1.Hysteroscopic adhesiolysis and fertility outcomes of intrauterine adhesions due to endometrial tuberculosis.
Jianfa JIANG ; Dabao XU ; Yimin YANG
Journal of Central South University(Medical Sciences) 2025;50(1):52-60
OBJECTIVES:
Endometrial tuberculosis, which commonly affects women of reproductive age, is a significant cause of intrauterine adhesions (IUA), potentially leading to hypomenorrhea, amenorrhea, and infertility. Hysteroscopic adhesiolysis is the primary treatment for IUA; however, studies specifically addressing its efficacy in tuberculosis-induced IUA remain scarce. This study aims to evaluate the therapeutic outcomes of hysteroscopic adhesiolysis for IUA caused by endometrial tuberculosis.
METHODS:
This retrospective cohort study included patients diagnosed with tuberculosis-induced IUA who underwent hysteroscopic adhesiolysis at the Third Xiangya Hospital of Central South University between May 2014 and October 2022. Clinical data including age, medical history, adhesion severity, surgical treatment, and reproductive outcomes were analyzed.
RESULTS:
Among 39 patients identified, 2 were lost to follow-up. A total of 37 patients were included, with a follow-up duration ranging from 6 months to 9 years. Hypomenorrhea was reported in 24 (64.9%) patients, secondary amenorrhea in 10 (27.0%) patients, and normal menstruation in 3 (8.1%) patients. Most patients presented with primary infertility (59.5%), and only 2 (5.4%) had secondary infertility. The median American Fertility Society (AFS) score at initial assessment was 10 (range, 8-12); 8 (21.6%) patients had moderate IUA, and 29 (78.4%) had severe IUA. A total of 86 surgical procedures were performed across 37 patients, with 27 patients undergoing 2 or more surgeries. Postoperatively, 25 (67.6%) patients achieved normalization of the uterine cavity, while 12 (32.4%) still had a reduced cavity. Only 7 (18.9%) patients had a grossly normal endometrium at the final surgery, all of whom had moderate adhesions at the initial procedure. Menstrual flow returned to normal in 12 (32.4%) patients, while 25 (67.6%) continued to experience hypomenorrhea. Of 29 patients who attempted in vitro fertilization and embryo transfer (IVF-ET), only 6 (20.7%) conceived. Among these, 4 (13.8%) delivered at term via cesarean section; one case was complicated by postpartum hemorrhage due to uterine atony and another by placental adhesion.
CONCLUSIONS
Endometrial tuberculosis can lead to severe IUA. Hysteroscopic adhesiolysis facilitates cavity restoration and improvement of menstrual conditions, but the overall reproductive outcomes remain suboptimal.
Humans
;
Female
;
Hysteroscopy/methods*
;
Tissue Adhesions/etiology*
;
Retrospective Studies
;
Adult
;
Uterine Diseases/etiology*
;
Infertility, Female/surgery*
;
Treatment Outcome
;
Tuberculosis, Female Genital/surgery*
;
Fertility
;
Pregnancy
2.Combination Effects of Capsicum Plaster at the Korean Hand Acupuncture Points K-D2 with Prophylactic Antiemetic on Postoperative Nausea and Vomiting after Gynecologic Laparoscopy.
Hyun Jung JUNG ; Sang Youn PARK
Journal of Korean Academy of Nursing 2013;43(2):215-224
PURPOSE: This study was done to evaluate the combination effects of capsicum plaster at the Korean hand acupuncture points K-D2 with prophylactic antiemetic on Postoperative Nausea and Vomiting (PONV). METHODS: An experimental research design (a randomized, a double-blinded, and a placebo-control procedure) was used. The participants were female patients undergoing gynecologic laparoscopy; the control group (n=34) received intravenous prophylactic ramosetron 0.3mg, while the experimental group (n=34) had Korean Hand Therapy additionally. In the experimental group, capsicum plaster was applied at K-D2 of both 2nd and 4th fingers by means of Korean Hand Therapy for a period of 30 minutes before the induction of anesthesia and removed 8 hours after the laparoscopy. RESULTS: The occurrence of nausea, nausea intensity and need for rescue with antiemetic in the experimental group was significantly less than in the control group 2 hours after surgery. CONCLUSION: Results of the study show capsicum plaster at K-D2 is an effective method for reducing PONV in spite of the low occurrence of PONV because of the prophylactic antiemetic medication.
Acupuncture Points
;
Adult
;
Anesthesia
;
Antiemetics/*therapeutic use
;
Asian Continental Ancestry Group
;
Capsaicin/therapeutic use
;
Capsicum/*chemistry
;
Double-Blind Method
;
Female
;
Fingers
;
Genital Diseases, Female/*surgery
;
Humans
;
Laparoscopy/adverse effects
;
Middle Aged
;
Postoperative Nausea and Vomiting/*drug therapy/etiology
;
Republic of Korea
;
Time Factors
;
Vomiting/*drug therapy/etiology
3.Influence of auricular point sticking on incidence of nausea and vomiting and analgesia effect after gynecological laparoscopy.
