1.Prevalence and genotype distribution of human papillomavirus among Korean males: Implications for vaccination strategies
Seon Beom JO ; Sun Tae AHN ; Jong Wook KIM ; Mi Mi OH ; Dong Soo LEE ; Yong-Hak SOHN ; Du Geon MOON
Investigative and Clinical Urology 2026;67(1):62-71
Purpose:
We aimed to investigate the prevalence and genotype distribution of human papillomavirus (HPV) among Korean males and explore implications for targeted vaccination strategies.
Materials and Methods:
A total of 44,065 males underwent HPV testing between March 2014 and February 2022 using the Anyplex™ II HPV 28 system, detecting 19 high-risk (HR) and 9 low-risk (LR) HPV types. Additionally, data from 507 male patients at local clinic (2017–2022) were analyzed to compare genotype prevalence between those with (WAT group) and without (WAT X group) genital warts.
Results:
Overall HPV positivity was 59.1%. HPV 6 (33.3%) and HPV 11 (11.0%) were the most prevalent LR genotypes, while HPV 16 (5.2%) dominated HR infection. Multiple HPV genotype co-infection occurred in 49.3% of positive cases, with 11.3% involving multiple HR types. Younger males (teens, 20s) exhibited higher HR-HPV positivity, although total HPV positivity peaked in the 40s (60.1%). Non–9-valent HR genotypes (HPV 53, 51, 39, 66) accounted for 27.6%–35.0% of infections annually. At local clinic, HPV 43 was significantly associated with genital warts (p=0.017).
Conclusions
These data support including males in national HPV vaccination strategies using the current 9-valent vaccine and underscore the need for ongoing genotype surveillance to monitor non‑vaccine high‑risk types and inform public health policy, and support inclusion of males in national HPV vaccination strategies using the current 9‑valent vaccine.
2.The diagnostic accuracy of depth prediction for lipomas by preoperative imaging with distribution according to anatomical site in Korea: a retrospective analysis
Archives of Craniofacial Surgery 2025;26(1):13-18
Background:
Lipomas are common benign connective-tissue tumors that usually present as slow-growing, painless, subcutaneous masses. Deeper variants, such as intramuscular, intermuscular, and submuscular lipomas, are larger and rarer. Accurate preoperative depth determination is crucial for planning appropriate surgical resection.
Methods:
We retrospectively reviewed 190 lipoma cases treated at a single medical center from January 2013 to August 2023. The accuracy of preoperative imaging techniques–ultrasonography (USG), computed tomography (CT), and magnetic resonance imaging (MRI)–in predicting lipoma depth was assessed.
Results:
USG, CT, and MRI showed accuracies of 72.5%, 56.5%, and 79.3%, respectively, with MRI showing the highest predictive accuracy. The trunk was the most common site for lipomas (49.5%), followed by the upper (20.5%) and lower extremities (13.2%). USG was more accurate for lipomas in the lower extremities and neck, whereas CT was less accurate for lipomas in the trunk.
Conclusion
MRI is preferable for the preoperative depth assessment of lipomas, especially those located in the trunk. Accurate imaging is essential for guiding surgical planning and avoiding complications. Further studies with larger sample sizes are required to validate our findings.
3.The diagnostic accuracy of depth prediction for lipomas by preoperative imaging with distribution according to anatomical site in Korea: a retrospective analysis
Archives of Craniofacial Surgery 2025;26(1):13-18
Background:
Lipomas are common benign connective-tissue tumors that usually present as slow-growing, painless, subcutaneous masses. Deeper variants, such as intramuscular, intermuscular, and submuscular lipomas, are larger and rarer. Accurate preoperative depth determination is crucial for planning appropriate surgical resection.
Methods:
We retrospectively reviewed 190 lipoma cases treated at a single medical center from January 2013 to August 2023. The accuracy of preoperative imaging techniques–ultrasonography (USG), computed tomography (CT), and magnetic resonance imaging (MRI)–in predicting lipoma depth was assessed.
Results:
USG, CT, and MRI showed accuracies of 72.5%, 56.5%, and 79.3%, respectively, with MRI showing the highest predictive accuracy. The trunk was the most common site for lipomas (49.5%), followed by the upper (20.5%) and lower extremities (13.2%). USG was more accurate for lipomas in the lower extremities and neck, whereas CT was less accurate for lipomas in the trunk.
Conclusion
MRI is preferable for the preoperative depth assessment of lipomas, especially those located in the trunk. Accurate imaging is essential for guiding surgical planning and avoiding complications. Further studies with larger sample sizes are required to validate our findings.
