1.Application of nickel-titanium shape memory staples in treatment of multiple metatarsal fractures.
Jie CHEN ; Zhen YIN ; Weibo ZHOU ; Wen TAN ; Fulin ZHOU
Chinese Journal of Reparative and Reconstructive Surgery 2025;39(2):146-150
OBJECTIVE:
To investigate the effectiveness of nickel-titanium shape memory staples in treating multiple metatarsal fractures.
METHODS:
The clinical data of 27 patients with multiple metatarsal fractures who were treated between January 2022 and June 2023 and met the selection criteria were retrospectively analysed. The cohort consisted of 16 males and 11 females, aged 33-65 years (mean, 47.44 years). The causes of injury included heavy object impact in 11 cases, traffic accidents in 9 cases, and crush in 7 cases. Simultaneous fractures of 2, 3, 4, and 5 bones occurred in 6, 6, 4, and 8 cases, respectively, with tarsometatarsal joint injury in 3 cases. Fixation was performed using staples for 16, 22, and 9 fractures in the metatarsal neck, shaft, and the base, respectively, and 5 tarsometatarsal joint injuries. Preoperative soft tissue injuries were identified in 8 cases and classified according to the Tscherne-Oestern closed soft tissue injury classification as type Ⅰ in 5 cases and type Ⅱ in 3 cases. One case of type Ⅱexhibited preoperative skin necrosis. The patients were treated with fixation using nickel-titanium shape memory staples. Complications and fracture healing were documented. At last follow-up, the American Orthopaedic Foot and Ankle Society (AOFAS) forefoot score was used to evaluate the function, and the visual analogue scale (VAS) score was used to evaluate the pain.
RESULTS:
The 27 patients were followed up 9-19 months (mean, 12.4 months). Postoperative X-ray films revealed no loss of fracture reduction, and all fractures achieved bony union. No internal fixator loosening, breakage, or other mechanical failures was observed. The mean fracture healing time was 3.13 months (range, 3-4 months). Postoperatively, 4 cases (2 of Tscherne-Oestern type Ⅰ, 2 of type Ⅱ) developed superficial skin necrosis, which resolved with dressing changes. No infection was observed in the remaining patients, and all wounds healed. At last follow-up, the AOFAS forefoot score ranged from 70 to 95, with an average of 86.6, of which 19 cases were excellent, 6 cases were good, and 2 cases were fair, with an excellent and good rate of 92.6%; the VAS score ranged from 0 to 3, with an average of 0.9, of which 24 cases were excellent, and 3 cases were good, with an excellent and good rate of 100%.
CONCLUSION
The use of nickel-titanium shape memory staples in the treatment of multiple metatarsal fractures can effectively protect local skin and soft tissues and minimize secondary damage associated with internal fixator insertion. It is a viable surgical option for management of multiple metatarsal fractures.
Humans
;
Male
;
Female
;
Middle Aged
;
Adult
;
Titanium
;
Nickel
;
Retrospective Studies
;
Fracture Fixation, Internal/instrumentation*
;
Aged
;
Metatarsal Bones/surgery*
;
Fractures, Bone/surgery*
;
Treatment Outcome
;
Sutures
;
Fractures, Multiple/surgery*
2.Comparative study of the effects of intramedullary nail fixation and minimally invasive percutaneous plate internal fixation technique on platelet activation and serum transforming growth factor-β1(TGF-β) 1 and bone morphogenetic protein-2 (BMP-2) in patients with tibial and fibular fracture.
Cheng WEN ; Xi-Jie WANG ; Jun-Cheng HAN ; Han-Wei WANG
China Journal of Orthopaedics and Traumatology 2023;36(11):1100-1106
OBJECTIVE:
To investigate the effect of intramedullary nail fixation (IMN) and minimally invasive percutaneous plate internal fixation (MIPPO) techniques on tibiofibular fractures and their effect on platelet activation and serum transforming growth factor-β1 (TGF-β1) and bone morphogenetic protein-2 (BMP-2).
