Objective:To investigate the diagnostic value of serum ferritin in intestinal failure-associated liver disease. Methods:Clinical data of adult patients with short bowel syndrome admitted to the Department of General Surgery of Jinling Hospital affiliated to Nanjing University from January 2019 to December 2022 were retrospectively analyzed to determine the correlation between serum ferritin and liver enzyme profiles by linear regression,to screen the potential risk factors of liver injury by multifactorial Logistic regression analysis,and to establish a prediction model for liver fibrosis. The area under the curve was also calculated to assess the accuracy of the model. Results:A total of 106 patients with short bowel syndrome were included,of whom 55 (51.9％) had elevated serum ferritin (SF). Linear regression analysis showed a positive correlation between serum ferritin and ALT (r=0.427,P<0.001),ALP (r=0.365,P<0.001),and γ-GT (r=0.423,P<0.001),and one-way Logistic regression analysis showed that the higher the level of serum ferritin,the more pronounced the difference was (SF>ULN) The one-way logistic regression analysis showed that the higher the serum ferritin level,the more significant the difference was[SF>ULN (upper limit of normal value of serum ferritin),P=0.033;SF>1.5×ULN,P=0.018;SF>2.5×ULN,P=0.006]. Multifactorial logistic regression analysis showed that PN dependence (OR=3.366,P=0.017) and serum ferritin>2.5 ULN (OR=3.292,P=0.014)were independent risk factors for intestinal failure-associated liver disease-liver fibrosis,and the receiver operating curve (ROC) of the subjects showed area under the curve of 74.8％,95％ CI:0.652～0.844. Conclusion:Serum ferritin can be used as a reliable clinical biomarker to help identify intestinal failure-associated liver disease.

Objective:To explore the safety and effectiveness of placing nasointestinal tubes under bedside electromagnetic navigation in elderly patients,and to investigate the factors related to successful nasointestinal tube placement.Method:A retrospective analysis was conducted on the records of all elderly patients undergoing nasointestinal tube placement under bedside electromagnetic navigation at General Hospital Of Eastern Theater Command from June 1,2021 to January 31,2024.Statistical analysis was performed on the relevant indicators of the placement tube and the factors related to successful placement.Result:A total of 163 elderly patients were included,with a total success rate of 87.7%,an average placement time of(18.5±18.9)min,an average inserted nasal intestinal tube length of(104.6±9.8)cm,and a placement-related complications rate of 1.8%.The factors related to successful placement include chronic disease as the main diagnosis(P=0.0196),preoperative placement of a gastric tube(P=0.0060),and preoperative use of prokinetic drugs(P=0.0268).Conclusion:Placing nasointestinal tubes under bedside electromagnetic navigation is an efficient and safe method for placing nasointestinal tubes in elderly patients.The success rate of placement in chronic patients is higher.Preoperative placement of a gastric tube and use of prokinetic drugs may help with tube placement.