of the transplantation group(96.77%)was not significantly different from that of the combination group(93.55%,P>0.05).At 12 months after surgery,the ROM and AOFAS scores of both groups improved(P<0.05),and there was no statistically significant difference between the groups(P>0.05).At 1 month,3 months,6 months,and 12 months after surgery,the pain scores of both groups decreased compared to before surgery(P<0.05).The subjective overall satisfaction of patients in the transplantation group(77.42%)was lower than that in the combination group(96.77%,P<0.05).The total incidence of complications in the transplantation group(19.35%)was significantly higher than that in the combination group(3.23%,P<0.05).Conclusion Allogeneic bone powder combined with PRP can avoid additional surgical incisions,increase patient subjective satisfaction,and increase the incidence of postoperative complications.
3.Research on the Construction Scenarios and Evaluation of Pediatric Smart Wards
Siyuan SHEN ; Jiali YU ; Zhijun CHEN ; Hansong WANG
Chinese Hospital Management 2024;44(10):70-73
Objective To explore the feasibility,importance,and pediatric characteristics of the construction modules and scenarios of pediatric smart wards,as well as the priority level of construction in different scenarios,in order to provide a basis for the phased construction of pediatric smart ward scenarios.Methods A systematic evaluation of the scenario construction of smart wards was conducted through literature review,key informant surveys.Results By systematically scoring and ranking the construction of 15 projects and 57 application scenarios under the three modules of smart management,smart services,and smart healthcare,it is clear that in the practice of pediatric smart wards,priority should be given to the construction of certain scenarios based on the high and low scores and actual conditions,and gradually promote the construction of other scenarios.Conclusion The pediatric smart ward scene has both the universality of traditional smart ward construction needs and its own disciplinary characteristics.Therefore,in the construction process,it is necessary to widely understand the actual needs and carry out targeted smart scene construction that is in line with pediatric characteristics.
4.Research on the Construction Scenarios and Evaluation of Pediatric Smart Wards
Siyuan SHEN ; Jiali YU ; Zhijun CHEN ; Hansong WANG
Chinese Hospital Management 2024;44(10):70-73
Objective To explore the feasibility,importance,and pediatric characteristics of the construction modules and scenarios of pediatric smart wards,as well as the priority level of construction in different scenarios,in order to provide a basis for the phased construction of pediatric smart ward scenarios.Methods A systematic evaluation of the scenario construction of smart wards was conducted through literature review,key informant surveys.Results By systematically scoring and ranking the construction of 15 projects and 57 application scenarios under the three modules of smart management,smart services,and smart healthcare,it is clear that in the practice of pediatric smart wards,priority should be given to the construction of certain scenarios based on the high and low scores and actual conditions,and gradually promote the construction of other scenarios.Conclusion The pediatric smart ward scene has both the universality of traditional smart ward construction needs and its own disciplinary characteristics.Therefore,in the construction process,it is necessary to widely understand the actual needs and carry out targeted smart scene construction that is in line with pediatric characteristics.
5.Research on the Construction Scenarios and Evaluation of Pediatric Smart Wards
Siyuan SHEN ; Jiali YU ; Zhijun CHEN ; Hansong WANG
Chinese Hospital Management 2024;44(10):70-73
Objective To explore the feasibility,importance,and pediatric characteristics of the construction modules and scenarios of pediatric smart wards,as well as the priority level of construction in different scenarios,in order to provide a basis for the phased construction of pediatric smart ward scenarios.Methods A systematic evaluation of the scenario construction of smart wards was conducted through literature review,key informant surveys.Results By systematically scoring and ranking the construction of 15 projects and 57 application scenarios under the three modules of smart management,smart services,and smart healthcare,it is clear that in the practice of pediatric smart wards,priority should be given to the construction of certain scenarios based on the high and low scores and actual conditions,and gradually promote the construction of other scenarios.Conclusion The pediatric smart ward scene has both the universality of traditional smart ward construction needs and its own disciplinary characteristics.Therefore,in the construction process,it is necessary to widely understand the actual needs and carry out targeted smart scene construction that is in line with pediatric characteristics.
6.Research on the Construction Scenarios and Evaluation of Pediatric Smart Wards
Siyuan SHEN ; Jiali YU ; Zhijun CHEN ; Hansong WANG
Chinese Hospital Management 2024;44(10):70-73
Objective To explore the feasibility,importance,and pediatric characteristics of the construction modules and scenarios of pediatric smart wards,as well as the priority level of construction in different scenarios,in order to provide a basis for the phased construction of pediatric smart ward scenarios.Methods A systematic evaluation of the scenario construction of smart wards was conducted through literature review,key informant surveys.Results By systematically scoring and ranking the construction of 15 projects and 57 application scenarios under the three modules of smart management,smart services,and smart healthcare,it is clear that in the practice of pediatric smart wards,priority should be given to the construction of certain scenarios based on the high and low scores and actual conditions,and gradually promote the construction of other scenarios.Conclusion The pediatric smart ward scene has both the universality of traditional smart ward construction needs and its own disciplinary characteristics.Therefore,in the construction process,it is necessary to widely understand the actual needs and carry out targeted smart scene construction that is in line with pediatric characteristics.
