2.Hysteroscopic adhesiolysis and fertility outcomes of intrauterine adhesions due to endometrial tuberculosis.
Jianfa JIANG ; Dabao XU ; Yimin YANG
Journal of Central South University(Medical Sciences) 2025;50(1):52-60
OBJECTIVES:
Endometrial tuberculosis, which commonly affects women of reproductive age, is a significant cause of intrauterine adhesions (IUA), potentially leading to hypomenorrhea, amenorrhea, and infertility. Hysteroscopic adhesiolysis is the primary treatment for IUA; however, studies specifically addressing its efficacy in tuberculosis-induced IUA remain scarce. This study aims to evaluate the therapeutic outcomes of hysteroscopic adhesiolysis for IUA caused by endometrial tuberculosis.
METHODS:
This retrospective cohort study included patients diagnosed with tuberculosis-induced IUA who underwent hysteroscopic adhesiolysis at the Third Xiangya Hospital of Central South University between May 2014 and October 2022. Clinical data including age, medical history, adhesion severity, surgical treatment, and reproductive outcomes were analyzed.
RESULTS:
Among 39 patients identified, 2 were lost to follow-up. A total of 37 patients were included, with a follow-up duration ranging from 6 months to 9 years. Hypomenorrhea was reported in 24 (64.9%) patients, secondary amenorrhea in 10 (27.0%) patients, and normal menstruation in 3 (8.1%) patients. Most patients presented with primary infertility (59.5%), and only 2 (5.4%) had secondary infertility. The median American Fertility Society (AFS) score at initial assessment was 10 (range, 8-12); 8 (21.6%) patients had moderate IUA, and 29 (78.4%) had severe IUA. A total of 86 surgical procedures were performed across 37 patients, with 27 patients undergoing 2 or more surgeries. Postoperatively, 25 (67.6%) patients achieved normalization of the uterine cavity, while 12 (32.4%) still had a reduced cavity. Only 7 (18.9%) patients had a grossly normal endometrium at the final surgery, all of whom had moderate adhesions at the initial procedure. Menstrual flow returned to normal in 12 (32.4%) patients, while 25 (67.6%) continued to experience hypomenorrhea. Of 29 patients who attempted in vitro fertilization and embryo transfer (IVF-ET), only 6 (20.7%) conceived. Among these, 4 (13.8%) delivered at term via cesarean section; one case was complicated by postpartum hemorrhage due to uterine atony and another by placental adhesion.
CONCLUSIONS
Endometrial tuberculosis can lead to severe IUA. Hysteroscopic adhesiolysis facilitates cavity restoration and improvement of menstrual conditions, but the overall reproductive outcomes remain suboptimal.
Humans
;
Female
;
Hysteroscopy/methods*
;
Tissue Adhesions/etiology*
;
Retrospective Studies
;
Adult
;
Uterine Diseases/etiology*
;
Infertility, Female/surgery*
;
Treatment Outcome
;
Tuberculosis, Female Genital/surgery*
;
Fertility
;
Pregnancy
3.Adolescent male genitalia dissatisfaction: a surgical perspective.
Nicola ZAMPIERI ; Ilaria DANDO ; Francesco Saverio CAMOGLIO
Asian Journal of Andrology 2022;24(2):176-179
Genital dissatisfaction is well known in female and adults. Less is known about male adolescents and their genital satisfaction. The aim of this study was to investigate and report the role of surgery in male adolescents to improve the evaluation of their genitalia. We considered all patients treated for external genital pathology in the period of adolescence. Inclusion and exclusion criteria were created. Patients underwent an evaluation test before and after surgery. During the study period, 137 patients were treated, and at the end of the study, 98 cases were considered for analysis. The most frequent pathologies were webbed penis and penile curvature. A postoperative score improvement was noted and patients with concealed penis and webbed penis showed a better postoperative outcome. Overweight was considered an important factor associated with a worse preoperative score. Evaluation of the external genitalia is important in adolescents, and it is an understudied problem. Overweight may be associated with a worse evaluation of one's genital and should be clinically considered to avoid related social problems in adulthood. Therefore, cosmetic genital surgery should be considered even in male adolescents.
