Objective:To explore the nurses' willingness to stay at work in ClassⅢ hospitals of Chinese medicine, and provide a reference for developing retention strategies.Methods:From May to September 2017, a total of 1 080 nurses from 3 ClassⅢ hospitals of Chinese medicine in Western, Central and Eastern China were selected by cluster sampling and investigated with the demographic data questionnaire, Nurses' Willingness to Stay at Work Questionnaire, Job Satisfaction Scale, Job Control Scale and Transformational Leadership Questionnaire. Multiple hierarchical regression analysis was used to analyze the influencing factors of nurses' willingness to stay at work. A total of 1 080 questionnaires were distributed, and 918 valid questionnaires were collected, accounting for an effective recovery rate of 85.00%.Results:The average score of the Nurses' Willingness to Stay at Work Questionnaire in the 918 Chinese medicine nurses was (3.45±0.63) . There were statistically significant differences in the scores of the Nurses' Willingness to Stay at Work Questionnaire between nurses with different positions, job titles, forms of employment, number of night shifts per month, and monthly income ( P< 0.05) . The results of multiple hierarchical regression analysis revealed that job titles, number of night shifts per month, job satisfaction, work efficiency control, and vision incentives were the main factors affecting nurses' willingness to stay at work ( P < 0.05) , accounting for 28.0% of the total variation. Conclusions:The nurses' willingness to stay at work in hospitals of Chinese medicine is at a medium level, and hospital managers should appropriately adjust night shifts, give nurses appropriate incentives, and strengthen their job autonomy, so as to improve their job satisfaction and stabilize their willingness to stay at work.