Objective To explore the clinical effect and safety of 4K high-definition laparoscopic-assisted transabdominal preperitoneal repair in the treatment of elderly inguinal hernia.Methods A retrospective analysis was conducted on the medical records of 92 elderly patients with inguinal hernia.They were divided into control group(n=42)and study group(n=50)according the treatment plan.Conventional laparoscopic preperitoneal repair was applied in the control group.4K high-definition laparoscopic-assisted transabdominal preperitoneal repair was used in the study group.Operation related indexes,postoperative pain(visual analogue scale[VAS]),blood gas indexed(arterial partial pressure of carbon dioxide[PaCO2],arterial partial pressure of oxygen[PaO2],and pH value),serum inflammatory factor levels(C-reactive protein[CRP]and interleukin-6[IL-6])were compared between the two groups.The incidence of postoperative complications was recorded.Results The study group had longer operation time and shorter exercise time leaving bed and hospitalization time than the control group(P<0.05).There was no statistically significant difference in the PaCO2,PaO2 or pH value between the two groups before and 48 h after operation(P>0.05).The VAS scores of the study group at 24 h,48 h and 72 h after operation were lower than those of the control group(P<0.05).The levels of CRP and IL-6 at 48 h after operation were decreased in both groups,and the parameters in the study group were significantly lower than those in the control group(P<0.05).There was no statistically significant difference in the incidence of postoperative complications or recurrence rate between the two groups(P>0.05).Conclusion 4K high-definition laparoscopic-assisted transabdominal preperitoneal repair has more advantages in promoting postoperative recovery and reducing postoperative pain in elderly patients with inguinal hernia.Compared with conventional laparoscopic preperitoneal repair,its operation time is slightly longer.