1.Assessment of upper limb rehabilitation exercise participation based on trajectory errors and surface electromyography signals.
Xiaohong WANG ; Jian LYU ; Shengbo FANG
Journal of Biomedical Engineering 2025;42(2):308-317
At present, upper limb motor rehabilitation relies on specific rehabilitation aids, ignoring the initiative of upper limb motor of patients in the middle and late stages of rehabilitation. This paper proposes a fuzzy evaluation method for active participation based on trajectory error and surface electromyography (sEMG) for patients who gradually have the ability to generate active force. First, the level of motor participation was evaluated using trajectory error signals represented by computer vision. Then, the level of physiological participation was quantified based on muscle activation (MA) characterized by sEMG. Finally, the motor performance and physiological response parameters were input into the fuzzy inference system (FIS). This system was then used to construct the fuzzy decision tree (FDT), which ultimately outputs the active participation level. A controlled experiment of upper limb flexion and extension exercise in 16 healthy subjects demonstrated that the method presented in this paper was effective in quantifying difference in the active participation level of the upper limb in different force-generating states. The calculation results of this method and the active participation assessment method based on sEMG during the task cycle showed that the active participation evaluation values of both methods peaked in the initial cycle: (82.34 ± 9.3) % for this paper's method and (78.44 ± 7.31) % for the sEMG method. In the subsequent cycles, the values of both showed a dynamic change trend of rising first and then falling. Trend consistency verifies the effectiveness of the active participation assessment strategy in this paper, providing a new idea for quantifying the participation level of patients in middle and late stages of upper limb rehabilitation without special equipment mediation.
Humans
;
Electromyography/methods*
;
Upper Extremity/physiology*
;
Fuzzy Logic
;
Exercise Therapy/methods*
;
Muscle, Skeletal/physiology*
;
Male
2.Application Status of Machine Learning in Assisted Diagnosis Techniques of Cardiovascular Diseases.
Pinliang LIAO ; Zihong WANG ; Miao TIAN ; Hong CHAI ; Xiaoyu CHEN
Chinese Journal of Medical Instrumentation 2025;49(1):24-34
In recent years, cardiovascular disease has become a common disease. With the development of machine learning and big data technologies, the processing ability of electrocardiogram (ECG) signals has been greatly enhanced through new computer technologies, enabling the auxiliary diagnosis technology for cardiovascular disease (CVD) to achieve new improvements. This article discusses the application of machine learning in ECG processing, especially in the auxiliary diagnosis of diseases. Firstly, the conventional signal preprocessing methods are introduced, and then the EEG signal processing methods based on feature extraction and fuzzy classification are explored. Secondly, the application of auxiliary diagnosis in CVD is further summarized. Finally, the advantages and disadvantages of the two methods are analyzed, and based on this, a design of an auxiliary diagnostic system compatible with the two methods is proposed, providing a new perspective for similar applied researches in the future.
Machine Learning
;
Cardiovascular Diseases/diagnosis*
;
Humans
;
Electrocardiography
;
Signal Processing, Computer-Assisted
;
Diagnosis, Computer-Assisted
;
Fuzzy Logic
;
Electroencephalography
3.Failure Diagnosis Analysis of Medical Equipment Based on Fault Tree and Fuzzy Bayesian Network.
Chinese Journal of Medical Instrumentation 2025;49(5):540-544
OBJECTIVE:
To enhance the reliability of medical equipment, this study aims to develop a failure cause diagnosis model and provide rational suggestions for efficient equipment use.
METHODS:
Combine fault tree analysis (FTA) to identify basic events causing equipment failure and calculate their prior probabilities. Obtain conditional probability tables for each node through expert assessment. Integrate triangular fuzzy number theory with Bayesian network (BN) to construct a fuzzy Bayesian network (FBN) for posterior probability inference and sensitivity analysis.
RESULTS:
Using endoscopes as the subject, the analysis shows that the model accurately calculates the endoscope failure probability at 0.385%, and identifies the key causes: improper cleaning ( X5, posterior probability 0.36064), untimely fault detection ( X8, posterior probability 0.23571), irregular transportation ( X6, posterior probability 0.11344), and natural aging ( X10, posterior probability 0.11377). Sensitivity analysis also confirms their influence weights (mutual information values are 0.00749, 0.00591, 0.00202, 0.00174).
CONCLUSION
The model can accurately perform quantitative analysis and rapid fault location of medical equipment failures, enabling effective preventive measures.
Bayes Theorem
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Fuzzy Logic
;
Equipment Failure Analysis/methods*
;
Equipment Failure
;
Algorithms
4.Biotechnical system based on fuzzy logic prediction for surgical risk classification using analysis of current-voltage characteristics of acupuncture points.
