Objective To compare the efficacy and safety of great saphenous vein(GSV)trunk closure combined with local ablation and local sclerotherapy for treating varicose veins of lower limb.Methods Totally 78 patients with unilateral varicose veins of lower limb were retrospectively enrolled and divided into GSV trunk closure combined with local ablation group(group A,n=36)and local sclerotherapy group(group B,n=42).The venous clinical severity score(VCSS),Aberdeen varicose vein questionnaire(AVVQ)score before and 6 months after treatment,as well as the incidence of adverse reactions within 6 months after treatment were compared between groups.Results Six months after treatment,the main trunk closure rate of GSV was 100%in both groups,while VCSS and AVVQ scores were significantly lower than those before treatment(all P＜0.05).No significant difference of VCSS nor AVVQ score before and after treatment was found between groups(all P＞0.05).The incidence of thrombosis,skin paresthesia and subcutaneous induration in group B were all higher than those in group A,while of residual varicose veins in group B was lower than that in group A(all P＜0.05).Conclusion Both GSV trunk closure combined with local ablation and local sclerotherapy could be used to effectively treat varicose veins of lower limb,and the former had fewer adverse reactions.

Objective To compare the efficacy and safety of great saphenous vein(GSV)trunk closure combined with local ablation and local sclerotherapy for treating varicose veins of lower limb.Methods Totally 78 patients with unilateral varicose veins of lower limb were retrospectively enrolled and divided into GSV trunk closure combined with local ablation group(group A,n=36)and local sclerotherapy group(group B,n=42).The venous clinical severity score(VCSS),Aberdeen varicose vein questionnaire(AVVQ)score before and 6 months after treatment,as well as the incidence of adverse reactions within 6 months after treatment were compared between groups.Results Six months after treatment,the main trunk closure rate of GSV was 100%in both groups,while VCSS and AVVQ scores were significantly lower than those before treatment(all P＜0.05).No significant difference of VCSS nor AVVQ score before and after treatment was found between groups(all P＞0.05).The incidence of thrombosis,skin paresthesia and subcutaneous induration in group B were all higher than those in group A,while of residual varicose veins in group B was lower than that in group A(all P＜0.05).Conclusion Both GSV trunk closure combined with local ablation and local sclerotherapy could be used to effectively treat varicose veins of lower limb,and the former had fewer adverse reactions.