1.Fatigue driving detection based on prefrontal electroencephalogram asymptotic hierarchical fusion network.
Jiazheng SUN ; Weimin LI ; Ningling ZHANG ; Cai CHEN ; Shengzhe WANG ; Fulai PENG
Journal of Biomedical Engineering 2025;42(3):544-551
Fatigue driving is one of the leading causes of traffic accidents, posing a significant threat to drivers and road safety. Most existing methods focus on studying whole-brain multi-channel electroencephalogram (EEG) signals, which involve a large number of channels, complex data processing, and cumbersome wearable devices. To address this issue, this paper proposes a fatigue detection method based on frontal EEG signals and constructs a fatigue driving detection model using an asymptotic hierarchical fusion network. The model employed a hierarchical fusion strategy, integrating an attention mechanism module into the multi-level convolutional module. By utilizing both cross-attention and self-attention mechanisms, it effectively fused the hierarchical semantic features of power spectral density (PSD) and differential entropy (DE), enhancing the learning of feature dependencies and interactions. Experimental validation was conducted on the public SEED-VIG dataset. The proposed model achieved an accuracy of 89.80% using only four frontal EEG channels. Comparative experiments with existing methods demonstrate that the proposed model achieves high accuracy and superior practicality, providing valuable technical support for fatigue driving monitoring and prevention.
Humans
;
Electroencephalography/methods*
;
Automobile Driving
;
Fatigue/diagnosis*
;
Accidents, Traffic/prevention & control*
;
Signal Processing, Computer-Assisted
;
Neural Networks, Computer
;
Algorithms
;
Prefrontal Cortex/physiology*
2.Comparison of muscle injury between piriformis muscle release and preservation in total hip arthroplasty via supercapsular percutaneously-assisted total hip approach.
Fengping GAN ; Qibiao ZHANG ; Fulai MO ; Linjie LI ; Fei ZHENG ; Xinxin LIN ; Hao QIN
Chinese Journal of Reparative and Reconstructive Surgery 2025;39(6):715-722
OBJECTIVE:
To compare the effects of piriformis muscle release versus preservation in total hip arthroplasty (THA) via supercapsular percutaneously-assisted total hip (SuperPATH) approach on muscle injury.
METHODS:
Forty-nine patients undergoing initial THA via SuperPATH approach between June 2022 and June 2023 were randomly divided into two groups, with 24 patients in trial group and 25 patients in control group. The trial group received piriformis muscle release intraoperatively, whereas the control group underwent muscle preservation. There was no significant difference in baseline data such as gender, age, body mass index, disease type, American Society of Anesthesiologists (ASA) grading, and preoperative muscle infiltration, muscle atrophy, muscle injury serological indicators, Harris score, etc. ( P>0.05). The incision length, operation time, intraoperative blood loss, total blood loss, hospital stay, preoperative and postoperative 1-day muscle injury serological indicators [including creatine kinase (CK) and lactic dehydrogenase (LDH)], and incidence of complications between two groups were recorded. Harris score was used to evaluate the recovery of hip joint function. MRI was used to evaluate the extent of hip muscle injuries (gluteus minimus, gluteus medius, piriformis, obturator internus, quadratus femoris), including tendon integrity, degree of muscle fat infiltration, and degree of muscle atrophy preoperative and 1 year postoperatively.