4.The diagnostic accuracy of depth prediction for lipomas by preoperative imaging with distribution according to anatomical site in Korea: a retrospective analysis
Archives of Craniofacial Surgery 2025;26(1):13-18
Background:
Lipomas are common benign connective-tissue tumors that usually present as slow-growing, painless, subcutaneous masses. Deeper variants, such as intramuscular, intermuscular, and submuscular lipomas, are larger and rarer. Accurate preoperative depth determination is crucial for planning appropriate surgical resection.
Methods:
We retrospectively reviewed 190 lipoma cases treated at a single medical center from January 2013 to August 2023. The accuracy of preoperative imaging techniques–ultrasonography (USG), computed tomography (CT), and magnetic resonance imaging (MRI)–in predicting lipoma depth was assessed.
Results:
USG, CT, and MRI showed accuracies of 72.5%, 56.5%, and 79.3%, respectively, with MRI showing the highest predictive accuracy. The trunk was the most common site for lipomas (49.5%), followed by the upper (20.5%) and lower extremities (13.2%). USG was more accurate for lipomas in the lower extremities and neck, whereas CT was less accurate for lipomas in the trunk.
Conclusion
MRI is preferable for the preoperative depth assessment of lipomas, especially those located in the trunk. Accurate imaging is essential for guiding surgical planning and avoiding complications. Further studies with larger sample sizes are required to validate our findings.
5.Scalp Bacterial Profile and Antibiotics Susceptibility Pattern in Patients With Primary Cicatricial Alopecia
Geon-Jong LEE ; So-Yeon KIM ; Thi Quynh TRANG TRAN ; Jaehyeon LEE ; Kyung-Hwa NAM ; Seok-Kweon YUN ; Jin PARK
Annals of Dermatology 2025;37(4):241-249
Background:
Primary cicatricial alopecia (PCA) is a group of disorders causing irreversible hair loss because of hair follicle destruction. Although bacterial colonization is suspected to contribute to PCA pathogenesis, its role remains unclear.
Objective:
To investigate bacterial colonization patterns and antibiotic susceptibility profiles in patients with PCA compared to those with non-inflammatory scalp conditions.
Methods:
This retrospective study analyzed bacterial cultures from scalp swabs of 161 subjects (68 patients with PCA and 93 controls) at a tertiary hospital between June 2011 and December 2023. Bacterial species and antibiotic resistance rates were evaluated using subgroup analyses of neutrophilic PCA (NCA).
Results:
PCA cultures showed a higher prevalence of Staphylococcus aureus (24.3%) and S. lugdunensis (8.1%) than controls, where S. capitis (54.5%) was predominant. Gram-negative bacteria were more frequent in the PCA group (13.5%) than in the control group (9.9%), with Klebsiella spp.(10.9%) being the most prevalent. Resistance rates were significantly higher in PCA for benzylpenicillin, fusidic acid, erythromycin, clindamycin, oxacillin, and telithromycin (p<0.05). Methicillin-resistant S. aureus was identified in 15% of S. aureus isolates from NCA cases. Gram-negative bacteria in PCA also exhibited increased resistance to ampicillin and ampicillin/sulbactam.
Conclusion
PCA exhibits distinct bacterial colonization and elevated antibiotic resistance, particularly in the neutrophilic subtypes. Bacterial culture and susceptibility testing are essential for targeted therapies in clinical practice. Further multicenter microbiome analyses with mechanistic studies are needed to elucidate bacterial contributions to PCA pathogenesis.
