Objective: Metabloc Syndrome has been implicated in several diseases including heart attack and stroke. At the 29th International Stroke Conference, it was emphasized that metabolic syndrome may almost double the risk of stroke and steps should be done towards its prevention. We, therefore, investigated the prevalence of metabolic syndrome among Filipino stroke patients and compared two definitions of metabolic syndrome: the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) and the International Diabetes Federation consensus (IDF).Methodology: This is a prevalence study involving stroke patients admitted at our institution from November 2005 to November 2006 using condition-specific cut points for metabolic syndrome as defined by NCEP-ATP III and IDF consensus. Counts, frequencies and means were used. Differences inicharacteristics were tested for statistical significance using chi square test and Mann-Whitney (I test.Results: Metabolic syndrome using the IDF consensus was fulfilled by 72 (40.7 percent) patients, all of which are included in the 108 patients (61 percent) that fulfilled the NCEP-ATP III criteria. Of the 177 patients, 40.7 percent fulfilled both criteria. There was concordance between the two definitions (Cohen kappa coefficient - 0.6092; p < 0.0001)Conclusion: There is higher prevalence estimate of metabolic syndrome in Filipino stroke patients when using the NCEP-ATP III criteria compared to the IDF criteria. There is, however, good concordance between the two definitions.
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OBJECTIVES: To determine the prevalence, risk factors, etiology, location, and outcome of non-traumatic intracerebral hemorrhage (ICH) in young Filipino patients. To identify factors associated with poor outcome and mortality
METHODOLOGY: Review of charts of patients age /- 45 years admitted for acute non-traumatic intracerebral hemorrhage with neuroimaging evidence of symptomatic ICH was done. Data regarding risk factors, location, etiology and outcome were analyzed using SPSS 9.01 for Windows and Epi 6 for univariate and multiple regression analysis
RESULTS: Seventy subjects were included. 66 percent were males and 34 percent were females. The mean age of the subjects was 37 years old. Prevalence of non-traumatic ICH among stroke in young adults is 17 percent. The most frequent risk factors were hypertension, smoking, alcohol use, and family history of CVD. The common locations in order were basal ganglia/internal capsule (44 percent), thalamus (22 percent), lobar, and brainstem. The common causes of ICH were hypertension (46 percent), vascular malformations (16 percent) and hematologic/coagulation disorders (13 percent). Arteriography was done in 33 percent of cases. Overall in-hospital mortality rate was 8.5 percent in the acute stage of ICH. Factors independently associated with poor outcome and mortality on multivariate regression analysis were posterior circulation (p=0.005), presence of intraventricular extension (p=0.002), ICH volume 30 cc (p= 0.011), and smoking history (p=0.021)
CONCLUSION: Non-traumatic intracerebral hemorrhage in young Filipino adults has a heterogenous etiology. Non-traumatic ICH occurred in 17 percent of young stroke patients. Posterior circulation involvement, presence of intraventricular extension, ICH volume of 30cc and smoking history were significant factors associated with poor outcome.

Human ; Male ; Female ; Adult ; Adolescent ; Smoking ; Cerebral Hemorrhage ; Stroke ; Cerebral Hemorrhage, Traumatic ; Hypertension ; Brain Stem ; Vascular Malformations