Li-Hong ZHANG ; Chun-Ling CAO ; Jing-Zhu LI ; Mei-Lun CHEN ; Ming-Shan WANG ; Chun-Yang DAI
Chinese Acupuncture & Moxibustion 2013;33(4):339-341
OBJECTIVETo observe the influence of auricular point sticking on incidence of nausea and vomiting and analgesia effect after gynecological laparoscopy, and provide evidence for clinical application of auricular point sticking.
METHODSOne hundred and twenty cases of selective gynecological laparoscopy under general anesthesia were randomly divided into an auricular point sticking group and a placebo group, 60 cases in each group. In the auricular point sticking group, the auricular point sticking with vaccaria seeds was applied at Shenmen (TF 4), Wei (CO 4) and Jiaogan (AH 6a) before the operation and 1, 5, 9, 23 h after the operation, which were pressed 5 min each point each time. The two ears were proceeded at the same time. In the placebo group, the same point selection, sticking paste was used as the auricular point sticking group, but no sticking or pressing with vaccaria seeds was adopted. The incidence of nausea and vomiting, the usage rate of tropisetron and morphine within 24 hours of the operation, as well as the score of visual analogue scale (VAS) and other adverse reactions at 2, 6, 10, 24 h after the operation were observed respectively.
RESULTSCompared with the placebo group, the incidence of nausea and vomiting [31.7% (19/60), 16.7% (10/60) vs 58.3% (35/60), 35.0% (21/60)], the usage rate of tropisetron [21.7% (13/60) vs 48.3% (29/60)] and morphine [18.3% (11/60) vs 38.3% (23/60)], the VAS scores at all different time points in the auricular point sticking group were all decreased (all P < 0.05), and no adverse reaction was observed.
CONCLUSIONThe auricular point sticking could significantly decrease the incidence of nausea and vomiting in patients of gynecological laparoscopy and has positive analgesic effect.
Acupuncture Analgesia ; Acupuncture Points ; Acupuncture, Ear ; Adult ; Female ; Genital Diseases, Female ; surgery ; Gynecology ; Humans ; Laparoscopy ; adverse effects ; Middle Aged ; Nausea ; etiology ; therapy ; Vomiting ; etiology ; therapy ; Young Adult
4.Thirty-eight cases of abdominal incisional fat necrosis after gynecologic operation treated with moxibustion.
Chinese Acupuncture & Moxibustion 2012;32(8):683-684
Abdomen
;
surgery
;
Adult
;
Fat Necrosis
;
etiology
;
therapy
;
Female
;
Genital Diseases, Female
;
complications
;
surgery
;
Humans
;
Middle Aged
;
Moxibustion
;
Postoperative Complications
;
etiology
;
therapy
;
Young Adult
5.Diagnosis of non-sexually transmitted diseases in genitalia.
National Journal of Andrology 2008;14(11):963-967
Highly transient population, multiple sexual partners and high prevalence of unprotected sex behaviors suggest a potential rapid spread of sexually transmitted diseases (STD) in China. However, there are some 200 non-sexually transmitted diseases involving the genitalia, etiologically falling into 23 types. To avoid unnecessary medical disputes, enough attention should be paid to the differential diagnosis of non-sexually transmitted diseases in the genitalia.
Female
;
Genital Diseases, Female
;
diagnosis
;
etiology
;
Genital Diseases, Male
;
diagnosis
;
etiology
;
Genital Neoplasms, Male
;
diagnosis
;
Humans
;
Male
;
Skin Diseases, Infectious
;
diagnosis
;
etiology
;
Skin Neoplasms
;
diagnosis
6.An unexpected presentation of endometriosis--a "parasitic" cyst of the bowel in a menopausal woman on hormone therapy.
Citra Nurfarah MATTAR ; Brendan PANG ; Yoke Fai FONG
Annals of the Academy of Medicine, Singapore 2008;37(1):69-71
INTRODUCTIONThis report describes a "parasitic" endometriotic cyst of the small bowel.
CLINICAL PICTUREA menopausal woman with a pelvic mass presenting years after commencing hormone therapy.
TREATMENTWe performed laparoscopic excision of a cystic tumour attached to the small bowel with a solitary vascular pedicle.
OUTCOMEHistology confirmed it to be an endometriotic cyst of ovarian origin, probably resulting from spillage during previous surgery and reactivation with hormone therapy.
CONCLUSIONSWe discuss the possible aetiology of this unusual presentation of endometriosis and review the literature on parasitic gynaecological tumours.
