Objective To identify the potential categories and influencing factors of apathy in stroke patients,providing a basis for precise typing and individualized interventions by healthcare professionals.Methods Using the convenience sampling method,stroke patients from 2 tertiary hospitals in Xinjiang Uggur Automous Region were selected from November 2023 to August 2024,and were surveyed using the General Information Questionnaire,Apathy Evaluation Scale-Informant,Perceived Autonomy Scale,and Stroke Self-Efficacy Questionnaire.The latent profile analysis was used to identify potential categories of apathy,and logistic regression analysis was used to explore the differences in the characteristics of patients in different categories.Results The apathy symptoms of 521 stroke patients could be divided into 3 potential categories:mild apathy group(23.6％),moderate apathy-low interest-low behavioral group(46.5％),and heavy apathy-low interest-low cognitive group(29.9％).Logistic regression showed that age 45～＜60 years,duration of the disease＜6 months,and high rehabilitation self-efficacy were the common protective factors of the moderate apathy-low interest-low behavioral group and the heavy apathy-low interest-low cognitive group.The dependence on activities of daily living was a risk factor for the moderate apathy-low interest-low behavioral group,and high perception of autonomy was a protective factor for the heavy apathy-low interest-low cognitive group.Conclusion Apathy symptoms in stroke patients are characterized by distinct categories,which are influenced by age,stroke duration,ADL,rehabilitation self-efficacy,and perception of autonomy.Healthcare professionals should adopt effective strategies to precisely intervene based on different potential categories of protective factors and risk factors to alleviate their apathy.

Yttrium-90(90Y)selective internal radiation therapy(SIRT)is an emerging modality for the treatment of hepatocellular carcinoma(HCC),leveraging the nuclide 90Y to deliver targeted radiation therapy.90Y has a long half-life and can be used to selectively ablate tumor cells by high-energy beta rays.It has high biological effectiveness and robust local control capabilities.In recent years,with the continuous advancement of basic and clinical research,the application of 90Y-SIRT in the conversion treatment of unresectable HCC(uHCC)has made significant progress.However,challenges remain in the clinical application of 90Y-SIRT,including how to improve the efficacy of conversion therapy and how to optimize therapy regimens.This review aims to summarize the research progress of90Y-SIRT in the conversion therapy of uHCC.

The morphological characteristics of hepatocellular carcinoma(HCC)tumor margins are pivotal in influencing patient's prognosis and the selection of therapeutic strategies.This paper re-viewed the classification methods of HCC tumor margins,ranging from traditional macroscopic classifi-cations to refined classification systems based on multi-omics analysis,and analyzed the role of these classification methods in guiding the formulation of personalized treatment plans.Additionally,this paper emphasized the crucial role of three-dimensional imaging techniques in assessing tumor margin morphology and outlined future research directions,including validating the effectiveness of multi-omics classification systems and developing new imaging and molecular biomarkers to achieve more precise treatment plans and prolong patient survival.

Objective:To investigate the current situation of rehabilitation motivation of middle-aged and elderly stroke patients and analyze its influencing factors, so as to provide reference for formulating targeted rehabilitation plans and intervention strategies.Methods:A convenience sampling method was used to select middle-aged and elderly stroke patients from (the First Affiliated Hospital of Shihezi University, the People's Hospital of Shihezi, and the People's Hospital of Xinjiang Uygur Autonomous Region from November 2023 to April 2024 as the study subjects. A cross-sectional survey was conducted using a general information questionnaire, the Motivation in Stroke Patients for Rehabilitation Scale, Perceived Social Support Scale, and and Apathy Evaluation Scale-Informant Version.Results:The 328 middle-aged and elderly stroke patients were ultimately included, including 223 males and 105 females, aged (63.63 ± 12.00) years. The total score of rehabilitation motivation, perceived social support and apathy symptoms of middle-aged and elderly stroke patients was ( 86.14 ± 11.28 ), (63.23 ± 6.31), (43.66 ± 4.63) points. LASSO regression screened 8 factors. Multiple linear regression analysis showed that age, education level, stroke duration, neurological deficits, activities of daily living, perceived social support and apathy symptoms were the influencing factors of rehabilitation motivation in middle-aged and elderly stroke patients ( t values were -6.52 to 7.56, all P<0.05), accounting for 72.6% of the total variation. The importance of random forest was ranked as follows: perceived social support, Activity of Daily Living, education level, stroke course, age, apathy symptoms, and neurological deficit. Conclusions:The rehabilitation motivation of middle-aged and elderly stroke patients is at a medium level. Clinical workers should focus on the rehabilitation motivation of stroke patients with insufficient social support, poor self-care ability and low education level, and regularly evaluate the level of rehabilitation motivation and the subjective initiative of rehabilitation exercise.