RESULTS:
The operation time, intraoperative blood loss, and total blood loss in the trial group were significantly shorter than those in the control group ( P<0.05). There was no significant difference in the incision length and length of hospital stay between the two groups ( P>0.05). Both groups showed a significant increase in serum CK and LDH levels on postoperative day 1 compared to preoperative levels ( P<0.05), but there was no significant difference between the two groups ( P>0.05). All patients were followed up, the follow-up time for the trial group and the control group was (14.8±2.8) and (15.1±3.0) months, respectively, with no significant difference ( t=-0.400, P=0.691). Incisions healed by first intention in both groups, with 1 case in the trial group and 2 cases in the control group experiencing venous thrombosis in the calf muscle space. There was no complication such as deep vein thrombosis, pulmonary embolism, hip dislocation, prosthesis loosening, or periprosthetic infection in the lower limbs. There was no significant difference in the incidence of complications between the two groups ( P>0.05). At 1 year after operation, both groups of patients showed a significant increase in Harris scores compared to preoperative levels ( P<0.05), but there was no significant difference between the two groups ( P>0.05). Compared with preoperative results, both groups showed significant fat infiltration in the piriformis and obturator muscles at 1 year after operation ( P<0.05), while there was no significant fat infiltration in the gluteus minimus, gluteus medius, and quadratus femoris muscles ( P>0.05). At 1 year after operation, except for the higher incidence of piriformis muscle fat infiltration in the control group compared to the trial group ( P<0.05), there was no significant difference in the incidence of other muscle infiltrations between the two groups ( P>0.05). At 1 year after operation, both groups of piriformis and obturator muscles showed significant muscle atrophy compared to preoperative levels ( P<0.05). The gluteus minimus and gluteus medius showed mild atrophy compared to preoperative levels, while the maximum transverse diameter of the quadriceps muscle slightly increased, but the differences were not significant ( P>0.05). There was no significant difference in the maximum cross-sectional diameter or cross-sectional area changes of each muscle between the two groups ( P>0.05). At 1 year after operation, the continuity of the gluteus medius and quadratus femoris muscles in both groups was intact. Both groups had some patients with incomplete continuity of the piriformis muscle, obturator internus, and gluteus minimus, but the difference was not significant ( P>0.05).
CONCLUSION
The SuperPATH approach THA may cause injury to the piriformis, gluteus minimus, and obturator internus. The piriformis muscle release does not increase muscle injury, but it can shorten the operation time and reduce bleeding.
Humans
;
Arthroplasty, Replacement, Hip/adverse effects*
;
Male
;
Female
;
Muscle, Skeletal/surgery*
;
Middle Aged
;
Aged
;
Postoperative Complications/epidemiology*
;
Adult
;
Operative Time
;
Muscular Atrophy
;
Creatine Kinase/blood*
;
Length of Stay
;
Treatment Outcome
3.Prevalence trends of hospital-associated infections and variation of pathogens in a three-A children's hospital from 2020 to 2024
Liping DU ; Fulai ZHANG ; Nan GAO ; Chunai ZHANG ; Liyuan FU
Chinese Journal of Nosocomiology 2025;35(22):3426-3430
OBJECTIVE To understand the surveillance data regarding to prevalence of hospital-associated infections(HAIs)in a three-A children's specialized hospital of Henan Province and analyze the change trends so as to pro-vide bases for developing precise prevention strategies and optimizing the allocation of infection control resources.METHODS The data involving the case information,case-time infection rates,infection sites,distribu-tion of departments and pathogens were collected from the children who were hospitalized in Children's Hospital Affiliated to Zhengzhou University from 2020 to 2024.The statistical analysis was performed by SPSS 25.0 soft-ware.RESULTS A total of 460,516 children who were hospitalized for treatment from 2020 to 2024,3700 of whom had hospital-associated infections,with the incidence of HAIs 0.80%;totally 3907 case-times of children had HAIs,with the case-time infection rate 0.85%.The departments ranking the top 5 incidence rates of HAIs were as follows:hematopoietic stem cell transplantation ward,ward 2 of hemooncology department,ward 1 of hemooncology department,ward of rehabilitation center,neonatal surgery department.The lower respiratory tract was the major infection site,accounting for 41.13%.The children who had respiratory system infections accounted for 65.29%.The gram-negative bacteria were dominant among the pathogens causing the HAIs,accounting for 48.15%;the percentage of viruses showed an upward trend.CONCLUSIONS The incidence of HAIs shows fluctu-ating downward trend.It is necessary to further strengthen the refined management and take targeted infection prevention and control measures for the departments at high risk of HAIs and the high-risk links so as to continu-ously improve the medical quality and safety.