Cysts ; pathology ; Endometriosis ; diagnosis ; etiology ; Estrogen Replacement Therapy ; Female ; Genital Diseases, Female ; Humans ; Intestine, Small ; physiopathology ; Middle Aged
7.Study on the microbial and parasitological etiology of the lower genital tract infections in women with the reproductive ages
Journal of Practical Medicine 2002;435(11):32-34
2534 women with ages of 18- 45 in 6 different areas were examined and tested. The results have shown that the rate of genital tract infection was different from one to another: urban of Ha Noi: 41,48%, suburb of Ha Noi: 59,35%, Thai Binh: 56,98, Ha Nam 58,39%, suburb of Hai duong: 52%, mountaine of Nghe an: 64,07%. The most common etiology was candida (14,7 - 42,8%) and G. vaginalis (8,7- 28,74%). The others were staphylococus aureus, E.coli, stretococcus group D and Enterobacilli.
Female Genital Diseases and Pregnancy Complications
;
Etiology
;
women
;
Reproduction
8.An epidemiological survey on reproductive track infection and the investigation on syndromic approach on vaginal discharge.
Min LIU ; Guang ZENG ; Linghua ZHANG ; Zhiqiang LIU ; Shiqin LI
Chinese Journal of Epidemiology 2002;23(6):422-426
OBJECTIVETo investigate the reproductive track infection (RTI) situation and risk factors for cervical infection (Neisseria gonorrhoeae or Chlamydia trachomatis) among different kinds of women of childbearing age in Shenzhen city, China. To assess the feasibility of the syndromic approach for vaginal discharge.
METHODSThe survey was administrated to 4,744 eligible women in Shenzhen city during October 2001 and April 2002. The subjects included three different kinds of population: 3,895 cases of general population, 438 STD/gynecological clinic outpatients and 411 people with high risk behavior. Gynaecologic examination and RTI laboratory diagnosis were performed for each subject. PCR method-based test was used to detect the Neisseria gonorrhoeae and Chlamydia trachomatis infection. Standardized questionnaire were designed to collect the information about RTI related behaviors, and history of marriage and child bearing, et al. The risk factors, symptoms and signs of cervical infection were analyzed. Syndromic approach was established and its feasibility was assessed.
RESULTS27.6% of women in Shenzhen were infected with at least one kind of RTI, including 5.0% with cervical infection. The risk factors for cervical infection were: individuals having had new sex partner within last 3 months (OR = 1.6, 95% CI: 1.1 - 2.4), having had the experience of abortion (OR = 1.6, 95% CI: 1.1 - 2.4), aged 25 or less (OR = 1.6, 95% CI: 1.1 - 2.4) and never using condom during sex intercourse (OR = 1.7, 95% CI: 1.1 - 2.4). The sensitivity of syndromic approach of risk assessment and signs for cervical infection among general population was 63.8%, while specificity was 55.1% with the positive predictive value 7.0%.
CONCLUSIONSRTI infection was common among all three kinds of childbearing women in Shenzhen city. The prevalence of RTI was the highest among high risk population, followed by STD/gynecological clinic outpatients. The efficacy of syndromic approach for cervical infection in general population was not ideal.
China ; epidemiology ; Female ; Genital Diseases, Female ; epidemiology ; etiology ; Humans ; Risk Assessment ; Risk Factors ; Uterine Cervical Diseases ; epidemiology ; Vaginal Discharge ; epidemiology ; etiology
9.A case of factor V deficiency presenting as menorrhagia
M. Sapuri ; A B. Amoa ; G. Kariwiga ; J. White
Papua New Guinea medical journal 1997;40(2):92-95
Factor V deficiency is a rare hereditary disorder. We report a patient with factor V deficiency who presented with menorrhagia and pelvic haematoma. The Haematology Department at the Royal Brisbane Hospital performed the definitive factor assays leading to the diagnosis. The challenges of her management were obtaining adequate supplies of factor V and her socioeconomic circumstances. The main future challenge will be the supervision of her pregnancies.
Blood Coagulation Factors - analysis
;
Factor V Deficiency - complications
;
Factor V Deficiency - diagnosis
;
Female
;
Genital Diseases, Female - etiology
;
Hematoma - etiology
;
Humans
;
Menorrhagia - etiology
10.Naeng: A Korean Folk Illness, its Ethnography and its Epidemiology.
Young Key KIM ; D SICH ; Tai Keun PARK ; Duck Hee KANG
Yonsei Medical Journal 1980;21(2):147-155
No abstract available.
Anthropology, Cultural
;
Female
;
Genital Diseases, Female/epidemiology*
;
Genital Diseases, Female/etiology
;
Genital Diseases, Female/therapy
;
Human
;
Korea
;
Medicine, Traditional*

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