METHODS:
Total of 105 patients with tibiofibular fractures from February 2019 to February 2020 were selected and divided into 53 cases in the MIPPO group and 52 cases in the IMN group. There were 29 males and 24 females with an average age of (41.74±6.05) years old in MIPPO group;in IMN group, 31 males and 21 females with an average age of (40.59±5.26) years old. The perioperative surgical indexes, postoperative complications, ankle function recovery at 12 months postoperatively, platelet activation indexes at 3 and 7 days preoperatively and postoperatively, and serum TGF-β1 and BMP-2 levels at 4 and 8 weeks preoperatively and postoperatively were compared between the two groups.
RESULTS:
The operating time and fracture healing time in the MIPPO group were shorter than those in the IMN group(P<0.05); Compared with the preoperative period, the levels of GMP-140, PAC-1, CD63, and CD61 increased in both groups at 3 and 7 days after surgery, but were lower in the MIPPO group than in the IMN group(P<0.05);the levels of serum TGF-β1 and BMP-2 increased in both groups at 4 and 8 weeks after surgery compared with the preoperative period, and the postoperative complication rate in the MIPPO group was lower than that in the IMN group(P<0.05);the difference was not statistically significant in the excellent rate of ankle function recovery at 12 months follow-up after surgery between two groups(P>0.05).
CONCLUSION
Both intramedullary nail fixation and MIPO technique for treatment of tibia and fibula fractures can improve ankle joint function, but the latter has the advantages of short operation time, fast fracture healing, fewer complications, and light platelet activation. Serum TGF-β1, BMP-2 level improves quickly.
Male
;
Female
;
Humans
;
Adult
;
Middle Aged
;
Tibia/injuries*
;
Transforming Growth Factor beta1
;
Fracture Fixation, Intramedullary/methods*
;
Tibial Fractures/surgery*
;
Fracture Fixation, Internal/methods*
;
Bone Plates
;
Fracture Healing
;
Postoperative Complications
;
Fractures, Multiple
;
Treatment Outcome
;
Bone Morphogenetic Proteins
;
Minimally Invasive Surgical Procedures/methods*
;
Retrospective Studies
4.Analysis of early treatment of multiple injuries combined with severe pelvic fracture.
Guang-Bin HUANG ; Ping HU ; Jin-Mou GAO ; Xi LIN
Chinese Journal of Traumatology 2019;22(3):129-133
PURPOSE:
To summarize and analyze the early treatment of multiple injuries combined with severe pelvic fractures, especially focus on the hemostasis methods for severe pelvic fractures, so as to improve the successful rate of rescue for the fatal hemorrhagic shock caused by pelvic fractures.
METHODS:
A retrospective analysis was conducted in 68 cases of multiple trauma combined with severe pelvic fractures in recent 10 years (from Jan. 2006 to Dec. 2015). There were 57 males and 11 females. Their age ranged from 19 to 75 years, averaging 42 years. Causes of injury included traffic accidents in 34 cases (2 cases of truck rolling), high falling injuries in 17 cases, crashing injuries in 15 cases, steel cable wound in 1 case, and seat belt traction injury in 1 case. There were 31 cases of head injury, 11 cases of chest injury, 56 cases of abdominal and pelvic injuries, and 37 cases of spinal and limb injuries. Therapeutic methods included early anti-shock measures, surgical hemostasis based on internal iliac artery devasculization for pelvic hemorrhage, and early treatment for combined organ damage and complications included embolization and repair of the liver, spleen and kidney, splenectomy, nephrectomy, intestinal resection, colostomy, bladder ostomy, and urethral repair, etc. Patients in this series received blood transfusion volume of 1200-10,000 mL, with an average volume of 2850 mL. Postoperative follow-up ranged from 6 months to 1.5 years.
