1.Clinical research report on Chinese patent medicines and classic traditional Chinese medicine prescriptions (2023)
Xiaolei WU ; Haiyin HU ; Yuetong WANG ; Fauci Alice Josephine ; Yazi ZHANG ; Wenting SONG ; Fengwen YANG ; Boli ZHANG ; Junhua ZHANG ; Zhaochen JI
Digital Chinese Medicine 2025;8(2):123-136
Objective:
Randomized controlled trials (RCTs) of Chinese patent medicines and classic traditional Chinese medicine prescriptions were systematically reviewed from both Chinese and English journals published in 2023. A preliminary summary and evaluation were conducted on the generation and translation of clinical evidence for these treatments. This analysis aims to inform future research on clinical efficacy evaluation and guide the rational application of evidence.
Methods:
RCTs of Chinese patent medicines and classic traditional Chinese prescriptions published in 2023 were comprehensively retrieved from the Artificial Intelligence Clinical Evidence Database for Chinese Patent Medicine (AICED-CPM), with supplementary searches conducted in China National Knowledge Infrastructure (CNKI), Wanfang Data, Chinese Science and Technology Journal Database (VIP), Chinese Biomedical Literature Database (SinoMed), Cochrane Library, PubMed, Embase, and Web of Science. The study characteristics and methodological quality of these RCTs were systematically analyzed and evaluated.
Results:
A total of 1 443 RCTs of Chinese patent medicines were included, comprising 1 399 Chinese articles and 44 English articles. Additionally, 334 RCTs of classic traditional Chinese medicine prescriptions were found, with 331 published in Chinese and 3 in English. 196 567 participants were included, covering 585 types of Chinese patent medicines (487 oral, 61 injectable, and 37 topical) and 179 classic traditional Chinese medicine prescriptions. The involved studies encompassed 22 types of diseases, with research primarily focusing on diseases of the circulatory system, the respiratory system, and the genitourinary system. The sample sizes ranged from 18 to 3 777 participants, and most studies were conducted at a single center. Methodologically, the implementation of allocation concealment and blinding remained insufficiently emphasized.
Conclusion
Overall, compared with 2022, both the number of RCT publications and their methodological quality have improved in 2023, with heightened attention to research on diseases of the genitourinary system. However, quality control and standardized management in the design and implementation processes still require enhancement to produce more high-quality clinical evidence and accelerate the translation and application of this evidence.
2.Research on Governance of Medical Service Price Coordination in the Yangtze River Delta Region from the Perspective of Social Network Analysis
Juan LI ; Liang FANG ; Haiyin WANG ; Chunlin JIN
Chinese Health Economics 2024;43(6):75-78
Objective:To explore the structural characteristics of the medical service price network in the Yangtze River Delta,and provide a new management perspective for the collaborative governance of medical service prices in the Yangtze River Delta.Methods:Taking the related medical security bureaus of some core cities in the Yangtze River Delta as samples,based on the social network analysis method,the structural characteristics of price linkage network are analyzed from the perspectives of network density and correlation,individual centrality and block model analysis.Results:Firstly,the price network is not tight and has poor stability;secondly,the price network is unbalanced,with the Municipal Medical Insurance Bureau playing different roles;thirdly,the price network has obvious spatial aggregation and spatial spillover.Conclusion:The overall situation of the medical service price linkage network is not optimistic,and the network advantages should be fully integrated to promote the coordinated development of medical service prices in the Yangtze River Delta Region.
3.International Practice and Insights on the Medical Insurance Access Mechanism of Medical Service Item Based on HTA
Chenxi ZHANG ; Haiyin WANG ; Xin LIU ; Chunlin JIN
Chinese Health Economics 2024;43(9):92-96
Objective:To discuss how to construct the medical insurance access for medical service items based on Health Tech-nology Assessment(HTA)applicable to China.Methods:This study consolidated the current medical insurance access in some prov-inces and cities from China and identified deficiencies through the expert interview.We summarized the experience and indicators contained in the HTA report in UK and Singapore by using literature analysis.Results:In most regions of China,the management of medical services price is gradually moving from exclusion items based on certain conditions to access approach,lacking of tools for assessment.In UK and Singapore,the medical insurance access mechanism mainly consists of subject selection,scoping,HTA imple-mentation and decision-making,in the HTA report,with the data including clinical evidence,cost evidence and budget impact on health system,etc.Conclusion:Building an evidence-based health policy decision-making framework through multi-criteria deci-sion analysis and the construction of medical insurance access mechanism based on HTA can be achieved by developing national guidelines,multi-scenario HTA systems,and enhancing the supervision on the process of HTA.