4.Building a "six-in-one" community cough and asthma center under a "dual-contract physician" model: a preliminary evaluation
Jianling SONG ; Yunfeng ZHANG ; Shuping ZHENG ; Zheng YE ; Xiaopan LI ; Ben FENG ; Leiming GE ; Yao LIU ; Qihao YAN ; Jiani WANG ; Fulai SHEN ; Sunfang JIANG
Chinese Journal of General Practitioners 2025;24(11):1429-1433
This report evaluates the preliminary outcomes of a "six-in-one" integrated cough and asthma center developed under a dual-contract physician model at the Changfeng Community Health Service Center in Putuo District, Shanghai. By combining the efforts of family doctors and medical specialists, the center integrated six core functions-clinical treatment, prevention, nursing, rehabilitation, pharmacy, and nutrition-into a seamless management system covering screening, diagnosis, therapy, and follow-up. Supported by specialist guidance and teaching clinics, the model significantly enhanced comprehensive respiratory disease management capabilities within the community setting. The initiative not only improved patient health outcomes but also strengthened multidisciplinary collaboration and resource efficiency, offering a replicable example for improving chronic disease management in primary care through integrated and coordinated service delivery.
5.Expert recommendations for diagnosis and treatment routes of severe infections in elderly people based on immune function evaluation
Lina ZHANG ; Chunhui LI ; Zhihong ZUO ; Zhanwen WANG ; Fulai YUAN ; Chuan-chang LI ; Qiong CHEN ; Wei LIU ; Anhua WU ; Zhaoxin QIAN
Chinese Journal of Infection Control 2025;24(8):1027-1032
The aging trend is intensifying currently,but there is still a lack of standardized diagnosis and treat-ment schemes for severe infections in elderly people.This paper focuses on the recommendations for immune-related clinical diagnosis and treatment routes as well as the idea of risk stratified diagnosis and treatment for elderly peo-ple,aiming to effectively prevent infectious diseases in elderly people and perform stratified management through systematic and scientific means of immune function monitoring and regulation,so as to enhance the standardized level of diagnosis and treatment as well as clinical treatment effect of infection in elderly people.
6.Expert recommendations for diagnosis and treatment routes of severe infections in elderly people based on immune function evaluation
Lina ZHANG ; Chunhui LI ; Zhihong ZUO ; Zhanwen WANG ; Fulai YUAN ; Chuan-chang LI ; Qiong CHEN ; Wei LIU ; Anhua WU ; Zhaoxin QIAN
Chinese Journal of Infection Control 2025;24(8):1027-1032
The aging trend is intensifying currently,but there is still a lack of standardized diagnosis and treat-ment schemes for severe infections in elderly people.This paper focuses on the recommendations for immune-related clinical diagnosis and treatment routes as well as the idea of risk stratified diagnosis and treatment for elderly peo-ple,aiming to effectively prevent infectious diseases in elderly people and perform stratified management through systematic and scientific means of immune function monitoring and regulation,so as to enhance the standardized level of diagnosis and treatment as well as clinical treatment effect of infection in elderly people.
7.Prevalence trends of hospital-associated infections and variation of pathogens in a three-A children's hospital from 2020 to 2024
Liping DU ; Fulai ZHANG ; Nan GAO ; Chunai ZHANG ; Liyuan FU
Chinese Journal of Nosocomiology 2025;35(22):3426-3430
OBJECTIVE To understand the surveillance data regarding to prevalence of hospital-associated infections(HAIs)in a three-A children's specialized hospital of Henan Province and analyze the change trends so as to pro-vide bases for developing precise prevention strategies and optimizing the allocation of infection control resources.METHODS The data involving the case information,case-time infection rates,infection sites,distribu-tion of departments and pathogens were collected from the children who were hospitalized in Children's Hospital Affiliated to Zhengzhou University from 2020 to 2024.The statistical analysis was performed by SPSS 25.0 soft-ware.RESULTS A total of 460,516 children who were hospitalized for treatment from 2020 to 2024,3700 of whom had hospital-associated infections,with the incidence of HAIs 0.80%;totally 3907 case-times of children had HAIs,with the case-time infection rate 0.85%.The departments ranking the top 5 incidence rates of HAIs were as follows:hematopoietic stem cell transplantation ward,ward 2 of hemooncology department,ward 1 of hemooncology department,ward of rehabilitation center,neonatal surgery department.The lower respiratory tract was the major infection site,accounting for 41.13%.The children who had respiratory system infections accounted for 65.29%.The gram-negative bacteria were dominant among the pathogens causing the HAIs,accounting for 48.15%;the percentage of viruses showed an upward trend.CONCLUSIONS The incidence of HAIs shows fluctu-ating downward trend.It is necessary to further strengthen the refined management and take targeted infection prevention and control measures for the departments at high risk of HAIs and the high-risk links so as to continu-ously improve the medical quality and safety.