Objective:To investigate the current situation of rehabilitation motivation of middle-aged and elderly stroke patients and analyze its influencing factors, so as to provide reference for formulating targeted rehabilitation plans and intervention strategies.Methods:A convenience sampling method was used to select middle-aged and elderly stroke patients from (the First Affiliated Hospital of Shihezi University, the People's Hospital of Shihezi, and the People's Hospital of Xinjiang Uygur Autonomous Region from November 2023 to April 2024 as the study subjects. A cross-sectional survey was conducted using a general information questionnaire, the Motivation in Stroke Patients for Rehabilitation Scale, Perceived Social Support Scale, and and Apathy Evaluation Scale-Informant Version.Results:The 328 middle-aged and elderly stroke patients were ultimately included, including 223 males and 105 females, aged (63.63 ± 12.00) years. The total score of rehabilitation motivation, perceived social support and apathy symptoms of middle-aged and elderly stroke patients was ( 86.14 ± 11.28 ), (63.23 ± 6.31), (43.66 ± 4.63) points. LASSO regression screened 8 factors. Multiple linear regression analysis showed that age, education level, stroke duration, neurological deficits, activities of daily living, perceived social support and apathy symptoms were the influencing factors of rehabilitation motivation in middle-aged and elderly stroke patients ( t values were -6.52 to 7.56, all P<0.05), accounting for 72.6% of the total variation. The importance of random forest was ranked as follows: perceived social support, Activity of Daily Living, education level, stroke course, age, apathy symptoms, and neurological deficit. Conclusions:The rehabilitation motivation of middle-aged and elderly stroke patients is at a medium level. Clinical workers should focus on the rehabilitation motivation of stroke patients with insufficient social support, poor self-care ability and low education level, and regularly evaluate the level of rehabilitation motivation and the subjective initiative of rehabilitation exercise.

Objective To identify the potential categories and influencing factors of apathy in stroke patients,providing a basis for precise typing and individualized interventions by healthcare professionals.Methods Using the convenience sampling method,stroke patients from 2 tertiary hospitals in Xinjiang Uggur Automous Region were selected from November 2023 to August 2024,and were surveyed using the General Information Questionnaire,Apathy Evaluation Scale-Informant,Perceived Autonomy Scale,and Stroke Self-Efficacy Questionnaire.The latent profile analysis was used to identify potential categories of apathy,and logistic regression analysis was used to explore the differences in the characteristics of patients in different categories.Results The apathy symptoms of 521 stroke patients could be divided into 3 potential categories:mild apathy group(23.6％),moderate apathy-low interest-low behavioral group(46.5％),and heavy apathy-low interest-low cognitive group(29.9％).Logistic regression showed that age 45～＜60 years,duration of the disease＜6 months,and high rehabilitation self-efficacy were the common protective factors of the moderate apathy-low interest-low behavioral group and the heavy apathy-low interest-low cognitive group.The dependence on activities of daily living was a risk factor for the moderate apathy-low interest-low behavioral group,and high perception of autonomy was a protective factor for the heavy apathy-low interest-low cognitive group.Conclusion Apathy symptoms in stroke patients are characterized by distinct categories,which are influenced by age,stroke duration,ADL,rehabilitation self-efficacy,and perception of autonomy.Healthcare professionals should adopt effective strategies to precisely intervene based on different potential categories of protective factors and risk factors to alleviate their apathy.

This article summarizes the application status of life-space assessment tools by analyzing the impact of life-space on the aged, and provides a reference for researchers to choose the right assessment tools to promote the application of life-space assessment tools in the aged.