1.Advances in managing sepsis-associated gastrointestinal dysfunction using Batri-7:insights from traditional Mongolian medicine
Gele QING ; Yunbilige WU ; Tejin BA ; Bagenna BAO ; Hao HAO
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2024;31(5):634-637
Sepsis is one of the common diseases in the intensive care unit (ICU),and its pathophysiological mechanism is characterized by a dysregulated host response to infection leading to multiple organ dysfunction. Statistical data indicate that approximately 20.6% of ICU patients have sepsis. Sepsis is prone to cause gastrointestinal dysfunction and acute damage to organs such as the lungs,heart,and kidneys. During sepsis,the intestinal mucosal barrier,as an essential component of normal intestinal physiological function,effectively prevents harmful pathogens from entering the organs and the bloodstream,thereby reducing the risk of organ damage associated with sepsis. However,due to this vulnerability,the intestine also becomes one of the first organs attacked by bacteria and viruses. Therefore,maintaining the integrity of the intestinal mucosal barrier is crucial for improving the absorption of enteral nutrients in patients with severe sepsis and enhancing their ability against microbial entry into the bloodstream,thereby inhibiting the progression of sepsis,which carries significant clinical importance. The Mongolian medicine Bateri-7 is a commonly used formula in Mongolian hospitals in Inner Mongolia Autonomous Region,known for its antibacterial properties,and is applied in the treatment of inflammatory diseases such as enteritis and pneumonia. This medication is routinely used in our hospital's department of emergency and critical care medicine for treating gastrointestinal dysfunction in sepsis,severe pneumonia,and other intestinal inflammatory diseases. This paper will focus on discussing the definition of sepsis,its pathogenesis,the function of the intestinal barrier,and the therapeutic and protective effects of Mongolian medicine Bateri-7 in addressing intestinal barrier dysfunction in sepsis patients,providing theoretical support for the clinical application of Bateri-7.
2.Advances in managing sepsis-associated gastrointestinal dysfunction using Batri-7:insights from traditional Mongolian medicine
Gele QING ; Yunbilige WU ; Tejin BA ; Bagenna BAO ; Hao HAO
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2024;31(5):634-637
Sepsis is one of the common diseases in the intensive care unit (ICU),and its pathophysiological mechanism is characterized by a dysregulated host response to infection leading to multiple organ dysfunction. Statistical data indicate that approximately 20.6% of ICU patients have sepsis. Sepsis is prone to cause gastrointestinal dysfunction and acute damage to organs such as the lungs,heart,and kidneys. During sepsis,the intestinal mucosal barrier,as an essential component of normal intestinal physiological function,effectively prevents harmful pathogens from entering the organs and the bloodstream,thereby reducing the risk of organ damage associated with sepsis. However,due to this vulnerability,the intestine also becomes one of the first organs attacked by bacteria and viruses. Therefore,maintaining the integrity of the intestinal mucosal barrier is crucial for improving the absorption of enteral nutrients in patients with severe sepsis and enhancing their ability against microbial entry into the bloodstream,thereby inhibiting the progression of sepsis,which carries significant clinical importance. The Mongolian medicine Bateri-7 is a commonly used formula in Mongolian hospitals in Inner Mongolia Autonomous Region,known for its antibacterial properties,and is applied in the treatment of inflammatory diseases such as enteritis and pneumonia. This medication is routinely used in our hospital's department of emergency and critical care medicine for treating gastrointestinal dysfunction in sepsis,severe pneumonia,and other intestinal inflammatory diseases. This paper will focus on discussing the definition of sepsis,its pathogenesis,the function of the intestinal barrier,and the therapeutic and protective effects of Mongolian medicine Bateri-7 in addressing intestinal barrier dysfunction in sepsis patients,providing theoretical support for the clinical application of Bateri-7.
3.Observation on the role of Mongolia medicine pulse diagnosis in evaluation of disease situation of critically ill patients in department of emergency
Bagenna BAO ; Da MAN ; Haitao DONG ; Gele QING ; Guofu WEI ; Siriguleng LIU ; Shuangquan HE
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2018;25(3):314-315
Objective To discuss the feasibility of Mongolian medicine pulse diagnosis in assessment of the disease situation of acute critically ill patients. Methods The clinical data of acute critically ill patients admitted in the Department of Emergency of Inner Mongolia International Mongolian Medical Hospital from December 2015 to December 2017 were retrospectively analyzed, and the role of Mongolian medicine pulse diagnosis in the evaluation of disease situations of patients with acute critical illness was observed. Results The improved early warning score (MEWS) at admission was carried out for all the patients in the Emergency Department of this hospital, 996 critically ill patients with their MEWS score ≥ 5 scores in accord with the inclusion criteria were allowed to undergo the Mongolian medicine pulse diagnosis, and of them, 654 patients showed specific changes in pulse condition. Shock appeared rapid pulse, microphygmia in pulse diagnosis of Mongolian medicine, severe anemia appeared the slippery pulse and rapid pulse in pulse diagnosis of Mongolian medicine, severe arrhythmia appeared rapid pulse and slow pulse in pulse diagnosis of Mongolian medicine, acute myocardial infarction appeared rapid pulse, weak pulse and slow pulse in pulse diagnosis of Mongolian medicine, insufficiency of heart function appeared rapid pulse and weak pulse in pulse diagnosis of Mongolian medicine, hypertension complicated with cerebral hemorrhage with forceful pulse and pulsus pulse are all suggestive of critical condition. Conclusions The specific changes in pulse condition of patients with acute critical illness in Mongolian medicine are helpful to the assessment of the patient's condition. This method can also be used as one of the tools for rapid assessment of disease situation in critical patients before going to hospital or in the hospital.

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