Sergey FILIST ; Riad Taha AL-KASASBEH ; Olga SHATALOVA ; Nikolay KORENEVSKIY ; Ashraf SHAQADAN ; Zeinab PROTASOVA ; Maksim ILYASH ; Mikhail LUKASHOV
Journal of Integrative Medicine 2022;20(3):252-264
OBJECTIVE:
This study aimed to develop expert fuzzy logic model to assist physicians in the prediction of postoperative complications of prostatic hyperplasia before surgery.
METHODS:
A method for classification of surgical risks was developed. The effect of rotation of the current-voltage characteristics at biologically active points (acupuncture points) was used for the formation of classifier descriptors. The effect determined reversible and non-reversible changes in electrical resistance at acupuncture points with periodic exposure to a sawtooth probe current. Then, the developed method was tested on the prediction of the success of surgical treatment of benign prostatic hyperplasia.
RESULTS:
Input descriptors were obtained from collected data including current-voltage characteristics of 5 acupuncture points and composed of 27 arrays feeding in the model. The maximum diagnostic sensitivity of the classifier for the success of a surgical operation in the control sample was 88% and for testing data set prediction accuracy was 97%.
CONCLUSION
The use of tuples of current-voltage characteristic descriptors of acupuncture points in the classifiers could be used to predict the success of surgical treatment with satisfactory accuracy. The model can be a valuable tool to support physicians' diagnosis.
Acupuncture Points
;
Acupuncture Therapy
;
Fuzzy Logic
5.Application of fuzzy analytic hierarchy process in risk assessment in medicine related fields.
Chinese Journal of Epidemiology 2022;43(5):766-770
Risks exist in medicine related fields, which cannot be defined and quantified precisely. It is necessary to adopt a method for the risk assessment of uncertain and fuzzy phenomenon. This paper summarizes the thinking, procedure, advantage and application of fuzzy analytic hierarchy process in the risk assessment in medicine related fields for the purpose of providing reference for its further application.
Analytic Hierarchy Process
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Fuzzy Logic
;
Humans
;
Risk Assessment/methods*
6.Research on the cardiovascular function evaluation system based on noninvasive detection indices.
Xiaorui SONG ; Gaoyang LI ; Xuezheng WANG ; Shigang WANG ; Xiangming FAN ; Yao YANG ; Aike QIAO
Journal of Biomedical Engineering 2019;36(4):649-656
Based on the noninvasive detection indeices and fuzzy mathematics method, this paper studied the noninvasive, convenient and economical cardiovascular health assessment system. The health evaluation index of cardiovascular function was built based on the internationally recognized risk factors of cardiovascular disease and the noninvasive detection index. The weight of 12 indexes was completed by the analytic hierarchy process, and the consistency test was passed. The membership function, evaluation matrix and evaluation model were built by fuzzy mathematics. The introducted methods enhanced the scientificity of the evaluation system. Through the Kappa consistency test, McNemer statistical results ( = 0.995 > 0.05) and Kappa values (Kappa = 0.616, < 0.001) suggest that the comprehensive evaluation results of model in this paper are relatively consistent with the clinical, which is of certain scientific significance for the early detection of cardiovascular diseases.
Cardiovascular Diseases
;
diagnosis
;
Cardiovascular System
;
Fuzzy Logic
;
Humans
;
Models, Cardiovascular
;
Research
7.Design of Portable Fuzzy Diagnosis Instrument for ECG Signal Based on Internet of Things.
Kai WANG ; Jicheng XU ; Yu ZHANG
Chinese Journal of Medical Instrumentation 2019;43(5):341-344
OBJECTIVE:
A method for dynamically collecting and processing ECG signals was designed to obtain classification information of abnormal ECG signals.
METHODS:
Firstly, the ECG eigenvectors were acquired by real-time acquisition of ECG signals combined with discrete wavelet transform, and then the ECG fuzzy information entropy was calculated. Finally, the Euclidean distance was used to obtain the semantic distance of ECG signals, and the classification information of abnormal signals was obtained.
RESULTS:
The device could effectively identify abnormal ECG signals on an embedded platform based on the Internet of Things, and improved the diagnosis accuracy of heart diseases.
CONCLUSIONS
The fuzzy diagnosis device of ECG signal could accurately classify the abnormal signal and output an online signal classification matrix with a high confidence interval.
Algorithms
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Arrhythmias, Cardiac
;
Electrocardiography
;
Fuzzy Logic
;
Heart Diseases
;
diagnosis
;
Humans
;
Internet
;
Signal Processing, Computer-Assisted
;
Wavelet Analysis
8.Qualitative analysis of a sulfur-fumigated Chinese herbal medicine by comprehensive two-dimensional gas chromatography and high-resolution time of flight mass spectrometry using colorized fuzzy difference data processing.
Hao CAI ; Gang CAO ; Hong-Yan ZHANG
Chinese journal of integrative medicine 2017;23(4):261-269
OBJECTIVETo investigate the chemical transformation of volatile compounds in sulfur-fumigated Radix Angelicae Sinensis.
