1.Diagnostic value of ultrasound parameters of umbilical artery combined with Hcy and D-dimer in FGR
Yang WANG ; Fanrui MENG ; Ying ZHANG ; Jinhui ZHANG
China Medical Equipment 2025;22(6):59-63
Objective:To explore the diagnostic value of ultrasound parameters of umbilical artery(UA)combined with homocysteine(Hcy)and D-dimer in fetal growth restriction(FGR).Methods:A total of 87 pregnant women with FGR who admitted to Tangshan Maternal and Child Health Care Hospital from June 2020 to June 2023 were included in the FGR group,and 109 normal pregnant women were included in the normal control group during the same period.Color Doppler ultrasound was used to measure UA parameters of fetal in normal control group and FGR group.The serums of pregnant women were collected to detect Hcy and D-dimer levels.The area under curve(AUC)of receiver operating characteristic(ROC)curve was used to analyze the diagnostic value of UA ultrasound parameters,which included pulsation index(PI),resistance index(RI),systolic/diastolic(S/D),combined with Hcy and D-dimer for FGR.Results:The PI,RI,S/D,Hcy and D-dimer levels of UA ultrasound parameters of FGR group were significantly higher than these of normal control group,and the differences were statistically significant(t=6.325,7.380,8.455,5.267,7.686,P<0.05).The ROC analysis indicated that AUC values of PI,RI,S/D,Hcy and D-dimer were respectively 0.742,0.749,0.805,0.702 and 0.792 in alone diagnosing FGR.The AUC value of combined diagnosis was significantly higher than the alone diagnosis of each indicator,and the differences were statistically significant(Z=2.978,0.190,0.128,0.231,0.141,P<0.05).Conclusion:UA ultrasound parameters,Hcy and D-dimer levels show significant changes in FGR,and all of them can be used to screen FGR.The effectiveness of the combined screening is more significant.
2.Diagnostic value of ultrasound parameters of umbilical artery combined with Hcy and D-dimer in FGR
Yang WANG ; Fanrui MENG ; Ying ZHANG ; Jinhui ZHANG
China Medical Equipment 2025;22(6):59-63
Objective:To explore the diagnostic value of ultrasound parameters of umbilical artery(UA)combined with homocysteine(Hcy)and D-dimer in fetal growth restriction(FGR).Methods:A total of 87 pregnant women with FGR who admitted to Tangshan Maternal and Child Health Care Hospital from June 2020 to June 2023 were included in the FGR group,and 109 normal pregnant women were included in the normal control group during the same period.Color Doppler ultrasound was used to measure UA parameters of fetal in normal control group and FGR group.The serums of pregnant women were collected to detect Hcy and D-dimer levels.The area under curve(AUC)of receiver operating characteristic(ROC)curve was used to analyze the diagnostic value of UA ultrasound parameters,which included pulsation index(PI),resistance index(RI),systolic/diastolic(S/D),combined with Hcy and D-dimer for FGR.Results:The PI,RI,S/D,Hcy and D-dimer levels of UA ultrasound parameters of FGR group were significantly higher than these of normal control group,and the differences were statistically significant(t=6.325,7.380,8.455,5.267,7.686,P<0.05).The ROC analysis indicated that AUC values of PI,RI,S/D,Hcy and D-dimer were respectively 0.742,0.749,0.805,0.702 and 0.792 in alone diagnosing FGR.The AUC value of combined diagnosis was significantly higher than the alone diagnosis of each indicator,and the differences were statistically significant(Z=2.978,0.190,0.128,0.231,0.141,P<0.05).Conclusion:UA ultrasound parameters,Hcy and D-dimer levels show significant changes in FGR,and all of them can be used to screen FGR.The effectiveness of the combined screening is more significant.