6.Medication-related osteonecrosis of the jaw: an evidence-based 2025position statement from a Korean multidisciplinary task force
Jin-Woo KIM ; Sung-Hye KONG ; Jae-Young KIM ; Mi Kyung KWAK ; Jun-Young KIM ; Ji-Hyeon OH ; Hyung-Youl PARK ; BeomTaek KIM ; Young-Kyun LEE ; Jeong Joon HAN ; Moon-Young KIM ; Yong Jun CHOI ; Yong-Dae KWON ; Kwang-Sup SONG ; Beom-Jun KIM ; Sun-Jong KIM ; Seung-Hoon BAEK ; Dong Ock LEE ; Han Seok CHOI ; Ha Young KIM ; Tae-Geon KWON ;
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2025;51(6):333-353
With a rapidly aging population and increasing use of antiresorptive agents, medication-related osteonecrosis of the jaw (MRONJ) represents a growing clinical challenge worldwide. To address the need for tailored clinical guidance, a multidisciplinary task force was convened. Five Korean academic societies—the Korean Society for Bone and Mineral Research, the Korean Association of Oral and Maxillofacial Surgeons, the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons, the Korean Society of Osteoporosis, and the Korean Endocrine Society—collaborated to develop this position statement. The consensus was formulated through comprehensive reviews of literature, combined with three rounds of formal surveys to consolidate expert opinion on controversial topics. This position paper provides evidence-based clinical guidelines for the prevention, diagnosis, and management of MRONJ tailored to the Korean healthcare environment. The diagnostic criteria affirm the standard definition but add a provision for diagnosis based on clinical or radiographic evidence of necrotic bone, even if the traditional 8-week timeframe has not been met. The committee advocates for retaining Stage 0 in the staging system to emphasize early detection and preventive intervention. Key recommendations include prescriptive, drug-specific guidelines for prophylactic drug holidays (e.g., a 2-month pause for oral bisphosphonates; timing surgery 3-4 months after the last denosumab injection) to minimize MRONJ risk from dental procedures. This statement also provides a clear framework for therapeutic drug holidays in established MRONJ, carefully balancing the need for jaw healing against systemic fracture risk. For treatment, this statement advocates for early and active surgical intervention across all MRONJ stages, supported by evidence of superior long-term outcomes compared to conservative management.This position statement offers a unique, evidence-based Korean clinical practice guideline for managing MRONJ. It is intended to standardize care, reduce clinical confusion, and ultimately improve patient outcomes by providing a clear framework for decision-making.
7.Medication-Related Osteonecrosis of the Jaw: An Evidence-Based 2025 Position Statement from a Korean Multidisciplinary Task Force
Jin-Woo KIM ; Sung-Hye KONG ; Jae-Young KIM ; Mi Kyung KWAK ; Jun-Young KIM ; Ji-Hyeon OH ; Hyung-Youl PARK ; BeomTaek KIM ; Young-Kyun LEE ; Jeong Joon HAN ; Moon-Young KIM ; Yong Jun CHOI ; Yong-Dae KWON ; Kwang-Sup SONG ; Beom-Jun KIM ; Sun-Jong KIM ; Seung-Hoon BAEK ; Dong Ock LEE ; Han Seok CHOI ; Ha Young KIM ; Tae-Geon KWON
Endocrinology and Metabolism 2025;40(6):787-810
With a rapidly aging population and increasing use of antiresorptive agents, medication-related osteonecrosis of the jaw (MRONJ) represents a growing clinical challenge worldwide. To address the need for tailored clinical guidance, a multidisciplinary task force was convened. Five Korean academic societies—the Korean Society for Bone and Mineral Research, the Korean Association of Oral and Maxillofacial Surgeons, the Korean Society of Maxillofacial Plastic and Reconstructive Surgeons, the Korean Osteoporosis Society, and the Korean Endocrine Society—collaborated to develop this position statement. The consensus was formulated through comprehensive reviews of literature, combined with three rounds of formal surveys to consolidate expert opinion on controversial topics. This position paper provides evidence-based clinical guidelines for the prevention, diagnosis, and management of MRONJ tailored to the Korean healthcare environment. The diagnostic criteria affirm the standard definition but add a provision for diagnosis based on clinical or radiographic evidence of necrotic bone, even if the traditional 8-week timeframe has not been met. The committee advocates for retaining stage 0 in the staging system to emphasize early detection and preventive intervention. Key recommendations include prescriptive, drug-specific guidelines for prophylactic drug holidays (e.g., a 2-month pause for oral bisphosphonates; timing surgery 3 to 4 months after the last denosumab injection) to minimize MRONJ risk from dental procedures. This statement also provides a clear framework for therapeutic drug holidays in established MRONJ, carefully balancing the need for jaw healing against systemic fracture risk. For treatment, this statement advocates for early and active surgical intervention across all MRONJ stages, supported by evidence of superior long-term outcomes compared to conservative management. This position statement offers a unique, evidence-based Korean clinical practice guideline for managing MRONJ. It is intended to standardize care, reduce clinical confusion, and ultimately improve patient outcomes by providing a clear framework for decision-making.
8.A Study on the Behavior, Problems, and Countermeasures of Cosmetic General Practitioners Impersonating Dermatologists in Korea
Kyung-Hwa NAM ; Geon-Jong LEE ; Tae-Jong KANG ; Hyun-Ji RYU ; Jin PARK ; Seok-Kweon YUN
Korean Journal of Dermatology 2024;62(9):503-509
Background:
The number of general cosmetic practitioners impersonating dermatologists in Korea has increased, leading to serious harm that is significant enough to attract the attention of health authorities, which dermatologists are deeply concerned about.
