Objective To discuss the mediating role of psychological consistency in self-perceived burden and quality of life in patients receiving 125I seed implantation treatment.Methods By using convenient sampling method a questionnaire was conducted in 154 patients,who received 125I seed implantation in Zhejiang Provincial Cancer Hospital between September 2021 and April 2022,were selected as the study subjects,and SPSS 23.0 and AMOS 24.0 were used for data analysis.Results Psychological consistency was negatively correlated with self-perceived burden(r=-0.353,P＜0.01)and was positively correlated with quality of life(r=0.457,P＜0.01).Self-perceived burden was negatively correlated with quality of life(r=-0.604,P＜0.01).Structural equation testing proved that psychological consistency had certain partial mediating effect on self-perceived burden and quality of life,accounting for 20.7％of the total effect.Conclusion Psychological consistency can not only directly affect the quality of life of patients,but also indirectly affect the quality of life of patients as a mediating variable of self-perceived burden.

Objective To investigate the effect of comprehensive intervention led by nursing staffers on the drug compliance in patients with hepatitis B virus-related hepatocellular carcinoma (HCC) after receiving transcatheter arterial chemoembolization (TACE) treatment.Methods By using random sampling method,a total of 96 patients with hepatitis B virus-associated HCC,who had been treated with TACE and had taken nucleotide analogue drug for one month in the interventional department of a certain grade Ⅲ tumor hospital,were enrolled in this study.Under the premise of informed consent,comprehensive intervention,which was led by nursing staffers and was participated by both doctors and nurses,was conducted.Results After comprehensive intervention,the average score of drug compliance was (93.670±6.046) points,while the pre-intervention average score of drug compliance was (82.040±10.024) points,the difference between the two was statistically significant (P＜0.05).The ratio of patients who showed good drug compliance changed from pre-intervention 62.4％ to post-prevention 97.8％(P＜0.05).The post-prevention of patients,whose hepatitis B virus deoxyribonucleic acid (HBVDNA) level was within the normal range,was 45.16％,which was highcr than the pre-intervention ratio of 15.05％,the difference between the two was statistically significant (P＜0.05).Conclusion The comprehensive intervention led by nursing staffers can effectively improve the drug compliance in patients with hepatitis B virus-associated HCC after receiving TACE,and can reliably control serum HBVDNA level as well.