7.Research on the Construction Scenarios and Evaluation of Pediatric Smart Wards
Siyuan SHEN ; Jiali YU ; Zhijun CHEN ; Hansong WANG
Chinese Hospital Management 2024;44(10):70-73
Objective To explore the feasibility,importance,and pediatric characteristics of the construction modules and scenarios of pediatric smart wards,as well as the priority level of construction in different scenarios,in order to provide a basis for the phased construction of pediatric smart ward scenarios.Methods A systematic evaluation of the scenario construction of smart wards was conducted through literature review,key informant surveys.Results By systematically scoring and ranking the construction of 15 projects and 57 application scenarios under the three modules of smart management,smart services,and smart healthcare,it is clear that in the practice of pediatric smart wards,priority should be given to the construction of certain scenarios based on the high and low scores and actual conditions,and gradually promote the construction of other scenarios.Conclusion The pediatric smart ward scene has both the universality of traditional smart ward construction needs and its own disciplinary characteristics.Therefore,in the construction process,it is necessary to widely understand the actual needs and carry out targeted smart scene construction that is in line with pediatric characteristics.
8.Research on the Construction Scenarios and Evaluation of Pediatric Smart Wards
Siyuan SHEN ; Jiali YU ; Zhijun CHEN ; Hansong WANG
Chinese Hospital Management 2024;44(10):70-73
Objective To explore the feasibility,importance,and pediatric characteristics of the construction modules and scenarios of pediatric smart wards,as well as the priority level of construction in different scenarios,in order to provide a basis for the phased construction of pediatric smart ward scenarios.Methods A systematic evaluation of the scenario construction of smart wards was conducted through literature review,key informant surveys.Results By systematically scoring and ranking the construction of 15 projects and 57 application scenarios under the three modules of smart management,smart services,and smart healthcare,it is clear that in the practice of pediatric smart wards,priority should be given to the construction of certain scenarios based on the high and low scores and actual conditions,and gradually promote the construction of other scenarios.Conclusion The pediatric smart ward scene has both the universality of traditional smart ward construction needs and its own disciplinary characteristics.Therefore,in the construction process,it is necessary to widely understand the actual needs and carry out targeted smart scene construction that is in line with pediatric characteristics.
9.Research on the Construction Scenarios and Evaluation of Pediatric Smart Wards
Siyuan SHEN ; Jiali YU ; Zhijun CHEN ; Hansong WANG
Chinese Hospital Management 2024;44(10):70-73
Objective To explore the feasibility,importance,and pediatric characteristics of the construction modules and scenarios of pediatric smart wards,as well as the priority level of construction in different scenarios,in order to provide a basis for the phased construction of pediatric smart ward scenarios.Methods A systematic evaluation of the scenario construction of smart wards was conducted through literature review,key informant surveys.Results By systematically scoring and ranking the construction of 15 projects and 57 application scenarios under the three modules of smart management,smart services,and smart healthcare,it is clear that in the practice of pediatric smart wards,priority should be given to the construction of certain scenarios based on the high and low scores and actual conditions,and gradually promote the construction of other scenarios.Conclusion The pediatric smart ward scene has both the universality of traditional smart ward construction needs and its own disciplinary characteristics.Therefore,in the construction process,it is necessary to widely understand the actual needs and carry out targeted smart scene construction that is in line with pediatric characteristics.
10.Research on the Construction Scenarios and Evaluation of Pediatric Smart Wards
Siyuan SHEN ; Jiali YU ; Zhijun CHEN ; Hansong WANG
Chinese Hospital Management 2024;44(10):70-73
Objective To explore the feasibility,importance,and pediatric characteristics of the construction modules and scenarios of pediatric smart wards,as well as the priority level of construction in different scenarios,in order to provide a basis for the phased construction of pediatric smart ward scenarios.Methods A systematic evaluation of the scenario construction of smart wards was conducted through literature review,key informant surveys.Results By systematically scoring and ranking the construction of 15 projects and 57 application scenarios under the three modules of smart management,smart services,and smart healthcare,it is clear that in the practice of pediatric smart wards,priority should be given to the construction of certain scenarios based on the high and low scores and actual conditions,and gradually promote the construction of other scenarios.Conclusion The pediatric smart ward scene has both the universality of traditional smart ward construction needs and its own disciplinary characteristics.Therefore,in the construction process,it is necessary to widely understand the actual needs and carry out targeted smart scene construction that is in line with pediatric characteristics.

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