8.Building a "six-in-one" community cough and asthma center under a "dual-contract physician" model: a preliminary evaluation
Jianling SONG ; Yunfeng ZHANG ; Shuping ZHENG ; Zheng YE ; Xiaopan LI ; Ben FENG ; Leiming GE ; Yao LIU ; Qihao YAN ; Jiani WANG ; Fulai SHEN ; Sunfang JIANG
Chinese Journal of General Practitioners 2025;24(11):1429-1433
This report evaluates the preliminary outcomes of a "six-in-one" integrated cough and asthma center developed under a dual-contract physician model at the Changfeng Community Health Service Center in Putuo District, Shanghai. By combining the efforts of family doctors and medical specialists, the center integrated six core functions-clinical treatment, prevention, nursing, rehabilitation, pharmacy, and nutrition-into a seamless management system covering screening, diagnosis, therapy, and follow-up. Supported by specialist guidance and teaching clinics, the model significantly enhanced comprehensive respiratory disease management capabilities within the community setting. The initiative not only improved patient health outcomes but also strengthened multidisciplinary collaboration and resource efficiency, offering a replicable example for improving chronic disease management in primary care through integrated and coordinated service delivery.
9.Non-invasive detection model for hemoglobin concentration based on support vector regression
Fulai PENG ; Yuanyuan SHUI ; Ningling ZHANG ; Cai CHEN ; Weidong WANG
Chinese Journal of Medical Physics 2024;41(5):594-599
To achieve non-invasive detection of hemoglobin concentration,a hemoglobin concentration detection method based on support vector regression is designed.A mathematical model for non-invasive hemoglobin detection is established based on the Beer-Lambert law.After removing the noise and baseline drift from the collected photoplethysmography signals,hemoglobin concentration information is extracted,and a recursive feature elimination algorithm is used to select the extracted information and eliminate redundant features.Finally,29 key features are identified as input to construct a hemoglobin prediction model using support vector regression algorithm.Experimental validation is conducted on 249 clinical data samples(199 cases in training dataset and 50 in test dataset),resulting in a root mean square error of 1.83 g/dL between predicted values and references,with a correlation coefficient of 0.75(P<0.01),demonstrating the high consistency of the proposed method and traditional invasive detection methods.
10.Effectiveness of family intervention for self-management and glycaemic control in patients with type 2 diabetes: a Meta-analysis and systematic review
Lan ZHU ; Xueying RU ; Zhigang PAN ; Fulai SHEN ; Wei ZHANG ; Yu FENG
Chinese Journal of General Practitioners 2024;23(10):1061-1068
Objective:To evaluate the effect of family intervention on self-management and glycaemic control in patients with type 2 diabetes mellitus (T2DM).Methods:Clinical interventional trials on the family intervention for T2DM patients were searched in PubMed, Medline, Embase, Cochrance libraries, the CNKI, and the Wan Fang Database from January 2016 to June 2023. Literature was screened according to the inclusion and exclusion criteria. Self-management behavior, BMI and glycated haemoglobin of T2DM patients were used as outcome indicators. Meta-analysis and mapping were performed using Review Manager 5.3 software. A systematic review of the literature on indicators of self-management behavior measured using other instruments except Summary of Diabetes Self-Care Activities.Results:A total of 1 342 relevant papers were retrieved and 13 papers were included in the analysis, involving 1 454 patients, 740 in the intervention group and 714 in the control group. Meta-analysis showed that the inclusion of home-based intervention helped adult T2DM patients to improve self-management ( WMD=5.03, 95% CI:4.43-5.63, P<0.001) and reduce glycated hemoglobin compared with the hospital-patient dichotomous model ( WMD=-0.77, 95% CI:-1.32--0.21, P=0.007), but the effect on BMI was unclear ( WMD=-0.38, 95% CI:-1.04-0.28, P=0.25). The results of the systematic review supported that home-based intervention improving self-management behaviors of adult T2DM patients. Conclusion:Family intervention can improve self-management behaviors and reduce glycated haemoglobin levels in adults T2DM patients.

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