6.Animal DNA Typing and Its Research Progress in Forensic Medicine.
Hong-Yan GAO ; Guang-Fu LIU ; Jian WU ; Peng-Yu CHEN
Journal of Forensic Medicine 2023;39(2):161-167
With the advance of molecular biology, DNA analysis technology has been widely applied in forensic science. Non-human DNA analysis can be used in some special cases and has unique forensic value to provide investigation clues and trial basis. Animal DNA typing plays a more prominent role in the detection of all kinds of non-human DNA related cases and is the main content of forensic non-human DNA analysis. This paper reviews the development history, present situation, advantages and disadvantages of animal DNA typing according to its technology, characteristic, challenges facing forensic science application scenarios, and also its future development.
Animals
;
DNA Fingerprinting
;
Forensic Medicine
;
DNA/analysis*
;
Forensic Sciences
;
Molecular Biology
;
Forensic Genetics
7.Progress in the Application of Magnetic Nanoparticles in Forensic Trace Analysis.
Zhong-Ping CHENG ; Yan-Fei LIU ; Xing-Min XU ; Yao-Nan MO
Journal of Forensic Medicine 2023;39(2):168-175
Given the complexity of biological samples and the trace nature of target materials in forensic trace analysis, a simple and effective method is needed to obtain sufficient target materials from complex substrates. Magnetic nanoparticles (MNPs) have shown a wide range of application value in many research fields, such as biomedicine, drug delivery and separation, due to their unique superparamagnetic properties, stable physical and chemical properties, biocompatibility, small size, high specific surface area and other characteristics. To apply MNPs in the pretreatment of forensic materials, maximize the extraction rate of the target materials, and minimize interference factors to meet the requirements of trace analysis of the target materials, this paper reviews the application of MNPs in the fields of forensic toxicological analysis, environmental forensic science, trace evidence analysis and criminal investigation in recent years, and provides research ideas for the application of MNPs in forensic trace analysis.
Magnetite Nanoparticles/chemistry*
;
Forensic Medicine
;
Forensic Sciences
;
Forensic Toxicology
8.Survey on the Construction Status of Forensic Virtual Autopsy Laboratory and the Applicability of Laboratory Accreditation.
Jun-Wei GAO ; Yang LU ; Yan-Jun LI ; Dong-Hua ZOU ; Guang-Long HE ; Yan-Bin WANG
Journal of Forensic Medicine 2023;39(2):186-192
OBJECTIVES:
To survey the development status and actual needs of virtual autopsy technology in China and to clarify the applicability of forensic virtual autopsy laboratory accreditation.
METHODS:
The questionnaire was set up included three aspects:(1) the current status of virtual autopsy technology development; (2) the accreditation elements such as personnel, equipment, entrustment and acceptance, methods, environmental facilities; (3) the needs and suggestions of practicing institutions. A total of 130 forensic pathology institutions were surveyed by online participation through the Questionnaire Star platform.
RESULTS:
Among the 130 institutions, 43.08% were familiar with the characteristics of virtual autopsy technology, 35.38% conducted or received training in virtual autopsy, and 70.77% have establishment needs (including maintenance). Relevant elements were suitable for laboratory accreditation.
CONCLUSIONS
Virtual autopsy identification has gained social recognition. There is a demand for accreditation of forensic virtual autopsy laboratory. After the preliminary assessment, considering the characteristics and current situation of this technology, China National Accreditation Service for Conformity Assessment (CNAS) can first carry out the accreditation pilot of virtual autopsy project at large comprehensive forensic institutions with higher identification capability, and then CNAS can popularize the accreditation in a wide range when the conditions are suitable.
Autopsy
;
Forensic Medicine
;
Forensic Pathology
;
Accreditation
;
Surveys and Questionnaires
9.Exploration and Practice of the "One Combination, Two Highlights, Three Combinations, Four in One" Innovative Talents Training Mode in Forensic Medicine.
Jiang-Wei YAN ; Jun-Hong SUN ; Hong-Xing WANG ; Zhi-Wen WEI ; Xiang-Jie GUO ; Ji LI ; Cai-Rong GAO ; Geng-Qian ZHANG ; Xin-Hua LIANG ; Qiang-Qiang ZHANG ; Hong-Wei WANG ; Si-Jin LI ; Ying-Yuan WANG ; Ke-Ming YUN
Journal of Forensic Medicine 2023;39(2):193-199
Talent is one of the basic and strategic supports for building a modern socialist country in all aspects. Since the 1980s, the establishment of forensic medicine major and the cultivation of innovative talents in forensic medicine have become hot topics in higher education in forensic medicine. Over the past 43 years, the forensic medicine team of Shanxi Medical University has adhered to the joint education of public security and colleges, and made collaborative innovation, forming a training mode of "One Combination, Two Highlights, Three Combinations, Four in One" for innovative talents in forensic medicine. It has carried out "5+3/X" integrated reform, and formed a relatively complete talent training innovation mode and management system in teaching, scientific research, identification, major, discipline, team, platform and cultural construction. It has made a historic contribution to China's higher forensic education, accumulated valuable experience for the construction of first-class major and first-class discipline of forensic medicine, and provided strong support for the construction of the national new forensic talent training system. The popularization of this training mode is conducive to the rapid and sustainable development of forensic science, and provides more excellent forensic talents for national building, regional social development and the discipline construction of forensic science.
Humans
;
Forensic Medicine/education*
;
Aptitude
10.Research Progresses of Tri-Allelic Patterns in Autosomal STR in Forensic DNA Analysis.
Xiao-Yan MA ; Hong-Yu SUN ; Qing LI
Journal of Forensic Medicine 2023;39(3):240-246
Tri-allelic pattern in autosomal STR is a common abnormal typing phenomenon in forensic DNA analysis, which brings difficulties and uncertainties to the evaluation of the evidence weight in actual cases. This paper reviews the types, formation mechanism, occurrence frequency, genetic pattern and quantitative evaluation of evidence of the tri-allelic pattern in autosomal STR in forensic DNA analysis. This paper mainly explains the formation mechanism and genetic patterns based on different types of tri-allelic pattern. This paper also discusses the determination of tri-allelic pattern and the quantitative method of evidence evaluation in paternity testing and individual identification. This paper aims to provide references for scientific and standardized analysis of this abnormal typing phenomenon in forensic DNA analysis.
Alleles
;
DNA/genetics*
;
Forensic Medicine
;
Gene Frequency
;
Microsatellite Repeats
;
Humans

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