Objective To investigate the characteristics of changes in blood uric acid(UA)and detection rate of hyperuricemia(HUA)among officers and soldiers during long-term maritime missions,as well as their related influencing factors.Methods A total of 100 servicemen were randomly selected from 240 officers and soldiers who will participate in a long-distance voyage mission.Their general information,including age,education level,administrative position,years of service on board,and department,was surveyed.Their annual data of physical examination were retrospectively analyzed and compared with the results of another 335 shore-based servicemen during the same period.On mission day 10(D10)and day 50(D50),the venous blood samples were collected from the participants to synchronously measure blood UA level and body composition indicators(body fat mass,BMI,fat percentage,fat mass,muscle mass,and muscle percentage).Additionally,on D50,Self-Rating Scale of Sleep(SRSS)and Symptom Checklist-90(SCL-90)were employed to survey their conditions.Seventy service members were randomly selected from the 100 participants to engage in aerobic exercise.The changes in UA level and detection rate of HUA among the mission personnel were analyzed,along with their influencing factors.Results The UA level and HUA detection rate in long-term navigation personnel during concurrent annual physical examinations were significantly lower than those in shore-based personnel(P<0.01).Compared to pre-voyage physical examination results,the UA level and HUA detection rate in long-term navigation personnel were significantly increased from mission day D10(P<0.001).Compared to the values at D10,the UA level and HUA detection rate at D50 showed significant decreases(P<0.05),and then essentially returned to pre-mission examination levels(P>0.05).Aged<32 years was an independent risk factor for new-onset HUA at mission D10(P<0.05).<32 years old and aerobic exercise during the voyage were independent influencing factors for HUA outcome(P<0.05).Conclusion Serum UA level and HUA detection rate among officers and soldiers participating in long-term maritime missions are relatively low before departure,but in significant increases during the early stages of the mission,particularly among those aged<32 years.Scientific aerobic exercise during the mission period helps reduce UA level and HUA detection rate,playing a crucial role in guaranteeing physical and mental health.

Objective This study aimed to explore the risk factors of postoperative hypokalemia in patients with oral cancer and to provide a basis for preventing and controlling postoperative hypokalemia.Methods We included 366 pa-tients undergoing oral cancer surgery in the Department of Head and Neck Oncology,West China Hospital of Stomatolo-gy,Sichuan University from January 2022 to August 2022.Univariate and multivariate analyses were used to determine the risk factors of postoperative hypokalemia.The receiver operation characteristic(ROC)curve was used to quantify the effectiveness of the factors.A nomogram of the risk factors for postoperative hypokalemia in oral cancer patients was de-veloped and validated.Results A total of 224 patients(61.20％)had postoperative hypokalemia,the lowest serum po-tassium level(3.50±0.35)mmol/L on the 4th day after surgery,and the highest incidence of hypokalemia(54.68％).Vari-ables with P＜0.05 in the univariate analysis were quantified by ROC curve followed by multivariate logistic regression analysis.Results showed an independent correlation with postoperative hypokalemia as follows:preoperative se-rum potassium＜3.87 mmol/L(P=0.008),preoperative se-rum calcium＜2.31 mmol/L(P=0.033),preoperative PNI＜49.16(P=0.032),postoperative drainage volume＞264.25 mL(P=0.002).The above variables were constructed into a postoperative hypokalemia risk nomogram and verified,and a good degree of fit was found.Conclusion The indepen-dent risk factors for postoperative hypokalemia in patients with oral cancer were as follows:preoperative serum potassi-um＜3.87 mmol/L,preoperative serum calcium＜2.31 mmol/L,preoperative PNI＜49.16,and postoperative drainage vol-ume＞264.25 mL.Clinical attention should be paid to managing the above high-risk patients.Preventive potassium sup-plementation should be performed as soon as possible to reduce hypokalemia occurrence.