Objective:To investigate the efficacy of the ABC-X model-based nursing in patients with vitiligo undergoing autologous cell-spray grafting of non-cultured epidermal cells (Recell technique) .Methods:A total of 84 vitiligo patients treated with ReCell technique admitted to the Department of Dermatology of the First Affiliated Hospital of Zhengzhou University from February 2022 to February 2024 were selected for the study using the convenience sampling method. The patients were divided into observation group (42 cases) and control group (42 cases) according to randomized numerical table method. Control group received conventional nursing, and observation group was treated with ABC-X model-based nursing on the basis of control group. The Self-rating Anxiety Scale (SAS), Self-rating Depression Scale (SDS), Trait Coping Style Questionnaire (TCSQ), and Dermatology Life Quality Index (DLQI) scores were compared between the two groups before and after the intervention.Results:After the intervention, the SAS and SDS scores of observation group were lower than those of control group, and the differences were statistically significant (all P<0.05). After the intervention, the positive coping score in TCSQ of observation group was higher than that of control group, and the negative coping score was lower than that of control group, and the differences were all statistically significant (all P<0.05). After the intervention, the total DLQI score of observation group was lower than that of control group, and the difference was statistically significant ( P<0.05) . Conclusions:The nursing based on ABC-X model in vitiligo patients treated with ReCell technique can improve patients' psychological conditions, promote positive coping, and enhance the quality of life, which is worthy of popularization and application.

Objective:To investigate the efficacy of the ABC-X model-based nursing in patients with vitiligo undergoing autologous cell-spray grafting of non-cultured epidermal cells (Recell technique) .Methods:A total of 84 vitiligo patients treated with ReCell technique admitted to the Department of Dermatology of the First Affiliated Hospital of Zhengzhou University from February 2022 to February 2024 were selected for the study using the convenience sampling method. The patients were divided into observation group (42 cases) and control group (42 cases) according to randomized numerical table method. Control group received conventional nursing, and observation group was treated with ABC-X model-based nursing on the basis of control group. The Self-rating Anxiety Scale (SAS), Self-rating Depression Scale (SDS), Trait Coping Style Questionnaire (TCSQ), and Dermatology Life Quality Index (DLQI) scores were compared between the two groups before and after the intervention.Results:After the intervention, the SAS and SDS scores of observation group were lower than those of control group, and the differences were statistically significant (all P<0.05). After the intervention, the positive coping score in TCSQ of observation group was higher than that of control group, and the negative coping score was lower than that of control group, and the differences were all statistically significant (all P<0.05). After the intervention, the total DLQI score of observation group was lower than that of control group, and the difference was statistically significant ( P<0.05) . Conclusions:The nursing based on ABC-X model in vitiligo patients treated with ReCell technique can improve patients' psychological conditions, promote positive coping, and enhance the quality of life, which is worthy of popularization and application.