4.Progress of Theoretical and Empirical Research on ICER Thresholds in China and Its Enlightenment
Chenxi ZHANG ; Haiyin WANG ; Chunlin JIN
Chinese Health Economics 2024;43(11):32-34,40
Objective:To provide suggestions for exploring the ICER threshold's calculation method and reasonable estimation in China.Methods:It summarizes the consensus and analyze the disputes on thresholds in China based on theoretical and empirical research by literature review,compares the thresholds derived from willingness to pay versus opportunity cost methods.Results:Theoretical researches on threshold of China mainly focus on method for calculation,health output index,and health equity,etc.The controversy persists over the threshold's characteristics.The health care demand-side perspective willingness-to-pay method was the most widely used in the empirical studies,but the results of the thresholds measured by this method varied widely;the thresholds measured by the health care supply-side perspective opportunity cost method were lower than the thresholds obtained from the demand-side perspective.Conclusion:It is still essential to discuss the threshold's characteristics and establish the methods framework complementing both demand and supply side for Chinese health insurance,and to standardize and normalize the measurement methods,as well as to set up multi-level thresholds according to the preferences of the population,the severity of the disease,and so on,in order to take into account both economy and equity.
5.Research on Governance of Medical Service Price Coordination in the Yangtze River Delta Region from the Perspective of Social Network Analysis
Juan LI ; Liang FANG ; Haiyin WANG ; Chunlin JIN
Chinese Health Economics 2024;43(6):75-78
Objective:To explore the structural characteristics of the medical service price network in the Yangtze River Delta,and provide a new management perspective for the collaborative governance of medical service prices in the Yangtze River Delta.Methods:Taking the related medical security bureaus of some core cities in the Yangtze River Delta as samples,based on the social network analysis method,the structural characteristics of price linkage network are analyzed from the perspectives of network density and correlation,individual centrality and block model analysis.Results:Firstly,the price network is not tight and has poor stability;secondly,the price network is unbalanced,with the Municipal Medical Insurance Bureau playing different roles;thirdly,the price network has obvious spatial aggregation and spatial spillover.Conclusion:The overall situation of the medical service price linkage network is not optimistic,and the network advantages should be fully integrated to promote the coordinated development of medical service prices in the Yangtze River Delta Region.
6.International Practice and Insights on the Medical Insurance Access Mechanism of Medical Service Item Based on HTA
Chenxi ZHANG ; Haiyin WANG ; Xin LIU ; Chunlin JIN
Chinese Health Economics 2024;43(9):92-96
Objective:To discuss how to construct the medical insurance access for medical service items based on Health Tech-nology Assessment(HTA)applicable to China.Methods:This study consolidated the current medical insurance access in some prov-inces and cities from China and identified deficiencies through the expert interview.We summarized the experience and indicators contained in the HTA report in UK and Singapore by using literature analysis.Results:In most regions of China,the management of medical services price is gradually moving from exclusion items based on certain conditions to access approach,lacking of tools for assessment.In UK and Singapore,the medical insurance access mechanism mainly consists of subject selection,scoping,HTA imple-mentation and decision-making,in the HTA report,with the data including clinical evidence,cost evidence and budget impact on health system,etc.Conclusion:Building an evidence-based health policy decision-making framework through multi-criteria deci-sion analysis and the construction of medical insurance access mechanism based on HTA can be achieved by developing national guidelines,multi-scenario HTA systems,and enhancing the supervision on the process of HTA.