Objective:
We conducted a survey targeting dermatologists to gather their opinions on the behavior, problems, and countermeasures of general cosmetic practitioners disguising themselves as dermatologists.
Methods:
A total of 280 dermatologists completed the survey between January and February 2024. The questions covered demographic characteristics, experiences of cosmetic general practitioners falsely introduced themselves as dermatologists, complications experienced by patients who received treatment after being mistaken for a dermatologist, the seriousness of the problem for cosmetic general practitioners impersonating dermatologists, and the relationship between the shortage of essential medical personnel and the phenomenon of cosmetic general practitioners disguising themselves as dermatologists.
Results:
Despite cases in which cosmetic general practitioners impersonate dermatologists, most dermatologists have not responded appropriately in many instances. Dermatologists have reported many cases of complications after receiving dermatological treatment from such cosmetic general practitioners. Most dermatologists are concerned about the serious problems of general cosmetic practitioners, disguising themselves as dermatologists and anticipating many adverse effects.
Conclusion
We believe that we need to pool our wisdom to solve these problems and expect that this study will provide valuable basic data for solving these problems in the dermatology and medical environments of Korea.
9.A Study on the Behavior, Problems, and Countermeasures of Cosmetic General Practitioners Impersonating Dermatologists in Korea
Kyung-Hwa NAM ; Geon-Jong LEE ; Tae-Jong KANG ; Hyun-Ji RYU ; Jin PARK ; Seok-Kweon YUN
Korean Journal of Dermatology 2024;62(9):503-509
Background:
The number of general cosmetic practitioners impersonating dermatologists in Korea has increased, leading to serious harm that is significant enough to attract the attention of health authorities, which dermatologists are deeply concerned about.
Objective:
We conducted a survey targeting dermatologists to gather their opinions on the behavior, problems, and countermeasures of general cosmetic practitioners disguising themselves as dermatologists.
Methods:
A total of 280 dermatologists completed the survey between January and February 2024. The questions covered demographic characteristics, experiences of cosmetic general practitioners falsely introduced themselves as dermatologists, complications experienced by patients who received treatment after being mistaken for a dermatologist, the seriousness of the problem for cosmetic general practitioners impersonating dermatologists, and the relationship between the shortage of essential medical personnel and the phenomenon of cosmetic general practitioners disguising themselves as dermatologists.
Results:
Despite cases in which cosmetic general practitioners impersonate dermatologists, most dermatologists have not responded appropriately in many instances. Dermatologists have reported many cases of complications after receiving dermatological treatment from such cosmetic general practitioners. Most dermatologists are concerned about the serious problems of general cosmetic practitioners, disguising themselves as dermatologists and anticipating many adverse effects.
Conclusion
We believe that we need to pool our wisdom to solve these problems and expect that this study will provide valuable basic data for solving these problems in the dermatology and medical environments of Korea.
10.A Study on the Behavior, Problems, and Countermeasures of Cosmetic General Practitioners Impersonating Dermatologists in Korea
Kyung-Hwa NAM ; Geon-Jong LEE ; Tae-Jong KANG ; Hyun-Ji RYU ; Jin PARK ; Seok-Kweon YUN
Korean Journal of Dermatology 2024;62(9):503-509
Background:
The number of general cosmetic practitioners impersonating dermatologists in Korea has increased, leading to serious harm that is significant enough to attract the attention of health authorities, which dermatologists are deeply concerned about.
Objective:
We conducted a survey targeting dermatologists to gather their opinions on the behavior, problems, and countermeasures of general cosmetic practitioners disguising themselves as dermatologists.
Methods:
A total of 280 dermatologists completed the survey between January and February 2024. The questions covered demographic characteristics, experiences of cosmetic general practitioners falsely introduced themselves as dermatologists, complications experienced by patients who received treatment after being mistaken for a dermatologist, the seriousness of the problem for cosmetic general practitioners impersonating dermatologists, and the relationship between the shortage of essential medical personnel and the phenomenon of cosmetic general practitioners disguising themselves as dermatologists.
Results:
Despite cases in which cosmetic general practitioners impersonate dermatologists, most dermatologists have not responded appropriately in many instances. Dermatologists have reported many cases of complications after receiving dermatological treatment from such cosmetic general practitioners. Most dermatologists are concerned about the serious problems of general cosmetic practitioners, disguising themselves as dermatologists and anticipating many adverse effects.
Conclusion
We believe that we need to pool our wisdom to solve these problems and expect that this study will provide valuable basic data for solving these problems in the dermatology and medical environments of Korea.

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