3.A Survey on the Mental Health Status of Social Workers Under Long-term Stress of COVID-19 and the Exploration of Associated Factors: A Case Study of Chaoyang District, Beijing
Han ZHANG ; Yuan GAO ; Wanxin MA ; Hongxin LIU ; Fanrui MENG ; Danping ZHANG ; Chunyu LIU ; Lu LIU ; Ying XING
Medical Journal of Peking Union Medical College Hospital 2024;15(4):845-854
To study the prevalence of depression, anxiety, and insomnia among social workers during the prolonged battle against the COVID-19 pandemic and explore the associated risk factors. Using a stratified cluster sampling method, we selected all social workers in the five streets of Chaoyang District, Beijing(Jiuxianqiao, Wangjing, Taiyanggong, Shibalidian, Sunhe) from November 2021 to March 2022 as the study population(social worker group), and the frontline medical staffs(medical professional group) of the same age range of the corresponding community hospitals of the same five streets, and the community residents(resident group) as the control population. The ratio of the social worker group, medical professional group, and resident group was 1∶1∶1. The Sojump platform was used to send electronic questionnaires to the wechat groups of social workers, healthcare workers, and community residents to carry out the survey. The screen positive rates for anxiety, depression, and sleep disorders were compared among the 3 groups. Multifactorial Logistic regression and decision tree were used to analyze the influencing factors of anxiety, depression, and sleep disorders among social workers. A total of 954 questionnaires were collected, of which 62 were disqualified and excluded. Finally, 892 valid questionnaires(93.5%) were included for data analysis. Among them, there were 372 questionnaires(41.7%) from the social worker group, 262(29.4%) from the medical professional group, and 258(28.9%) from the resident group. The prevalences of anxiety, depression, and sleep disorders among social workers group were found to be 15.3%, 22.0%, and 48.1%, respectively, which were significantly higher than those in the medical professional group(7.6%, 10.3%, and 30.5%) and the resident group(7.0%, 8.5%, and 29.5%), all Social workers exhibited significant levels of anxiety, depression, and sleep disorders during the long-term pandemic prevention, with CPSS being the most significant influencing factor.
4.Observation on therapeutic effects of acupuncture plus Chinese herbs for sudden deafness
Huanren WANG ; Fanrui MENG ; Xiaowei CHI ; Jian DING
Journal of Acupuncture and Tuina Science 2015;(4):260-264
Objective:To observe the clinical effect of wind-expelling method of acupuncture and Chinese herbs for sudden deafness.
Methods:A total of 90 cases with sudden deafness were randomly divided into three groups based upon their visit order and random digital table, an acupuncture plus Chinese herbs (APCH) group, an acupuncture group, and a Western medication (WM) group, 30 cases in each group. The APCH group was treated by puncturing Fengchi (GB 20), Fengfu (GV 16) and Fengmen (BL 12), without retaining the needles, and then by puncturing Zhongwan (CV 12), Guanyuan (CV 4), Qihai (CV 6) and Tianshu (ST 25) with reinforcing technique after arrival of the needling sensation, and the needles were retained for 30 min, plus oral administration of wind-expelling Chinese herbs. The acupuncture group was treated with the acupoints selected by syndrome differentiation in reference to the textbook of Acupuncture and Moxibustion Science. The WM group was treated by intravenous infusion of Alprostadil injection, Adenosine Disodium Triphosphate and Coenzyme A and muscular injection of Vitamin B12 and Vitamin B1. The decibel values of hearing loss before and after treatment were respectively recorded and analyzed comparatively.
Results:In the intra-group comparison after treatment among the three groups, the decibel values of hearing loss all declined, with statistically significant differences (allP<0.05). After treatment, the decibel value of hearing loss in the APCH group was better than those in the acupuncture group (P<0.05) and the WM group (P<0.05). The total effective rate was respectively 83.3% in the APCH group, 60.0% in the acupuncture group and 56.7% in the WM group. The total effective rate in the APCH group was better than those in other two groups (bothP<0.05).
Conclusion:The therapeutic effect was better for sudden deafness by wind-expelling method of acupuncture and Chinese herbs than by acupuncture alone or by Western medication.
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