Objective To evaluate the safety and efficacy of flow diverter stent(FDS)implantation in treating blood blister-like aneurysms(BBA).Methods The clinical data and imaging findings(including baseline data,aneurysm data,surgical pattern,surgery-related complications and follow-up results)of 14 patients with BBA,who were admitted to West China hospital of Sichuan University from January 2022 to June 2023,were retrospectively analyzed.Results Of the 14 patients with BBA,pipeline embolization device-assisted(PED-assisted)coil embolization was performed in 5,only PED in 3,Tubridge close-mesh stent(TB)-assisted coil embolization in 5,only TB in one.In the 4 patients receiving only FDS,the immediate postoperative angiography showed that retention of contrast agent was seen in the aneurysm,and no aneurysm visualization was seen in the remaining patients.One patient,who received TB-assisted coil embolization,developed postoperative delayed massive cerebral infarction and died.One patient,who received only PED,developed right limb hemiplegia with an mRS score of 2 points at follow-up visit.In the remaining 12 patients,the mRS score was 0 point at the time of discharge as well as at the time of follow-up visit.In 13 patients,follow-up angiography demonstrated that the aneurysm was completely occluded.Conclusion For the treatment of BBA,FDS-assisted coil embolization or single FDS is clinically safe and effective,although there is potential risk of perioperative aneurysm rebleeding and cerebral infarction.