Adolescent
;
Adult
;
Female
;
Genital Diseases, Male/surgery*
;
Genitalia
;
Humans
;
Male
;
Overweight
;
Penile Diseases
;
Penis/surgery*
4.Recent advances in minimally invasive surgery for gynecologic indications
Yeungnam University Journal of Medicine 2018;35(2):150-155
Recently, an increasing interest in less invasive surgery has led to the advent of laparoendoscopic single-site surgery (LESS) and natural orifice transluminal endoscopic surgery (NOTES). LESS and NOTES could be technically challenging, but available literature has demonstrated the feasibility and safety of LESS for benign gynecologic diseases. However, the evidence is not strong enough to recommend the use of LESS over that of conventional multiport laparoscopic surgery (MLS). As per the results of the most recently published meta-analysis, the majority of surgical outcomes are equivalent between LESS and MLS, except for the longer operative time in LESS for both adnexal surgery and hysterectomy. Although an increasing number of studies have reported on robotic LESS, NOTES, and LESS for gynecologic malignancy, definite conclusions have not been drawn owing to the lack of sufficient information.
Female
;
Genital Diseases, Female
;
Hysterectomy
;
Laparoscopy
;
Minimally Invasive Surgical Procedures
;
Natural Orifice Endoscopic Surgery
;
Operative Time
5.Effects of electroacupuncture on postoperative functional recovery in patients with gynaecological laparoscopic surgery.
He ZHANG ; Lan WANG ; Min ZHANG ; Xiao-Hui WU ; Yin LI ; Zhao-Wei ZHANG ; Wei-Dong SHEN
Chinese Acupuncture & Moxibustion 2014;34(3):273-278
OBJECTIVETo evaluate electroacupuncture on the efficacy and the safety of gastric and systemic functional recovery in patients with carbon dioxide pneumoperitoneum undergoing gynaecological laparoscopic surgery.
METHODSSixty patients undergoing gynaecological laparoscopic surgery were randomly divided into a regular anesthesia group (group A) and a combination electroacupuncture anesthesia group (group B), 30 cases in each group. The group A were treated with regular general anesthesia, and on the basis of general anesthesia, the group B were treated with electroacupuncture at bilateral Zusanli (ST 36) and Liangqiu (ST 34) by continuous wave and a frequency of 2 Hz 30 minutes before the surgery until the end of the operation. Sedation scale by Ramsay, nausea, vomiting and mental state scores of postoperative were evaluated and compared between the two groups.
RESULTSCompared with the group A, the sedation scale (1.19 +/- 0.56 vs 1.96 +/- 0.90), nausea score (0.59 +/- 0.80 vs 1.81 +/- 0.88), vomiting score (0.48 +/- 0.94 vs 1.89 +/- 0.93) and mental state score (0.96 +/- 0.73 vs 1.69 +/- 0.75) were all decreased significantly in the group B (all P < 0.01).
CONCLUSIONCombination electroacupuncture anesthesia can relieve postoperative irritable, nausea and vomiting, improve mental state after the operation and promote the gastric and systemic functional recovery. It is a good method for the adjustment of carbon dioxide pneumoperitoneum during laparoscopic surgery.
Adult ; Electroacupuncture ; Female ; Genital Diseases, Female ; surgery ; Gynecologic Surgical Procedures ; adverse effects ; Humans ; Laparoscopy ; adverse effects ; Middle Aged ; Postoperative Complications ; physiopathology ; therapy ; Postoperative Period ; Recovery of Function ; Young Adult
6.Müllerian duct anomalies and their effect on the radiotherapeutic management of cervical cancer.
