Objective:To analyze the epidemiological characteristics of comorbidity of post-traumatic stress disorder and depression symptoms among active firefighters, and explore its influencing factors.Methods:In November 2021, a cross-sectional study was conducted using a combination of convenience sampling and cluster sampling. Active firefighters were selected as the research subjects for a questionnaire survey. 1100 questionnaires were distributed, 1032 were collected, and 1021 were valid, with an effective response rate of 98.93%. The PTSD prevalence and characteristics of firefighters were assessed by using the PTSD Checklist Civilian Version (PCL-C) . The degree of depression was assessed by the Patient Health Questionnaire (PHQ-9) . The coping style was assessed by the Trait Coping Style Questionnaire, and the Social Support Rate Scale was used to investigate the degree of social support. Combined with the general information, the influencing factors of comorbidity of PTSD and symptoms of depression in firefighters were analyzed with binary logistic regression based on single factor analysis.Results:Among 1021 firefighters, 379 had a PHQ-9 score of ≥5, and the prevalence rate of depression was 37.1% (379/1 021) . The prevalence rate of PTSD is 4.6% for 47 individuals with a total PCL-C score of ≥38, and the comorbidity rate of depressive symptoms among PTSD patients is 100%. Logistic regression analysis showed that injuries in the past six months, average/poor self-rated health status, and negative coping were all promoting factors for both the simple depression symptom group and the comorbidity group, while social support was the hindering factor ( P<0.05) . Two sets of OR values show that negative coping and social support have roughly the same degree of impact in both groups. The OR (95% CI) values of the two factors of being injured in the past six months and self-rated as average/poor health status have significantly increased in the comorbidity group. The OR (95% CI) values of being injured in the past six months has increased from 2.20 (1.24, 3.93) in the simple depression symptom group to 3.44 (1.30, 9.09) in the comorbidity group, and that of the self-rated as average and poor health status has increased from 4.91 (3.01, 8.00) to 6.56 (1.97, 21.87) and from 7.96 (2.25, 28.25) to 19.17 (4.75, 77.31) separately ( P<0.05) . Conclusion:The results indicate that firefighters with PTSD generally have comorbidity with depressive symptoms. The common influencing factor of being injured in the past six months is consistent with the pattern of PTSD symptoms triggered by depressive symptoms.

Objective:To analyze the epidemiological characteristics of comorbidity of post-traumatic stress disorder and depression symptoms among active firefighters, and explore its influencing factors.Methods:In November 2021, a cross-sectional study was conducted using a combination of convenience sampling and cluster sampling. Active firefighters were selected as the research subjects for a questionnaire survey. 1100 questionnaires were distributed, 1032 were collected, and 1021 were valid, with an effective response rate of 98.93%. The PTSD prevalence and characteristics of firefighters were assessed by using the PTSD Checklist Civilian Version (PCL-C) . The degree of depression was assessed by the Patient Health Questionnaire (PHQ-9) . The coping style was assessed by the Trait Coping Style Questionnaire, and the Social Support Rate Scale was used to investigate the degree of social support. Combined with the general information, the influencing factors of comorbidity of PTSD and symptoms of depression in firefighters were analyzed with binary logistic regression based on single factor analysis.Results:Among 1021 firefighters, 379 had a PHQ-9 score of ≥5, and the prevalence rate of depression was 37.1% (379/1 021) . The prevalence rate of PTSD is 4.6% for 47 individuals with a total PCL-C score of ≥38, and the comorbidity rate of depressive symptoms among PTSD patients is 100%. Logistic regression analysis showed that injuries in the past six months, average/poor self-rated health status, and negative coping were all promoting factors for both the simple depression symptom group and the comorbidity group, while social support was the hindering factor ( P<0.05) . Two sets of OR values show that negative coping and social support have roughly the same degree of impact in both groups. The OR (95% CI) values of the two factors of being injured in the past six months and self-rated as average/poor health status have significantly increased in the comorbidity group. The OR (95% CI) values of being injured in the past six months has increased from 2.20 (1.24, 3.93) in the simple depression symptom group to 3.44 (1.30, 9.09) in the comorbidity group, and that of the self-rated as average and poor health status has increased from 4.91 (3.01, 8.00) to 6.56 (1.97, 21.87) and from 7.96 (2.25, 28.25) to 19.17 (4.75, 77.31) separately ( P<0.05) . Conclusion:The results indicate that firefighters with PTSD generally have comorbidity with depressive symptoms. The common influencing factor of being injured in the past six months is consistent with the pattern of PTSD symptoms triggered by depressive symptoms.