7.Progress of Theoretical and Empirical Research on ICER Thresholds in China and Its Enlightenment
Chenxi ZHANG ; Haiyin WANG ; Chunlin JIN
Chinese Health Economics 2024;43(11):32-34,40
Objective:To provide suggestions for exploring the ICER threshold's calculation method and reasonable estimation in China.Methods:It summarizes the consensus and analyze the disputes on thresholds in China based on theoretical and empirical research by literature review,compares the thresholds derived from willingness to pay versus opportunity cost methods.Results:Theoretical researches on threshold of China mainly focus on method for calculation,health output index,and health equity,etc.The controversy persists over the threshold's characteristics.The health care demand-side perspective willingness-to-pay method was the most widely used in the empirical studies,but the results of the thresholds measured by this method varied widely;the thresholds measured by the health care supply-side perspective opportunity cost method were lower than the thresholds obtained from the demand-side perspective.Conclusion:It is still essential to discuss the threshold's characteristics and establish the methods framework complementing both demand and supply side for Chinese health insurance,and to standardize and normalize the measurement methods,as well as to set up multi-level thresholds according to the preferences of the population,the severity of the disease,and so on,in order to take into account both economy and equity.
8.Research on Governance of Medical Service Price Coordination in the Yangtze River Delta Region from the Perspective of Social Network Analysis
Juan LI ; Liang FANG ; Haiyin WANG ; Chunlin JIN
Chinese Health Economics 2024;43(6):75-78
Objective:To explore the structural characteristics of the medical service price network in the Yangtze River Delta,and provide a new management perspective for the collaborative governance of medical service prices in the Yangtze River Delta.Methods:Taking the related medical security bureaus of some core cities in the Yangtze River Delta as samples,based on the social network analysis method,the structural characteristics of price linkage network are analyzed from the perspectives of network density and correlation,individual centrality and block model analysis.Results:Firstly,the price network is not tight and has poor stability;secondly,the price network is unbalanced,with the Municipal Medical Insurance Bureau playing different roles;thirdly,the price network has obvious spatial aggregation and spatial spillover.Conclusion:The overall situation of the medical service price linkage network is not optimistic,and the network advantages should be fully integrated to promote the coordinated development of medical service prices in the Yangtze River Delta Region.
9.International Practice and Insights on the Medical Insurance Access Mechanism of Medical Service Item Based on HTA
Chenxi ZHANG ; Haiyin WANG ; Xin LIU ; Chunlin JIN
Chinese Health Economics 2024;43(9):92-96
Objective:To discuss how to construct the medical insurance access for medical service items based on Health Tech-nology Assessment(HTA)applicable to China.Methods:This study consolidated the current medical insurance access in some prov-inces and cities from China and identified deficiencies through the expert interview.We summarized the experience and indicators contained in the HTA report in UK and Singapore by using literature analysis.Results:In most regions of China,the management of medical services price is gradually moving from exclusion items based on certain conditions to access approach,lacking of tools for assessment.In UK and Singapore,the medical insurance access mechanism mainly consists of subject selection,scoping,HTA imple-mentation and decision-making,in the HTA report,with the data including clinical evidence,cost evidence and budget impact on health system,etc.Conclusion:Building an evidence-based health policy decision-making framework through multi-criteria deci-sion analysis and the construction of medical insurance access mechanism based on HTA can be achieved by developing national guidelines,multi-scenario HTA systems,and enhancing the supervision on the process of HTA.
10.Progress of Theoretical and Empirical Research on ICER Thresholds in China and Its Enlightenment
Chenxi ZHANG ; Haiyin WANG ; Chunlin JIN
Chinese Health Economics 2024;43(11):32-34,40
Objective:To provide suggestions for exploring the ICER threshold's calculation method and reasonable estimation in China.Methods:It summarizes the consensus and analyze the disputes on thresholds in China based on theoretical and empirical research by literature review,compares the thresholds derived from willingness to pay versus opportunity cost methods.Results:Theoretical researches on threshold of China mainly focus on method for calculation,health output index,and health equity,etc.The controversy persists over the threshold's characteristics.The health care demand-side perspective willingness-to-pay method was the most widely used in the empirical studies,but the results of the thresholds measured by this method varied widely;the thresholds measured by the health care supply-side perspective opportunity cost method were lower than the thresholds obtained from the demand-side perspective.Conclusion:It is still essential to discuss the threshold's characteristics and establish the methods framework complementing both demand and supply side for Chinese health insurance,and to standardize and normalize the measurement methods,as well as to set up multi-level thresholds according to the preferences of the population,the severity of the disease,and so on,in order to take into account both economy and equity.

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