RESULTS:
The average score of ISS in this series was 38.6 points. 49 cases were successfully treated and the total survival rate was 72.1%. Totally 19 patients died (average ISS score 42.4), including 6 cases of hemorrhagic shock, 8 cases of brain injury, 1 case of cardiac injury, 2 cases of pulmonary infection, 1 case of pulmonary embolism, and 1 case of multiple organ failure. Postoperative complications included 1 case of urethral stricture (after secondary repair), 1 case of sexual dysfunction (combined with urethral rupture), 1 case of lower limb amputation (femoral artery thrombosis), and 18 cases of consumptive coagulopathy.
CONCLUSION
The early treatment of multiple injuries combined with severe pelvic fractures should focus on pelvic hemostasis. Massive bleeding-induced hemorrhagic shock is one of the main causes of poor prognosis. The technique of internal iliac artery devasculization including ligation and embolization can be used as an effective measure to stop or reduce bleeding. Consumptive coagulopathy is difficult to deal with, which should be detected and treated as soon as possible after surgical measures have been performed. The effect of using recombinant factor VII in treating consumptive coagulopathy is satisfactory.
Adult
;
Embolization, Therapeutic
;
methods
;
Factor VII
;
administration & dosage
;
Female
;
Fractures, Bone
;
complications
;
therapy
;
Hemostasis, Surgical
;
Humans
;
Iliac Artery
;
surgery
;
Injury Severity Score
;
Ligation
;
Male
;
Middle Aged
;
Multiple Trauma
;
complications
;
therapy
;
Pelvic Bones
;
injuries
;
Prognosis
;
Recombinant Proteins
;
administration & dosage
;
Retrospective Studies
;
Shock, Hemorrhagic
;
etiology
;
prevention & control
;
Young Adult
5.Arrival of Fungus in Singapore: Report of the First 3 Cases.
Annals of the Academy of Medicine, Singapore 2018;47(7):260-262
Adult
;
Aged
;
Antifungal Agents
;
administration & dosage
;
adverse effects
;
classification
;
Candida
;
drug effects
;
isolation & purification
;
Carcinoma
;
pathology
;
therapy
;
Cross Infection
;
microbiology
;
therapy
;
Drug Resistance, Multiple, Fungal
;
Female
;
Fractures, Bone
;
surgery
;
Humans
;
Male
;
Middle Aged
;
Mycoses
;
microbiology
;
therapy
;
Patient Care Management
;
methods
;
Pulmonary Disease, Chronic Obstructive
;
complications
;
therapy
;
Surgical Wound Infection
;
microbiology
;
therapy
;
Symptom Flare Up
;
Treatment Outcome
6.Usefulness of indirect open reduction via a transconjunctival approach for the treatment of nasal bone fracture associated with orbital blowout fracture.
Tae Ho KIM ; Seok Joo KANG ; Seong Pin JEON ; Ji Young YUN ; Hook SUN
Archives of Craniofacial Surgery 2018;19(2):102-107
BACKGROUND: Nasal fracture and orbital blowout fracture often occur concurrently in cases of midface blunt trauma. Generally, these multiple fractures treatment is surgery, and typically, the nasal bone and orbit are operated on separately. However, we have found that utilizing a transconjunctival approach in patients with concurrent nasal bone fracture and orbital blowout fracture is a useful method. METHODS: The participants in the present study included 33 patients who visited the Plastic Surgery outpatient department between March 2014 and March 2017 and underwent surgery for nasal fracture and orbital blowout fracture. We assessed patients’ and doctors’ satisfaction with surgical outcomes after indirect open reduction via a transconjunctival approach for the treatment of nasal bone fracture with associated orbital blowout fracture. RESULTS: According to the satisfaction scores, both patients and doctors were satisfied with transconjunctival approach. CONCLUSION: We presented here that our method enables simultaneous operation of nasal fracture accompanied by orbital blowout fracture, rather than treating the two fractures separately, and it allows precise reduction of the nasal fracture by direct visualization of the fracture site without any additional incisions or difficult surgical techniques. Also, by preventing the use of excessive force during reduction, this method can minimize damage to the nasal mucosa, thereby reducing the incidence of nasal bleeding.