Objective:To establish the rat cardiac arrest model in high-altitude hypobaric hypoxia environment, and to explore the effect of the treatment time in the hypobaric oxygen chamber on the reproduction of high-altitude rat cardiac arrest model.Methods:SPF grade healthy male Sprague-Dawley (SD) rats were used as observation subjects. The experiment was conducted in two different altitude areas. The rats from the Plateau Branch of Institute of Cardiopulmonary and Cerebral Resuscitation of Sun Yat-sen University (Xining, Qinghai) were weighed and numbered, and they were placed in a hypobaric oxygen chamber (simulated altitude of 3 000 meters, speed of ascent and descent of 15 m/min, temperature of 20 ℃, cabin pressure of 69.5 kPa, cabin oxygen pressure of 14.5 kPa). After 30 days of feeding, the rats were obtained according to random number table method, and the cardiac arrest model was established by asphyxia method as the 30-day hypobaric hypoxia group. After 60 days of feeding, rats were randomly selected again, and the cardiac arrest model was established as the 60-day hypobaric hypoxia group. Thirty rats were randomly selected from the Institute of Cardiopulmonary Cerebral Resuscitation at Sun Yat-sen University (Guangzhou, Guangdong) by the same method, and the cardiac arrest model was established as the plain control group. The differences in the body weight of rat modeling precursors and the induction time of asphyxia during the modeling process among different groups were compared.Results:Finally, cardiac arrest model was established in 16 rats in the 30-day hypobaric hypoxia group and in 22 rats in the 60-day hypobaric hypoxia group. There was no significant difference in the body weight of rats before modeling among the plain control group, 30-day hypobaric hypoxia group and 60-day hypobaric hypoxia group [g: 429.00 (389.25, 440.75), 440.00 (415.50, 486.25), 440.00 (400.00, 452.50), all P > 0.05]. The asphyxia induction time of rats in the 60-day hypobaric hypoxia group was significantly longer than that in the 30-day hypobaric hypoxia group (s: 294.59±75.39 vs. 234.31±93.86, P < 0.01), even about 1.4 times of the plain control group (s: 294.59±75.39 vs. 208.73±30.88, P < 0.01). There was no significant difference in the asphyxia induction time between the 30-day hypobaric hypoxia group and the plain control group ( P > 0.05). Conclusion:Rats treated in a hypobaric oxygen chamber for 60 days are more suitable for the preparation of high-altitude cardiac arrest model, and are also consistent with the oxygen reserve and hypoxia tolerance of high-altitude rats.

Morita therapy has been bom for more than 100 years.Inpatient Morita therapy is highly oper-able and easy to master.It can improve many refractory neuroses through four-stage treatment.But more neuroses are treated in outpatient clinics,and Morita therapy cannot be used in hospitalized patients.Therefore,the formula-tion of expert opinions on outpatient operations is particularly important.This paper is based on domestic and for-eign references,and after many discussions by domestic Morita therapy experts,and then drew up the first version of the expert opinions on operation of outpatient Morita therapy.Meanwhile the operation rule of Morita therapy in three stages of outpatient treatment was formulated:in the etiological analysis stage,under the theoretical guidance of Morita therapy,analyze the pathogenic factors,to improve treatment compliance and reduce resistance;during the operating stage,guide patients to engage in constructive and meaningful actions,realizing the achievement of letting nature take its course principle;in the cultivating character and enriching life stage,pay attention to positive infor-mation,expanding the scope and content of actions,improving the ability to adapt to complex life,and preventing recurrence caused by insufficient abilities.It will lay a foundation for the promotion of Morita therapy in domestic outpatient clinics,so that more patients with neurosis and other psychological diseases could receive characteristic Morita therapy treatment in outpatient clinics.

Objective To investigate the interaction between homocysteine (HCY) and uric acid (UA) on the atherosclerosis (AS) of the fishing crew.Methods Research data were recruited from the special AS survey of 3 671 fishing workers (＞ 35 years old)of 11 large fishing companies,who had health checks from December 2014 to December 2016.Levels of homocysteine (HCY),uric acid (UA),carotid artery intimamedia thickness (CIMT) and carotid femoral pulse wave velocity (cfPWV) were detected in the 3 081 eligible subjects.According to the detected HCY and UA data,they were divided into 4 groups:the HCY and UA normal group (or the control group,n =1 486),the HCY high and UA normal group (or the HHCY group,n =979),the normal HCY and high UA group (or the HUA,n =370) and the increased HCY and UA group (or the HHCY group,n =979).The interaction of AS was assessed with 2 × 2 factorial analysis.Results Compared with those of the control group[(1.23 ±0.30) mm,(10.45 ±0.86) m/s],the levels of CIMT [(1.32±0.28),(1.30±0.30),(1.49 ±0.24) mm] and cfPWV[(10.63±0.99),(10.81 ±1.11),(11.40 ± 1.36) m/s] in the HHCY,HUA and HHCY + HUA groups all significantly elevated,and statistical significance could be seen,when comparisons were made between them (P ＜ 0.05).Compared with those of the HHCY group,the level of cfPWV in the HUA group and the level of CIMT in the HHCY + HUA group were significantly increased (P ＜ 0.05).In comparison with those of the HUA group,the levels of CIMT and cfPWV in the HHCY + HUA group all significantly elevated (P ＜ 0.05).The levels of HCY and UA were positively correlated with the levels of CIMT (r =0.375,r =0.285) and cfPWV (r =-0.342,r =0.399) (P ＜ 0.01).After correction of the confounding factors,HCY and UA were all independent factors of CIMT and cfPWV.The results of the 2 × 2 factorial analysis showed that HCY and UA had significant synergistic effect on IMT and cfPWV (P ＜ 0.01).Conclusions Both HCY and UA were independent influential factors of AS in fishing workers,and at the same time,they displayed synergistic interaction.

