Objective To analyze the projects of the Management Science Department of the National Natural Science Foundation of China(NSFC)funded to hospital pharmacists from 2013 to 2024,providing references for hospital pharmacists to apply for such projects.Methods Websites such as the National Natural Science Foundation Big Data Knowledge Service Management Portal,MedSci,and LetPub were retrieved,supplemented by manual retrieval.Relevant projects with hospital pharmacists as the project leaders were screened out,and keywords such as the research topic,research theory/model,and research type of the projects were extracted for analysis.Results From 2013 to 2024,40 projects of the Management Science Department of the NSFC were given to hospital pharmacists as project leaders,and both the number of projects and the proportion of funding showed an upward trend.The awarded projects mostly demonstrated the relevance of national macro-pharmaceutical policies and were matched with corresponding management theories/models based on the research content.The research themes and research objects were diverse,and the research types were mainly model construction and pattern construction.Conclusion Pharmacists should closely follow the direction of national policies,seek research inspirations in their daily work,and enhance the learning of management research methods,guiding and regulating research through management theories.

Objective To analyze the projects of the Management Science Department of the National Natural Science Foundation of China(NSFC)funded to hospital pharmacists from 2013 to 2024,providing references for hospital pharmacists to apply for such projects.Methods Websites such as the National Natural Science Foundation Big Data Knowledge Service Management Portal,MedSci,and LetPub were retrieved,supplemented by manual retrieval.Relevant projects with hospital pharmacists as the project leaders were screened out,and keywords such as the research topic,research theory/model,and research type of the projects were extracted for analysis.Results From 2013 to 2024,40 projects of the Management Science Department of the NSFC were given to hospital pharmacists as project leaders,and both the number of projects and the proportion of funding showed an upward trend.The awarded projects mostly demonstrated the relevance of national macro-pharmaceutical policies and were matched with corresponding management theories/models based on the research content.The research themes and research objects were diverse,and the research types were mainly model construction and pattern construction.Conclusion Pharmacists should closely follow the direction of national policies,seek research inspirations in their daily work,and enhance the learning of management research methods,guiding and regulating research through management theories.

Objective To explore the early predictors of the development of the novel coronavirus infection(COVID-19)into severe and critical forms.Methods COVID-19 patients hospitalized in the Department of Intensive Care Medicine,Infection ward,Respiratory and Critical Care Medicine of the First Affiliated Hospital of Guangxi Medical University from December 2022 to March 2023 were selected as the study objects,and were divided into mild/medium group,severe group,and critical group according to the severity of illness during hospitalization.General clinical data and early laboratory results of the three groups were collected and compared.Results A total of 242 patients with novel coronavirus infection were included,including 117 mild/medium patients,55 severe patients,and 70 critically severe patients.There were 165 males and 77 females with a median age of 70(59,80)years.The age,sex,diabetes,heart disease,stroke,combined pneumonia,combined bloodstream infection,APACHE Ⅱ score,respiratory rate on admission,systolic blood pressure,and early white blood cell count(WBC),lymphocyte count(LYM),urea,creatinine,albumin,C-reactive protein,D-dimer,interleukin-6(IL-6),and calcium reduction of patients in the three groups had significant(all P<0.05).Ordered logistic regression shows,previous heart disease,stroke,combined bloodstream infection,WBC,high IL-6 level,and low LYM level were independent risk factors for severe and critical COVID-19 infection[odds ratio(OR)and 95%confidence interval(95%CI)were 3.253(1.694～6.246),5.251(2.378～11.592),respectively.6.920(2.499～19.189),1.111(1.041～1.186),1.003(1.001～1.006),0.571(0.353～0.926)].ROC curve analysis showed that WBC,LYM,IL-6 and their combined detection had certain predictive value for the severity of COVID-19(all P<0.05),and the combined detection of WBC,LYM and IL-6 had better predictive value than a single indicator(P<0.05).Conclusion Previous heart disease,cerebrovascular disease,early combination of bloodstream infection,high levels of IL-6,white blood cell count,and low lymphocyte levels at admission were independent risk factors that helped to predict the severity of COVID-19 infection early.The combined detection of WBC,LYM and IL-6 has certain predictive value for the development of severe and critical COVID-19.