Epistaxis
;
Facial Bones
;
Fractures, Multiple
;
Humans
;
Incidence
;
Methods
;
Nasal Bone*
;
Nasal Mucosa
;
Orbit*
;
Orbital Fractures
;
Outpatients
;
Surgery, Plastic
7.Operative versus non-operative treatment for three- or four-part proximal humeral fractures in elderly patients: a meta-analysis of randomized controlled trials.
Wenbo LI ; Gaoheng DING ; Jun LIU ; Jie SHI ; Chao ZHANG ; Qiuming GAO
Journal of Zhejiang University. Medical sciences 2016;45(6):641-647
To evaluate the efficacy of operative and non-operative treatment for three- or four-part proximal humeral fractures in elderly patients by meta-analysis.The literature search was performed in Cochrance Library, Medline, Embase, SinoMed, CNKI, Wanfang data and CQVIP databases for operative and non-operative treatment of three- or four-part proximal humeral fractures in elderly patients, and searches of conference proceedings were also conducted. The data were extracted and a meta-analysis was performed using RevMan 5.3. The outcome measures included Constants score, pain and incidence rates of AVN, reoperation, osteoarthritis, nonunion.Six randomized controlled trials involving 264 patients were included in the meta-analysis. The differences of Constant scores (=0.47, 95%:-4.35-5.28,=0.85), incidence of ANV (=0.56, 95%:0.25-1.24,=0.15), incidence of osteoarthritis (=0.56, 95%:0.19-1.68,=0.30), incidence of nonunion (=0.43, 95%:0.13-1.43,=0.17) between operative group and non-operative group were not statistically significant. Operative treatment was better in pain score (=1.01, 95%:0.12-1.19,=0.03) and had statistically significant higher reoperative rate (=3.97, 95%:1.45-10.92,=0.007).No evidence support that there is difference in Constant score and incidence rate of ANV, osteoarthritis, nonunion between operative and non-operative treatment for three- or four-part proximal humeral fractures in elderly patients. More high quality randomized controlled trials are required to determine which treatment is more efficient.
Aged
;
Comparative Effectiveness Research
;
Fracture Healing
;
Fractures, Multiple
;
complications
;
therapy
;
Fractures, Ununited
;
epidemiology
;
Humans
;
Humerus
;
injuries
;
surgery
;
Orthopedic Procedures
;
adverse effects
;
methods
;
statistics & numerical data
;
Osteoarthritis
;
epidemiology
;
Osteonecrosis
;
epidemiology
;
Randomized Controlled Trials as Topic
;
Reoperation
;
statistics & numerical data
;
Shoulder Fractures
;
complications
;
therapy
;
Treatment Outcome
8.Early intramedullary nailing for femoral fractures in patients with severe thoracic trauma: A systemic review and meta-analysis.
Xiao-Yuan LIU ; Meng JIANG ; C-L YI ; Xiang-Jun BAI ; David-J HAK
Chinese Journal of Traumatology 2016;19(3):160-163
PURPOSEEarly intramedullary nailing (IMN) within the first 24 h for multiply injured patients with femoral fracture and concomitant thoracic trauma is controversial. Previously published studies have been limited in size and their outcomes have been inconclusive. A meta-analysis was conducted to evaluate the available data in order to guide care and help improve the outcomes for these patients.
METHODSWe searched the literature up to December 2011 in the main medical search engines and identified 6 retrospective cohort studies that explored the safety of early IMN in patients with both femoral fracture and chest injury. Our primary outcome was the rates of pulmonary complication (pneumonia, adult respiratory distress syndrome, fat embolism syndrome), multiple organ failure (MOF) and mortality.
RESULTSWe found no statistically significant difference in the rate of pulmonary complications, MOF or mortality in the patients treated with early IMN.
CONCLUSIONEarly IMN for femoral fractures does not increase the mortality and morbidity in chest- injured patients in the studies analyzed.
