Central nervous system（CNS） disorders are characterized by complex pathological mechanisms and the presence of the blood-brain barrier（BBB）， which significantly limits the effectiveness of drug therapy. Traditional drug delivery modes include oral administration， intravenous injection and transdermal delivery， which have certain advantages， but it is difficult for the drugs to effectively cross the BBB. Therefore， it is crucial to find drug delivery modes that can efficiently traverse the BBB. Nasal drug delivery， as a non-invasive method， can realize the targeted delivery of drugs to the CNS via three pathways， including olfactory neurons， trigeminal neurons and blood circulation， and shows a broad application prospect in the treatment of CNS diseases. Numerous studies have further confirmed that nasal drug delivery combined with novel drug delivery systems such as lipid nanocarriers， nanoparticles， nanoemulsions and composite in situ gels can effectively load the active components of traditional Chinese medicine（TCM）， and significantly increase drug concentration in the brain， which provides new strategies for the treatment of CNS diseases. In this paper， the current status of drug delivery for CNS diseases was systematically sorted out， the characteristics of nasal drug delivery were discussed in depth， and the research progress of passive targeting， active targeting， and "guiding the meridian" drug delivery strategies for the nasal-to-brain transport of TCM active components was summarized and analyzed， which was aimed to provide references and insights for the development of drugs for CNS diseases and the application of TCM in nasal-to-brain delivery.

Central nervous system（CNS） disorders are characterized by complex pathological mechanisms and the presence of the blood-brain barrier（BBB）， which significantly limits the effectiveness of drug therapy. Traditional drug delivery modes include oral administration， intravenous injection and transdermal delivery， which have certain advantages， but it is difficult for the drugs to effectively cross the BBB. Therefore， it is crucial to find drug delivery modes that can efficiently traverse the BBB. Nasal drug delivery， as a non-invasive method， can realize the targeted delivery of drugs to the CNS via three pathways， including olfactory neurons， trigeminal neurons and blood circulation， and shows a broad application prospect in the treatment of CNS diseases. Numerous studies have further confirmed that nasal drug delivery combined with novel drug delivery systems such as lipid nanocarriers， nanoparticles， nanoemulsions and composite in situ gels can effectively load the active components of traditional Chinese medicine（TCM）， and significantly increase drug concentration in the brain， which provides new strategies for the treatment of CNS diseases. In this paper， the current status of drug delivery for CNS diseases was systematically sorted out， the characteristics of nasal drug delivery were discussed in depth， and the research progress of passive targeting， active targeting， and "guiding the meridian" drug delivery strategies for the nasal-to-brain transport of TCM active components was summarized and analyzed， which was aimed to provide references and insights for the development of drugs for CNS diseases and the application of TCM in nasal-to-brain delivery.

It analyzes the development achievements of the construction of the basic medical security system and the key issues of its high-quality development in China,and puts forward the countermeasures of promoting the high-quality development of the basic medical security system.In recent years,China's basic medical security system has made remarkable development achievements,but it is still facing a series of problems in the areas of participation,financing,treatment guarantee security and fund supervision.The implementation of accurate participation and expansion,the improvement of the financing mechanism,and the promotion of synergistic development and governance of medical care,medical insurance and pharmaceuticals are the keys to meeting the residents'growing health needs and promoting the high-quality development of China's basic medical security system.

It analyzes the development achievements of the construction of the basic medical security system and the key issues of its high-quality development in China,and puts forward the countermeasures of promoting the high-quality development of the basic medical security system.In recent years,China's basic medical security system has made remarkable development achievements,but it is still facing a series of problems in the areas of participation,financing,treatment guarantee security and fund supervision.The implementation of accurate participation and expansion,the improvement of the financing mechanism,and the promotion of synergistic development and governance of medical care,medical insurance and pharmaceuticals are the keys to meeting the residents'growing health needs and promoting the high-quality development of China's basic medical security system.

It analyzes the development achievements of the construction of the basic medical security system and the key issues of its high-quality development in China,and puts forward the countermeasures of promoting the high-quality development of the basic medical security system.In recent years,China's basic medical security system has made remarkable development achievements,but it is still facing a series of problems in the areas of participation,financing,treatment guarantee security and fund supervision.The implementation of accurate participation and expansion,the improvement of the financing mechanism,and the promotion of synergistic development and governance of medical care,medical insurance and pharmaceuticals are the keys to meeting the residents'growing health needs and promoting the high-quality development of China's basic medical security system.

It analyzes the development achievements of the construction of the basic medical security system and the key issues of its high-quality development in China,and puts forward the countermeasures of promoting the high-quality development of the basic medical security system.In recent years,China's basic medical security system has made remarkable development achievements,but it is still facing a series of problems in the areas of participation,financing,treatment guarantee security and fund supervision.The implementation of accurate participation and expansion,the improvement of the financing mechanism,and the promotion of synergistic development and governance of medical care,medical insurance and pharmaceuticals are the keys to meeting the residents'growing health needs and promoting the high-quality development of China's basic medical security system.

It analyzes the development achievements of the construction of the basic medical security system and the key issues of its high-quality development in China,and puts forward the countermeasures of promoting the high-quality development of the basic medical security system.In recent years,China's basic medical security system has made remarkable development achievements,but it is still facing a series of problems in the areas of participation,financing,treatment guarantee security and fund supervision.The implementation of accurate participation and expansion,the improvement of the financing mechanism,and the promotion of synergistic development and governance of medical care,medical insurance and pharmaceuticals are the keys to meeting the residents'growing health needs and promoting the high-quality development of China's basic medical security system.

It analyzes the development achievements of the construction of the basic medical security system and the key issues of its high-quality development in China,and puts forward the countermeasures of promoting the high-quality development of the basic medical security system.In recent years,China's basic medical security system has made remarkable development achievements,but it is still facing a series of problems in the areas of participation,financing,treatment guarantee security and fund supervision.The implementation of accurate participation and expansion,the improvement of the financing mechanism,and the promotion of synergistic development and governance of medical care,medical insurance and pharmaceuticals are the keys to meeting the residents'growing health needs and promoting the high-quality development of China's basic medical security system.

It analyzes the development achievements of the construction of the basic medical security system and the key issues of its high-quality development in China,and puts forward the countermeasures of promoting the high-quality development of the basic medical security system.In recent years,China's basic medical security system has made remarkable development achievements,but it is still facing a series of problems in the areas of participation,financing,treatment guarantee security and fund supervision.The implementation of accurate participation and expansion,the improvement of the financing mechanism,and the promotion of synergistic development and governance of medical care,medical insurance and pharmaceuticals are the keys to meeting the residents'growing health needs and promoting the high-quality development of China's basic medical security system.

It analyzes the development achievements of the construction of the basic medical security system and the key issues of its high-quality development in China,and puts forward the countermeasures of promoting the high-quality development of the basic medical security system.In recent years,China's basic medical security system has made remarkable development achievements,but it is still facing a series of problems in the areas of participation,financing,treatment guarantee security and fund supervision.The implementation of accurate participation and expansion,the improvement of the financing mechanism,and the promotion of synergistic development and governance of medical care,medical insurance and pharmaceuticals are the keys to meeting the residents'growing health needs and promoting the high-quality development of China's basic medical security system.