Objective To investigate the interaction between homocysteine (HCY) and uric acid (UA) on the atherosclerosis (AS) of the fishing crew.Methods Research data were recruited from the special AS survey of 3 671 fishing workers (＞ 35 years old)of 11 large fishing companies,who had health checks from December 2014 to December 2016.Levels of homocysteine (HCY),uric acid (UA),carotid artery intimamedia thickness (CIMT) and carotid femoral pulse wave velocity (cfPWV) were detected in the 3 081 eligible subjects.According to the detected HCY and UA data,they were divided into 4 groups:the HCY and UA normal group (or the control group,n =1 486),the HCY high and UA normal group (or the HHCY group,n =979),the normal HCY and high UA group (or the HUA,n =370) and the increased HCY and UA group (or the HHCY group,n =979).The interaction of AS was assessed with 2 × 2 factorial analysis.Results Compared with those of the control group[(1.23 ±0.30) mm,(10.45 ±0.86) m/s],the levels of CIMT [(1.32±0.28),(1.30±0.30),(1.49 ±0.24) mm] and cfPWV[(10.63±0.99),(10.81 ±1.11),(11.40 ± 1.36) m/s] in the HHCY,HUA and HHCY + HUA groups all significantly elevated,and statistical significance could be seen,when comparisons were made between them (P ＜ 0.05).Compared with those of the HHCY group,the level of cfPWV in the HUA group and the level of CIMT in the HHCY + HUA group were significantly increased (P ＜ 0.05).In comparison with those of the HUA group,the levels of CIMT and cfPWV in the HHCY + HUA group all significantly elevated (P ＜ 0.05).The levels of HCY and UA were positively correlated with the levels of CIMT (r =0.375,r =0.285) and cfPWV (r =-0.342,r =0.399) (P ＜ 0.01).After correction of the confounding factors,HCY and UA were all independent factors of CIMT and cfPWV.The results of the 2 × 2 factorial analysis showed that HCY and UA had significant synergistic effect on IMT and cfPWV (P ＜ 0.01).Conclusions Both HCY and UA were independent influential factors of AS in fishing workers,and at the same time,they displayed synergistic interaction.

Objective To analyze the risk factors of unplanned pregnancy after artificial abortion. Methods 4 000 patients after artifi-cial abortion in our hospital from May 2010 to May 2013 were selected for this study. 1 723 patients who conducted unplanned pregnancy after artificial abortion were observation group,then 1 723 patients were selected randomly in patients without unplanned pregnancy after artificial abortion as control group. The number of the age under 19,rural registered permanent residence,income below 2 000 yuan,high school diplo-ma or less,domestic partnership,2 or more sex partners and first sexual behavior under 17 were observed. Results In the 4 000 patients, the rate of unplanned pregnancy after artificial abortion was 43. 08%. Chi-square test and logistics regression analysis revealed that age under 19,rural registered permanent residence,income below 2 000 yuan,high school diploma or less, domestic partnership,2 or more sex partners and first sexual behavior under 17 were the risk factors of unplanned pregnancy after artificial abortion. Conclusion Young age,low educa-tion level,low income and open-minded about sex are the key risk factors of unplanned pregnancy after artificial abortion.