Madhup RASTOGI ; Swaroop REVANNASIDDAIAH ; Pragyat THAKUR ; Priyanka THAKUR ; Manish GUPTA ; Manoj K GUPTA ; Rajeev K SEAM
Chinese Journal of Cancer 2013;32(8):434-440
Radiotherapy plays a major role in the treatment of cervical cancer. A successful radiotherapy program integrates both external beam and brachytherapy components. The principles of radiotherapy are strongly based on the anatomy of the organ and patterns of local and nodal spread. However, in patients with distorted anatomy, several practical issues arise in the delivery of optimal radiotherapy, especially with brachytherapy. Müllerian duct anomalies result in congenital malformations of the female genital tract. Though being very commonly studied for their deleterious effects on fertility and pregnancy, they have not been recognized for their potential to interfere with the delivery of radiotherapy among patients with cervical cancer. Here, we discuss the management of cervical cancer among patients with Müllerian duct anomalies and review the very sparse amount of published literature on this topic.
Brachytherapy
;
Diagnostic Imaging
;
Female
;
Genital Diseases, Female
;
diagnosis
;
diagnostic imaging
;
pathology
;
Humans
;
Magnetic Resonance Imaging
;
Mullerian Ducts
;
abnormalities
;
diagnostic imaging
;
pathology
;
Radiography
;
Radiosurgery
;
Radiotherapy
;
methods
;
Uterine Cervical Neoplasms
;
radiotherapy
;
surgery
7.Coexistence of benign ovarian serous cystadenoma and tuberculosis in a young woman.
Flora Dorothy LOBO ; Meng Yee WONG
Singapore medical journal 2013;54(8):e154-7
Genital tuberculosis involving the ovary in a non-immunocompromised individual is rare. We report a case of coexisting ovarian serous cystadenoma and tuberculosis in a 29-year-old Indian woman. Clinical examination revealed the presence of an abdominal mass suspicious for ovarian neoplasm. Histopathological evaluation revealed ovarian neoplasm and concomitant tuberculosis. To the best of our knowledge, and after an extensive search of the literature, the coexistence of benign ovarian neoplasm and tuberculosis has not been previously documented.
Adult
;
Antitubercular Agents
;
therapeutic use
;
Cystadenoma, Serous
;
complications
;
surgery
;
Female
;
Humans
;
Ovarian Diseases
;
complications
;
drug therapy
;
surgery
;
Ovarian Neoplasms
;
complications
;
surgery
;
Tuberculosis, Female Genital
;
complications
;
drug therapy
;
surgery
8.Combination Effects of Capsicum Plaster at the Korean Hand Acupuncture Points K-D2 with Prophylactic Antiemetic on Postoperative Nausea and Vomiting after Gynecologic Laparoscopy.
Hyun Jung JUNG ; Sang Youn PARK
Journal of Korean Academy of Nursing 2013;43(2):215-224
PURPOSE: This study was done to evaluate the combination effects of capsicum plaster at the Korean hand acupuncture points K-D2 with prophylactic antiemetic on Postoperative Nausea and Vomiting (PONV). METHODS: An experimental research design (a randomized, a double-blinded, and a placebo-control procedure) was used. The participants were female patients undergoing gynecologic laparoscopy; the control group (n=34) received intravenous prophylactic ramosetron 0.3mg, while the experimental group (n=34) had Korean Hand Therapy additionally. In the experimental group, capsicum plaster was applied at K-D2 of both 2nd and 4th fingers by means of Korean Hand Therapy for a period of 30 minutes before the induction of anesthesia and removed 8 hours after the laparoscopy. RESULTS: The occurrence of nausea, nausea intensity and need for rescue with antiemetic in the experimental group was significantly less than in the control group 2 hours after surgery. CONCLUSION: Results of the study show capsicum plaster at K-D2 is an effective method for reducing PONV in spite of the low occurrence of PONV because of the prophylactic antiemetic medication.
Acupuncture Points
;
Adult
;
Anesthesia
;
Antiemetics/*therapeutic use
;
Asian Continental Ancestry Group
;
Capsaicin/therapeutic use
;
Capsicum/*chemistry
;
Double-Blind Method
;
Female
;
Fingers
;
Genital Diseases, Female/*surgery
;
Humans
;
Laparoscopy/adverse effects
;
Middle Aged
;
Postoperative Nausea and Vomiting/*drug therapy/etiology
;
Republic of Korea
;
Time Factors
;
Vomiting/*drug therapy/etiology
9.Influence of auricular point sticking on incidence of nausea and vomiting and analgesia effect after gynecological laparoscopy.