{L-End}Objective To analyze the current status of post-traumatic stress disorder (PTSD) among firefighters in Chongqing City and explore its influencing factors. {L-End}Methods A total of 1 021 firefighters in Chongqing City were selected as the study subjects using the convenient sampling method. The PTSD Checklist Civilian Version was used to assess their PTSD symptom and characteristics. The Trait Coping Style Questionnaire and the Social Support Rating Scale were used to investigate coping styles and the level of social support. {L-End}Results The positive detection rate of PTSD among the study subjects was 4.6%(47/1 021), with positive detection rates of re-experiencing, avoidance/numbing, and hyperarousal symptoms of 7.0%, 9.2%, and 16.5%, respectively. The positive detection rates of re-experiencing, avoidance/numbing, and hyperarousal symptoms in the PTSD firefighters were higher than those in non-PTSD firefighters (83.0% vs 3.3%, 93.6% vs 5.1%, 100.0% vs 12.1%, respectively; all P<0.01). The results of the multivariate logistic regression analysis showed that being injured in the past six months and adopting a negative coping style were risk factors for PTSD ［odds ratio (OR) and 95% confidence interval (CI) were 2.65 (1.07-6.56) and 1.26 (1.19-1.33), respectively; both P<0.05］, while adopting a positive coping style and having a higher level of social support were protective factors for PTSD ［OR and 95%CI were 0.90 (0.85-0.95) and 0.95 (0.91-0.99), respectively; both P<0.05］. {L-End}Conclusion The incidence of PTSD among the firefighters in Chongqing City is relatively high, with symptoms mainly characterized by hyperarousal. Being injured in the past six months, coping styles, and the level of social support are influencing factors for PTSD.

Objective: To analyze the effect of job characteristics and organizational support for workplace violence, explore the influence path and the theoretical model, and provide a theoretical basis for reducing workplace violence. Methods: Stratified random sampling was used to select 813 medical staff, conductors and bus drivers in Chongqing with a self-made questionnaire to investigate job characteristics, organization attitude toward workplace violence, workplace violence, fear of violence, workplace violence, etc from February to October, 2014. Amos 21.0 was used to analyze the path and to establish a theoretical model of workplace violence. Results: The odds ratio of work characteristics and organizational attitude to workplace violence were 6.033 and 0.669, respectively, and the path coefficients were 0.41 and-0.14, respectively (P<0.05). The Fitting indexes of the model: Chi-square (χ²) =67.835, The ratio of the chi-square to the degree of freedom (χ²/df) =5.112, Good-of-fit index (GFI) =0.970, Adjusted good-of-fit index (AGFI) =0.945, Normed fit index (NFI) =0.923, Root mean square error of approximation (RMSEA) =0.071, Fit criterion (Fmin) =0.092, so the model fit well with the data. Conclusion The job characteristic is a risk factor for workplace violence while organizational attitude is a protective factor for workplace violence, so changing the job characteristics and improving the enthusiasm of the organization to deal with workplace violence are conducive to reduce workplace violence and increase loyalty to the unit.

Objective:To establish a determination method for the content of cyproheptadine hydyochloride tablets and the related substances in the tablets by HPLC. Methods:The assay was performed on a CAPCELL PAK C18(Shiseido)(250 mm ×4.6 mm, 5μm) column with methanol-0. 002 5mol·L-1 sodium heptanesulfonate (adjusting pH to 3 with phosphoric acid)(60: 40) as the mo-bile phase. The detection wavelength was 225 nm, the flow rate was 1. 0 ml·min-1 , the column temperature was 30℃ and the sample size was 10 μl. Results: Cyproheptadine hydyochloride had good linear relationship within the range of 4. 12-82. 40 μg·ml-1 ( r=1. 000 0), and the average recovery was 99. 2%(RSD=0. 8%, n=9). The peaks of the related substances were well separated from that of cyproheptadine hydrochloride. Conclusion:The method is simple, fast and accurate, and can be used for the quality control of cyproheptadine hydyochloride tablets.