Femoral Fractures ; surgery ; Fracture Fixation, Intramedullary ; adverse effects ; methods ; mortality ; Humans ; Multiple Organ Failure ; epidemiology ; Pneumonia ; epidemiology ; Respiratory Distress Syndrome, Adult ; epidemiology ; Thoracic Injuries ; surgery
9.The Floating Upper Limb: Multiple Injuries Involving Ipsilateral, Proximal, Humeral, Supracondylar, and Distal Radial Limb.
Qazi MANAAN ; Adil BASHIR ; Adnan ZAHOOR ; Taseem A MOKHDOMI ; Qazi DANISH
Clinics in Orthopedic Surgery 2016;8(3):345-348
Floating arm injury represents a common yet complicated injury of the childhood severely associated with limb deformation and even morbidity, if not precisely addressed and credibly operated. Here, we report a rare floating upper limb case of a 9-year-old boy with multiple injuries of ipsilateral proximal humeral, supracondylar and distal radial limb. This is the first report to document such a combined floating elbow and floating arm injury in the same limb. In this report, we discuss the surgical procedures used and recovery of the patient monitored to ascertain the effectiveness of the method in limb reorganisation.
Accidental Falls
;
*Bone Wires
;
Child
;
Fracture Fixation
;
Humans
;
*Humeral Fractures
;
Male
;
Multiple Trauma
;
Radiography
;
*Radius Fractures
;
*Upper Extremity/diagnostic imaging/injuries/surgery
10.Damage control resuscitation of severe multiple trauma in the pelvic fractures.
China Journal of Orthopaedics and Traumatology 2015;28(5):399-403
OBJECTIVETo discuss the clinical effects of damage control resuscitation (DCR) in treating severe multiple trauma in the pelvic fractures.
METHODSFrom March 2009 to September 2013, a restrospective analysis was conducted on the clinical data of 28 patients with multiple trauma in the pelvic fractures, including 19 males and 9 females, ranging in age from 21 to 51 years old with an average of 32.5 years old. According to Tile classification of pelvic fractures, 16 cases were type B and 12 cases were type C. Injury severity score (ISS) averaged 32.0±3.4. All cases were treated with damage contral orthopaedics and DCR strategy, namely that used immediately with small capacity of balanced salt solution on admission so as to maintain the blood pressure between 80 to 90 mmHg. At the same time, emergency phase I simple debridement plus external fixator or bundled with fixed pelvic was done, and the chest or abdomen combined injury was treated at first. And limbs fracture was temporary dealing with bone traction or plaster external fixation, etc. After bleeding was controlled by operation, fluid resuscitation was done as fast as possible and the plasma was transfused early according to the proportion of plasma and red cell suspension (2 U:1 U-3 U:2 U). Dosage of balanced salt solution and blood before remedy shock was recorded, and the removal of time of lactic acid and coagulation were observed.
RESULTSFive cases were died after 4 to 15 hours into hospital (3 cases died for severe trauma-hemorrhagic shock and 2 cases for acute respiratory distress syndrome). Twenty-three cases were remedy shock at 1.6 to 4.3 hours after injury with an average of 2.4 hours. Period I operation duration was (78.2±10.3) minutes. Dosage of balanced salt solution was (3,798±340) ml and red cell suspension was 14 to 18 U, fresh frozen plasma (FFP) was (1,267±58) ml (1U FFP=100 ml), blood platelet was 8 to 12 U for 9 patients. The removal time of lactic acid and PT-APTT was (11.4±2.1) hours and (4.3±0.8) hours. Measures were taken to correct electrolyte and acid-base imbalance was normal. The success rat of recovery was 82.2% (23/28).
CONCLUSIONDamage control resuscitation (DCR) integrates the main links such as damage control operation and allowable low blood pressure (or limited liquid resuscitation) and hemostatic control resuscitation, was early effective treatment measures for the patients with severe multiple trauma in the pelvic fractures.
Adult ; Female ; Fractures, Bone ; surgery ; Humans ; Male ; Middle Aged ; Multiple Trauma ; surgery ; Pelvic Bones ; injuries ; surgery ; Resuscitation ; Retrospective Studies ; Treatment Outcome ; Young Adult

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