Li-Hong ZHANG ; Chun-Ling CAO ; Jing-Zhu LI ; Mei-Lun CHEN ; Ming-Shan WANG ; Chun-Yang DAI
Chinese Acupuncture & Moxibustion 2013;33(4):339-341
OBJECTIVETo observe the influence of auricular point sticking on incidence of nausea and vomiting and analgesia effect after gynecological laparoscopy, and provide evidence for clinical application of auricular point sticking.
METHODSOne hundred and twenty cases of selective gynecological laparoscopy under general anesthesia were randomly divided into an auricular point sticking group and a placebo group, 60 cases in each group. In the auricular point sticking group, the auricular point sticking with vaccaria seeds was applied at Shenmen (TF 4), Wei (CO 4) and Jiaogan (AH 6a) before the operation and 1, 5, 9, 23 h after the operation, which were pressed 5 min each point each time. The two ears were proceeded at the same time. In the placebo group, the same point selection, sticking paste was used as the auricular point sticking group, but no sticking or pressing with vaccaria seeds was adopted. The incidence of nausea and vomiting, the usage rate of tropisetron and morphine within 24 hours of the operation, as well as the score of visual analogue scale (VAS) and other adverse reactions at 2, 6, 10, 24 h after the operation were observed respectively.
RESULTSCompared with the placebo group, the incidence of nausea and vomiting [31.7% (19/60), 16.7% (10/60) vs 58.3% (35/60), 35.0% (21/60)], the usage rate of tropisetron [21.7% (13/60) vs 48.3% (29/60)] and morphine [18.3% (11/60) vs 38.3% (23/60)], the VAS scores at all different time points in the auricular point sticking group were all decreased (all P < 0.05), and no adverse reaction was observed.
CONCLUSIONThe auricular point sticking could significantly decrease the incidence of nausea and vomiting in patients of gynecological laparoscopy and has positive analgesic effect.
Acupuncture Analgesia ; Acupuncture Points ; Acupuncture, Ear ; Adult ; Female ; Genital Diseases, Female ; surgery ; Gynecology ; Humans ; Laparoscopy ; adverse effects ; Middle Aged ; Nausea ; etiology ; therapy ; Vomiting ; etiology ; therapy ; Young Adult
10.Effects of A-solution on Halitosis and Oral Status in Preoperative NPO Patients.
Journal of Korean Academy of Nursing 2012;42(3):405-413
PURPOSE: The aim of this study was to explore the effects of A-solution on halitosis and oral status in preoperative NPO patients. METHODS: A nonequivalent control group, non-synchronized pretest-posttest design was used in this study. The participants in this study were 66 patients who were admitted for gynecologic surgery. The experimental treatment was to give oral gargling with A-solution, blended essential oils and diluted with distilled water. To identify the experimental treatment effects, halitosis, salivary pH, and oral status were measured by a portable halitosis detector, visual analogue scale, Bromo Thymol Blue (BTB), Bromo Cresol Purple (BCP) test paper and oral assessment guide. Data were analyzed using chi2-test, t-test with PASW 18.0 version. RESULTS: Participants were homogeneous before experimental treatment. Objective halitosis in the experimental group, measured by a portable halitosis detector (t= -8.34, p<.001) was significantly lower than the control group. Subjective halitosis was significantly lower in the experimental group (t= -9.29, p<.001). Salivary pH was significantly different between two groups (t=8.81, p<.001). Oral status was significantly better in the experimental group (t= -13.31, p<.001). CONCLUSION: These findings indicate that oral gargling using A-solution is effective in reducing patient halitosis, and improving oral status.
Adult
;
Female
;
Genital Diseases, Female/surgery
;
Halitosis/*prevention & control
;
Humans
;
Hydrogen-Ion Concentration
;
Middle Aged
;
Mouthwashes/*therapeutic use
;
Preoperative Care
;
Saliva/chemistry

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