In a completely edentulous patient who cannot have implant-retained overdentures due to medical history and economic circumstances, a suction-effective complete denture utilizing the closed-mouth impression technique is being used to secure high retention. In this case, both a conventional complete denture using the open-mouth impression technique and a suction-effective complete denture using the closed-mouth impression technique were fabricated for a single completely edentulous patient. The results demonstrated that both methods provided excellent outcomes in terms of function, esthetics, and patient satisfaction. Conventional complete dentures increase the area of denture-bearing pressure to ensure retention and stability, whereas suction-effective complete dentures achieve retention by sealing the entire border of the denture. Since there are characteristic differences in the clinical and laboratory procedures due to differences in the concept of denture fabrication, this was compared through this case report.

In a completely edentulous patient who cannot have implant-retained overdentures due to medical history and economic circumstances, a suction-effective complete denture utilizing the closed-mouth impression technique is being used to secure high retention. In this case, both a conventional complete denture using the open-mouth impression technique and a suction-effective complete denture using the closed-mouth impression technique were fabricated for a single completely edentulous patient. The results demonstrated that both methods provided excellent outcomes in terms of function, esthetics, and patient satisfaction. Conventional complete dentures increase the area of denture-bearing pressure to ensure retention and stability, whereas suction-effective complete dentures achieve retention by sealing the entire border of the denture. Since there are characteristic differences in the clinical and laboratory procedures due to differences in the concept of denture fabrication, this was compared through this case report.

In a completely edentulous patient who cannot have implant-retained overdentures due to medical history and economic circumstances, a suction-effective complete denture utilizing the closed-mouth impression technique is being used to secure high retention. In this case, both a conventional complete denture using the open-mouth impression technique and a suction-effective complete denture using the closed-mouth impression technique were fabricated for a single completely edentulous patient. The results demonstrated that both methods provided excellent outcomes in terms of function, esthetics, and patient satisfaction. Conventional complete dentures increase the area of denture-bearing pressure to ensure retention and stability, whereas suction-effective complete dentures achieve retention by sealing the entire border of the denture. Since there are characteristic differences in the clinical and laboratory procedures due to differences in the concept of denture fabrication, this was compared through this case report.

Background: s/Aims: The hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) is classified as the advanced stage (BCLC stage C) with extremely poor prognosis, and in current guidelines is recommended for systemic therapy. This study aimed to evaluate the surgical outcomes and long-term prognosis after hepatic resection (HR) for patients who have HCC combined with PVTT. Methods: We retrospectively analyzed 332 patients who underwent HR for HCC with PVTT at ten tertiary referral hospitals in South Korea. Results: The median overall and recurrence-free survival after HR were 32.4 and 8.6 months, while the 1-, 3-, and 5-year overall survival rates were 75%, 48%, and 39%, respectively. In multivariate analysis, tumor number, tumor size, AFP, PIVKA−II, neutrophil-to-lymphocyte ratio, and albumin–bilirubin (ALBI) grade were significant prognostic factors. The risk scoring was developed using these seven factors–tumor, inflammation and hepatic function (TIF), to predict patient prognosis. The prognosis of the patients was well stratified according to the scores (log-rank test, p < 0.001). Conclusions HR for patients who have HCC combined with PVTT provided favorable survival outcomes. The risk scoring was useful in predicting prognosis, and determining the appropriate treatment strategy for those patients who have HCC with PVTT.

Background: and Purpose Unlike other immune-mediated neuropathies, anti-myelin-associated glycoprotein (MAG) neuropathy is often refractory to immunotherapy. It is necessary to compare the relative efficacies of various immunotherapies and develop objective biomarkers in order to optimize its clinical management. Methods: This study recruited 91 patients with high anti-MAG antibody titers from 7 tertiary hospitals in South Korea. We analyzed the baseline characteristics, therapeutic outcomes, and nerve conduction study (NCS) findings of 68 patients and excluded 23 false positive cases. Results: The rate of positive responses to treatment was highest using zanubrutinib (50%) and rituximab (36.4%), followed by corticosteroids (16.7%), immunosuppressants (9.5%), intravenous immunoglobulin (5%), and plasma exchange (0%). Disability and weakness were significantly associated with multiple NCS parameters at the time of diagnosis, especially distal compound muscle action potential (CMAP) amplitudes. Moreover, the longitudinal trajectory of the average CMAP amplitudes paralleled the clinical courses, with a 16.2 percentile decrease as an optimal cutoff for predicting a clinical exacerbation (area under the receiver operating characteristic curve=0.792). Conclusions Our study supports the use of NCS as an objective marker for estimating disease burden and tracking clinical changes in patients with anti-MAG neuropathy. We have described the beneficial effects of rituximab and a new drug, zanubrutinib, compared with conventional immunotherapies.