METHODSA comprehensive two-dimensional gas chromatography (GC×GC) and high-resolution time-of-flight mass spectrometry (HR-TOF/MS) with colorized fuzzy difference (CFD) method was used to investigate the effect of sulfur-fumigation on the volatile components from Radix Angelicae Sinensis.
RESULTSTwenty-five compounds that were found in sun-dried samples disappeared in sulfur-fumigated samples. Seventeen volatile components including two sulfur-containing compounds were newly generated for the first time in volatile oils of sulfur-fumigated Radix Angelicae Sinensis.
CONCLUSIONThe strategy can be successfully applied to rapidly and holistically discriminate sun-dried and sulfur-fumigated Radix Angelicae Sinensis. GC×GC-HR-TOF/MS based CFD is a powerful and feasible approach for the global quality evaluation of Radix Angelicae Sinensis as well as other herbal medicines.
Color ; Drugs, Chinese Herbal ; analysis ; Fumigation ; Fuzzy Logic ; Gas Chromatography-Mass Spectrometry ; methods ; Oils, Volatile ; analysis ; Reference Standards ; Sulfur ; analysis ; Volatile Organic Compounds ; analysis
9.Systematic Review of Data Mining Applications in Patient-Centered Mobile-Based Information Systems.
Mina FALLAH ; Sharareh R NIAKAN KALHORI
Healthcare Informatics Research 2017;23(4):262-270
OBJECTIVES: Smartphones represent a promising technology for patient-centered healthcare. It is claimed that data mining techniques have improved mobile apps to address patients’ needs at subgroup and individual levels. This study reviewed the current literature regarding data mining applications in patient-centered mobile-based information systems. METHODS: We systematically searched PubMed, Scopus, and Web of Science for original studies reported from 2014 to 2016. After screening 226 records at the title/abstract level, the full texts of 92 relevant papers were retrieved and checked against inclusion criteria. Finally, 30 papers were included in this study and reviewed. RESULTS: Data mining techniques have been reported in development of mobile health apps for three main purposes: data analysis for follow-up and monitoring, early diagnosis and detection for screening purpose, classification/prediction of outcomes, and risk calculation (n = 27); data collection (n = 3); and provision of recommendations (n = 2). The most accurate and frequently applied data mining method was support vector machine; however, decision tree has shown superior performance to enhance mobile apps applied for patients’ self-management. CONCLUSIONS: Embedded data-mining-based feature in mobile apps, such as case detection, prediction/classification, risk estimation, or collection of patient data, particularly during self-management, would save, apply, and analyze patient data during and after care. More intelligent methods, such as artificial neural networks, fuzzy logic, and genetic algorithms, and even the hybrid methods may result in more patients-centered recommendations, providing education, guidance, alerts, and awareness of personalized output.
Artificial Intelligence
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Data Collection
;
Data Mining*
;
Decision Trees
;
Delivery of Health Care
;
Early Diagnosis
;
Education
;
Follow-Up Studies
;
Fuzzy Logic
;
Humans
;
Information Systems*
;
Mass Screening
;
Methods
;
Mobile Applications
;
Patient Care
;
Self Care
;
Smartphone
;
Statistics as Topic
;
Support Vector Machine
;
Telemedicine
10.A computer-aided diagnostic system for kidney disease.
Farzad Firouzi JAHANTIGH ; Behnam MALMIR ; Behzad Aslani AVILAQ
Kidney Research and Clinical Practice 2017;36(1):29-38
BACKGROUND: Disease diagnosis is complicated since patients may demonstrate similar symptoms but physician may diagnose different diseases. There are a few number of investigations aimed to create a fuzzy expert system, as a computer aided system for disease diagnosis. METHODS: In this research, a cross-sectional descriptive study conducted in a kidney clinic in Tehran, Iran in 2012. Medical diagnosis fuzzy rules applied, and a set of symptoms related to the set of considered diseases defined. The input case to be diagnosed defined by assigning a fuzzy value to each symptom and then three physicians asked about each suspected diseases. Then comments of those three physicians summarized for each disease. The fuzzy inference applied to obtain a decision fuzzy set for each disease, and crisp decision values attained to determine the certainty of existence for each disease. RESULTS: Results indicated that, in the diagnosis of seven cases of kidney disease by examining 21 indicators using fuzzy expert system, kidney stone disease with 63% certainty was the most probable, renal tubular was at the lowest level with 15%, and other kidney diseases were at the other levels. The most remarkable finding of this study was that results of kidney disease diagnosis (e.g., kidney stone) via fuzzy expert system were fully compatible with those of kidney physicians. CONCLUSION: The proposed fuzzy expert system is a valid, reliable, and flexible instrument to diagnose several typical input cases. The developed system decreases the effort of initial physical checking and manual feeding of input symptoms.
Diagnosis
;
Expert Systems
;
Fuzzy Logic
;
Humans
;
Iran
;
Kidney Calculi
;
Kidney Diseases*
;
Kidney*

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