Chest wall tumor(CWT) is a heterogeneous tumor involving multiple systems, including primary and secondary tumors. Chest wall tumors should first be classified according to their histological origin before distinguishing between benign and malignant. Except for a very few malignant tumors, surgical resection is the first choice for the treatment of chest wall tumors. However, chest wall tumors are different from other tumors in that resection of these tumors will compromise the integrity and stability of the chest wall, which makes it necessary before surgery to evaluate not only whether the tumor can be resected, but also the necessity and feasibility of postoperative chest wall reconstruction. With the progress of medical technology, the styles and methods of surgical treatment of chest wall tumors have also made marked advancements. This article aims to briefly review the changes and developments of surgical treatment of chest wall tumors in recent years, so as to provide a reference for clinical work.

Opioid-free anesthesia(OFA)is a multimodal analgesic strategy that combines multiple non-opioid drugs and/or techniques to obtain high-quality anesthesia.With the popularization of the concept of enhanced recovery after surgery(ERAS),OFA has become a common concern hot spot for perioperative phy-sicians.OFA is in line with the ERAS concept,and under multimodal anesthesia and pain management,it can reduce surgical stress,inflammation reaction and postoperative complications,significantly improve the prog-nosis of patients,promote postoperative rapid recovery and reduce the burden of medical and health resources.This article reviews the adverse reactions of opioids,OFA concept and indications,the clinical application of OFA in recent years,the existing controversies and problems to be solved.